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CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element

Nature communications, 2022-03, Vol.13 (1), p.1477-1477, Article 1477

2022

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High-affinity caspase-4 binding to LPS presented as high molecular mass aggregates or in outer membrane vesicles

Innate immunity (London, England), 2017-05, Vol.23 (4), p.336-344

2017

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Isolation of an Endotoxin-MD-2 Complex That Produces Toll-Like Receptor 4-Dependent Cell Activation at Picomolar Concentrations

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (12), p.4186-4191

2004

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Endotoxin·albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

Innate immunity (London, England), 2012-06, Vol.18 (3), p.478-491

2012

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Biochemical and Functional Characterization of Membrane Blebs Purified from Neisseria meningitidis Serogroup B

The Journal of biological chemistry, 2005-11, Vol.280 (46), p.38383-38394

2005

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Novel Roles in Human MD-2 of Phenylalanines 121 and 126 and Tyrosine 131 in Activation of Toll-like Receptor 4 by Endotoxin

The Journal of biological chemistry, 2008-01, Vol.283 (3), p.1257-1266

2008

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Transfer of Monomeric Endotoxin from MD-2 to CD14

The Journal of biological chemistry, 2007-12, Vol.282 (50), p.36250-36256

2007

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An Essential Role for Albumin in the Interaction of Endotoxin with Lipopolysaccharide-binding Protein and sCD14 and Resultant Cell Activation

The Journal of biological chemistry, 2002-12, Vol.277 (49), p.47818-47825

2002

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Endotoxin-binding Proteins Modulate the Susceptibility of Bacterial Endotoxin to Deacylation by Acyloxyacyl Hydrolase

The Journal of biological chemistry, 2007-03, Vol.282 (11), p.7877-7884

2007

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DNA demethylation fine-tunes IL-2 production during thymic development and promotes Regulatory T cell differentiation

The Journal of immunology (1950), 2023-05, Vol.210 (1_Supplement), p.76-76.24

2023

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Modulation of phagocytosis‐induced cell death of human neutrophils by Neisseria gonorrhoeae

Journal of leukocyte biology, 2020-11, Vol.108 (5), p.1543-1553

2020

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DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation

EMBO reports, 2023-05, Vol.24 (5), p.e55543-n/a

2023

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Construction of Acetate Auxotrophs of Neisseria meningitidis to Study Host-Meningococcal Endotoxin Interactions

The Journal of biological chemistry, 2001-02, Vol.276 (8), p.5883-5891

2001

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Evidence of a Specific Interaction between New Synthetic Antisepsis Agents and CD14

Biochemistry (Easton), 2009-12, Vol.48 (51), p.12337-12344

2009

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NMR Studies of Hexaacylated Endotoxin Bound to Wild-type and F126A Mutant MD-2 and MD-2·TLR4 Ectodomain Complexes

The Journal of biological chemistry, 2012-05, Vol.287 (20), p.16346-16355

2012

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Purified monomeric ligand.MD-2 complexes reveal molecular and structural requirements for activation and antagonism of TLR4 by Gram-negative bacterial endotoxins

Immunologic research, 2014-08, Vol.59 (1-3), p.3-11

2014

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Molecular Basis of Reduced Potency of Underacylated Endotoxins

Journal of Immunology, 2005-10, Vol.175 (7), p.4669-4676

2005

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Specific High Affinity Interactions of Monomeric Endotoxin·Protein Complexes with Toll-like Receptor 4 Ectodomain

The Journal of biological chemistry, 2007-01, Vol.282 (2), p.1010-1017

2007

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Radioiodination of an endotoxin·MD-2 complex generates a novel sensitive, high-affinity ligand for TLR4

Innate immunity (London, England), 2013-10, Vol.19 (5), p.545-560

2013

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Isolation of Monomeric and Dimeric Secreted MD-2: ENDOTOXIN·sCD14 AND TOLL-LIKE RECEPTOR 4 ECTODOMAIN SELECTIVELY REACT WITH THE MONOMERIC FORM OF SECRETED MD-2

The Journal of biological chemistry, 2008-08, Vol.283 (32), p.21881-21889

2008

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Radioiodination of an endotoxin.MD-2 complex generates a novel sensitive, high-affinity ligand for TLR4

Innate immunity (London, England), 2013-10, Vol.19 (5), p.545-560

2013

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Isolation of monomeric and dimeric secreted MD-2. Endotoxin.sCD14 and Toll-like receptor 4 ectodomain selectively react with the monomeric form of secreted MD-2

The Journal of biological chemistry, 2008-08, Vol.283 (32), p.21881-21889

2008

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Endotoxin.albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

Innate immunity (London, England), 2012-06, Vol.18 (3), p.478-491

2012

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Transfer of Monomeric Endotoxin from MD-2 to CD14: CHARACTERIZATION AND FUNCTIONAL CONSEQUENCES

The Journal of biological chemistry, 2007-12, Vol.282 (50), p.36250-36256

2007

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Essential role of albumin in CD14-independent activation of MD-2/TLR4 by endotoxin (135.20)

The Journal of immunology (1950), 2009-04, Vol.182 (1_Supplement), p.135-135.20

2009

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CD4 expression in effector T cells depends on DNA demethylation over a developmentally established stimulus-responsive element

High-affinity caspase-4 binding to LPS presented as high molecular mass aggregates or in outer membrane vesicles

Isolation of an Endotoxin-MD-2 Complex That Produces Toll-Like Receptor 4-Dependent Cell Activation at Picomolar Concentrations

Endotoxin·albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

Biochemical and Functional Characterization of Membrane Blebs Purified from Neisseria meningitidis Serogroup B

Novel Roles in Human MD-2 of Phenylalanines 121 and 126 and Tyrosine 131 in Activation of Toll-like Receptor 4 by Endotoxin

Transfer of Monomeric Endotoxin from MD-2 to CD14

An Essential Role for Albumin in the Interaction of Endotoxin with Lipopolysaccharide-binding Protein and sCD14 and Resultant Cell Activation

Endotoxin-binding Proteins Modulate the Susceptibility of Bacterial Endotoxin to Deacylation by Acyloxyacyl Hydrolase

DNA demethylation fine-tunes IL-2 production during thymic development and promotes Regulatory T cell differentiation

Modulation of phagocytosis‐induced cell death of human neutrophils by Neisseria gonorrhoeae

DNA demethylation fine‐tunes IL‐2 production during thymic regulatory T cell differentiation

Construction of Acetate Auxotrophs of Neisseria meningitidis to Study Host-Meningococcal Endotoxin Interactions

Evidence of a Specific Interaction between New Synthetic Antisepsis Agents and CD14

NMR Studies of Hexaacylated Endotoxin Bound to Wild-type and F126A Mutant MD-2 and MD-2·TLR4 Ectodomain Complexes

Purified monomeric ligand.MD-2 complexes reveal molecular and structural requirements for activation and antagonism of TLR4 by Gram-negative bacterial endotoxins

Molecular Basis of Reduced Potency of Underacylated Endotoxins

Specific High Affinity Interactions of Monomeric Endotoxin·Protein Complexes with Toll-like Receptor 4 Ectodomain

Radioiodination of an endotoxin·MD-2 complex generates a novel sensitive, high-affinity ligand for TLR4

Isolation of Monomeric and Dimeric Secreted MD-2: ENDOTOXIN·sCD14 AND TOLL-LIKE RECEPTOR 4 ECTODOMAIN SELECTIVELY REACT WITH THE MONOMERIC FORM OF SECRETED MD-2

Radioiodination of an endotoxin.MD-2 complex generates a novel sensitive, high-affinity ligand for TLR4

Isolation of monomeric and dimeric secreted MD-2. Endotoxin.sCD14 and Toll-like receptor 4 ectodomain selectively react with the monomeric form of secreted MD-2

Endotoxin.albumin complexes transfer endotoxin monomers to MD-2 resulting in activation of TLR4

Transfer of Monomeric Endotoxin from MD-2 to CD14: CHARACTERIZATION AND FUNCTIONAL CONSEQUENCES

Essential role of albumin in CD14-independent activation of MD-2/TLR4 by endotoxin (135.20)

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