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Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial

Journal of clinical oncology, 2019-03, Vol.37 (9), p.741-750

2019

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Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation

The Journal of biological chemistry, 2016-02, Vol.291 (9), p.4547-4560

2016

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SHORT Syndrome with Partial Lipodystrophy Due to Impaired Phosphatidylinositol 3 Kinase Signaling

American journal of human genetics, 2013-07, Vol.93 (1), p.150-157

2013

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PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α

Proceedings of the National Academy of Sciences - PNAS, 2017-07, Vol.114 (27), p.7095-7100

2017

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TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

Nature (London), 2020-02, Vol.578 (7796), p.605-609

2020

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A module for Rac temporal signal integration revealed with optogenetics

The Journal of cell biology, 2017-08, Vol.216 (8), p.2515-2531

2017

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Phosphoinositide‐3 kinase gamma regulates caspase‐1 activation and leukocyte recruitment in acute murine gout

Journal of leukocyte biology, 2019-09, Vol.106 (3), p.619-629

2019

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MYC Acts via the PTEN Tumor Suppressor to Elicit Autoregulation and Genome-Wide Gene Repression by Activation of the Ezh2 Methyltransferase

Cancer research (Chicago, Ill.), 2013-01, Vol.73 (2), p.695-705

2013

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p85β increases phosphoinositide 3-kinase activity and accelerates tumor progression

Cell cycle (Georgetown, Tex.), 2012-10, Vol.11 (19), p.3523-3524

2012

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PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control

PLoS biology, 2013-06, Vol.11 (6), p.e1001587

2013

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Caffeine induces endothelial tissue factor expression via phosphatidylinositol 3-kinase inhibition

Thrombosis and haemostasis, 2012-05, Vol.107 (5), p.884

2012

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Regulation of CD38 expression in human airway smooth muscle cells: role of class I phosphatidylinositol 3 kinases

American journal of respiratory cell and molecular biology, 2012-10, Vol.47 (4), p.427-435

2012

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GBF1 bears a novel phosphatidylinositol-phosphate binding module, BP3K, to link PI3Kγ activity with Arf1 activation involved in GPCR-mediated neutrophil chemotaxis and superoxide production

Molecular biology of the cell, 2012-07, Vol.23 (13), p.2457-2467

2012

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Activation of the phosphatidylinositol 3′-kinase/AKT pathway in neuroblastoma and its regulation by thioredoxin 1

Human pathology, 2011-11, Vol.42 (11), p.1727-1739

2011

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Phosphoinositide 3-Kinase-dependent and -independent Activation of the Small GTPase Rac2 in Human Neutrophils

The Journal of biological chemistry, 1999-06, Vol.274 (25), p.18055-18059

1999

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Delta-like 1/Fetal Antigen-1 (Dlk1/FA1) Is a Novel Regulator of Chondrogenic Cell Differentiation via Inhibition of the Akt Kinase-dependent Pathway

The Journal of biological chemistry, 2011-09, Vol.286 (37), p.32140-32149

2011

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Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

The Journal of biological chemistry, 2001-03, Vol.276 (13), p.9817-9824

2001

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Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA)

Proceedings of the National Academy of Sciences - PNAS, 2012-09, Vol.109 (38), p.15259-15264

2012

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Akt/Protein Kinase B Isoforms Are Differentially Regulated by Epidermal Growth Factor Stimulation

The Journal of biological chemistry, 2000-10, Vol.275 (40), p.30934-30942

2000

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Syk and Bruton's Tyrosine Kinase Are Required for B Cell Antigen Receptor-mediated Activation of the Kinase Akt

The Journal of biological chemistry, 1999-10, Vol.274 (43), p.30644-30650

1999

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Phosphoinositide 3-kinase signalling pathways

Journal of cell science, 2001-04, Vol.114 (Pt 8), p.1439-1445

Cantrell, D A

2001

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Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence

Blood, 2014-01, Vol.123 (2), p.239-248

2014

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Reduced Phosphoinositide 3-Kinase (p110α) Activation Increases the Susceptibility to Atrial Fibrillation

The American journal of pathology, 2009-09, Vol.175 (3), p.998-1009

2009

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Maternal and fetal genomes interplay through phosphoinositol 3-kinase(PI3K)-p110α signaling to modify placental resource allocation

Proceedings of the National Academy of Sciences - PNAS, 2016-10, Vol.113 (40), p.11255-11260

2016

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Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pathway

The Journal of biological chemistry, 2004-07, Vol.279 (31), p.32869-32881

2004

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Buparlisib in Patients With Recurrent Glioblastoma Harboring Phosphatidylinositol 3-Kinase Pathway Activation: An Open-Label, Multicenter, Multi-Arm, Phase II Trial

Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation

SHORT Syndrome with Partial Lipodystrophy Due to Impaired Phosphatidylinositol 3 Kinase Signaling

PI3K-p110α mediates the oncogenic activity induced by loss of the novel tumor suppressor PI3K-p85α

TLR9 and beclin 1 crosstalk regulates muscle AMPK activation in exercise

A module for Rac temporal signal integration revealed with optogenetics

Phosphoinositide‐3 kinase gamma regulates caspase‐1 activation and leukocyte recruitment in acute murine gout

MYC Acts via the PTEN Tumor Suppressor to Elicit Autoregulation and Genome-Wide Gene Repression by Activation of the Ezh2 Methyltransferase

p85β increases phosphoinositide 3-kinase activity and accelerates tumor progression

PKCβ phosphorylates PI3Kγ to activate it and release it from GPCR control

Caffeine induces endothelial tissue factor expression via phosphatidylinositol 3-kinase inhibition

Regulation of CD38 expression in human airway smooth muscle cells: role of class I phosphatidylinositol 3 kinases

GBF1 bears a novel phosphatidylinositol-phosphate binding module, BP3K, to link PI3Kγ activity with Arf1 activation involved in GPCR-mediated neutrophil chemotaxis and superoxide production

Activation of the phosphatidylinositol 3′-kinase/AKT pathway in neuroblastoma and its regulation by thioredoxin 1

Phosphoinositide 3-Kinase-dependent and -independent Activation of the Small GTPase Rac2 in Human Neutrophils

Delta-like 1/Fetal Antigen-1 (Dlk1/FA1) Is a Novel Regulator of Chondrogenic Cell Differentiation via Inhibition of the Akt Kinase-dependent Pathway

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor alpha: a new model for anti-estrogen resistance

Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA)

Akt/Protein Kinase B Isoforms Are Differentially Regulated by Epidermal Growth Factor Stimulation

Syk and Bruton's Tyrosine Kinase Are Required for B Cell Antigen Receptor-mediated Activation of the Kinase Akt

Phosphoinositide 3-kinase signalling pathways

Phosphoinositide 3-kinase inhibition restores neutrophil accuracy in the elderly: toward targeted treatments for immunosenescence

Reduced Phosphoinositide 3-Kinase (p110α) Activation Increases the Susceptibility to Atrial Fibrillation

Maternal and fetal genomes interplay through phosphoinositol 3-kinase(PI3K)-p110α signaling to modify placental resource allocation

Tumor necrosis factor (TNF)-mediated neuroprotection against glutamate-induced excitotoxicity is enhanced by N-methyl-D-aspartate receptor activation. Essential role of a TNF receptor 2-mediated phosphatidylinositol 3-kinase-dependent NF-kappa B pathway

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