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Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy

Proceedings of the National Academy of Sciences - PNAS, 2021-12, Vol.118 (52), p.1-10

2021

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The AMPK-PP2A axis in insect fat body is activated by 20-hydroxyecdysone to antagonize insulin/IGF signaling and restrict growth rate

Proceedings of the National Academy of Sciences - PNAS, 2020-04, Vol.117 (17), p.9292-9301

2020

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Steroid signaling mediates nutritional regulation of juvenile body growth via IGF-binding protein in Drosophila

Proceedings of the National Academy of Sciences - PNAS, 2018-06, Vol.115 (23), p.5992-5997

2018

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The Insulin-Like Growth Factor (IGF)-Dependent IGF Binding Protein-4 Protease Secreted by Human Fibroblasts Is Pregnancy-Associated Plasma Protein-A

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (6), p.3149-3153

1999

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Liver-Derived Insulin-Like Growth Factor I (IGF-I) Is the Principal Source of IGF-I in Blood but Is Not Required for Postnatal Body Growth in Mice

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (12), p.7088-7092

1999

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Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk

Proceedings of the National Academy of Sciences - PNAS, 2007-12, Vol.104 (52), p.20926-20931

2007

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An Insulin-Like Growth Factor (IGF) Binding Protein Enhances the Biologic Response to IGF-I

Proceedings of the National Academy of Sciences - PNAS, 1987-05, Vol.84 (10), p.3254-3258

1987

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Inhibition of Growth, Production of Insulin-Like Growth Factor-II (IGF-II), and Expression of IGF-II mRNA of Human Cancer Cell Lines by Antagonistic Analogs of Growth Hormone-Releasing Hormone in vitro

Proceedings of the National Academy of Sciences - PNAS, 1999-03, Vol.96 (6), p.3098-3103

1999

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Functionally significant insulin-like growth factor I receptor mutations in centenarians

Proceedings of the National Academy of Sciences - PNAS, 2008-03, Vol.105 (9), p.3438-3442

2008

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Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction

Proceedings of the National Academy of Sciences - PNAS, 2017-09, Vol.114 (36), p.9731-9736

2017

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Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors

Proceedings of the National Academy of Sciences - PNAS, 2008-06, Vol.105 (24), p.8387-8392

2008

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Isolation of an Inhibitory Insulin-Like Growth Factor (IGF) Binding Protein from Bone Cell-Conditioned Medium: A Potential Local Regulator of IGF Action

Proceedings of the National Academy of Sciences - PNAS, 1989-11, Vol.86 (21), p.8338-8342

1989

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Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (24), p.10791-10798

2010

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Monoclonal Antibody to the Type I Insulin-Like Growth Factor (IGF-I) Receptor Blocks IGF-I Receptor-Mediated DNA Synthesis: Clarification of the Mitogenic Mechanisms of IGF-I and Insulin in Human Skin Fibroblasts

Proceedings of the National Academy of Sciences - PNAS, 1986-02, Vol.83 (3), p.664-668

1986

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Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (13), p.6379-6384

2019

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Phosphorylation of Insulin-Like Growth Factor (IGF)-Binding Protein 1 in Cell Culture and in vivo: Effects on Affinity for IGF-I

Proceedings of the National Academy of Sciences - PNAS, 1991-09, Vol.88 (17), p.7481-7485

1991

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The First Three Domains of the Insulin Receptor Differ Structurally from the Insulin-like Growth Factor 1 Receptor in the Regions Governing Ligand Specificity

Proceedings of the National Academy of Sciences - PNAS, 2006-08, Vol.103 (33), p.12429-12434

2006

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Insulin-like Growth Factors 1 and 2 Induce Lymphangiogenesis in vivo

Proceedings of the National Academy of Sciences - PNAS, 2005-10, Vol.102 (43), p.15593-15598

2005

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Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes

Proceedings of the National Academy of Sciences - PNAS, 2014-10, Vol.111 (40), p.14512-14517

2014

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The developmental basis for scaling of mammalian tooth size

Proceedings of the National Academy of Sciences - PNAS, 2023-06, Vol.120 (25), p.e2300374120-e2300374120

2023

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Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

Proceedings of the National Academy of Sciences - PNAS, 2021-04, Vol.118 (17), p.1-12

2021

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The Role of Shc and Insulin-Like Growth Factor 1 Receptor in Mediating the Translocation of Estrogen Receptor α to the Plasma Membrane

Proceedings of the National Academy of Sciences - PNAS, 2004-02, Vol.101 (7), p.2076-2081

2004

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Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host–microbe interactions

Proceedings of the National Academy of Sciences - PNAS, 2018-03, Vol.115 (10), p.2461-2466

2018

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Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.E3582-E3589

2015

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Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling

Proceedings of the National Academy of Sciences - PNAS, 2019-03, Vol.116 (13), p.5852-5854

2019

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Therapeutic IGF-I receptor inhibition alters fibrocyte immune phenotype in thyroid-associated ophthalmopathy

The AMPK-PP2A axis in insect fat body is activated by 20-hydroxyecdysone to antagonize insulin/IGF signaling and restrict growth rate

Steroid signaling mediates nutritional regulation of juvenile body growth via IGF-binding protein in Drosophila

The Insulin-Like Growth Factor (IGF)-Dependent IGF Binding Protein-4 Protease Secreted by Human Fibroblasts Is Pregnancy-Associated Plasma Protein-A

Liver-Derived Insulin-Like Growth Factor I (IGF-I) Is the Principal Source of IGF-I in Blood but Is Not Required for Postnatal Body Growth in Mice

Enhanced sensitivity to IGF-II signaling links loss of imprinting of IGF2 to increased cell proliferation and tumor risk

An Insulin-Like Growth Factor (IGF) Binding Protein Enhances the Biologic Response to IGF-I

Inhibition of Growth, Production of Insulin-Like Growth Factor-II (IGF-II), and Expression of IGF-II mRNA of Human Cancer Cell Lines by Antagonistic Analogs of Growth Hormone-Releasing Hormone in vitro

Functionally significant insulin-like growth factor I receptor mutations in centenarians

Insulin-like growth factor 1 receptor regulates hypothermia during calorie restriction

Insulin-like growth factor 1 receptor is a potential therapeutic target for gastrointestinal stromal tumors

Isolation of an Inhibitory Insulin-Like Growth Factor (IGF) Binding Protein from Bone Cell-Conditioned Medium: A Potential Local Regulator of IGF Action

Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy

Monoclonal Antibody to the Type I Insulin-Like Growth Factor (IGF-I) Receptor Blocks IGF-I Receptor-Mediated DNA Synthesis: Clarification of the Mitogenic Mechanisms of IGF-I and Insulin in Human Skin Fibroblasts

Insulin signaling in the hippocampus and amygdala regulates metabolism and neurobehavior

Phosphorylation of Insulin-Like Growth Factor (IGF)-Binding Protein 1 in Cell Culture and in vivo: Effects on Affinity for IGF-I

The First Three Domains of the Insulin Receptor Differ Structurally from the Insulin-like Growth Factor 1 Receptor in the Regions Governing Ligand Specificity

Insulin-like Growth Factors 1 and 2 Induce Lymphangiogenesis in vivo

Insulin and insulin-like growth factor 1 receptors are required for normal expression of imprinted genes

The developmental basis for scaling of mammalian tooth size

Distinct signaling by insulin and IGF-1 receptors and their extra- and intracellular domains

The Role of Shc and Insulin-Like Growth Factor 1 Receptor in Mediating the Translocation of Estrogen Receptor α to the Plasma Membrane

Viral insulin-like peptides activate human insulin and IGF-1 receptor signaling: A paradigm shift for host–microbe interactions

Enhanced memory consolidation in mice lacking the circadian modulators Sharp1 and -2 caused by elevated Igf2 signaling in the cortex

Unexpected systemic phenotypes result from focal combined deficiencies of forebrain insulin receptor/IGF-1 receptor signaling

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