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Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β -Glucuronidases in Their Disposition

Drug metabolism and disposition, 2017-06, Vol.45 (6), p.657-665

2017

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Pharmacokinetics, Disposition, and Biotransformation of [ 14 C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose

Drug metabolism and disposition, 2021-08, Vol.49 (8), p.619-628

2021

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Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry

Drug metabolism and disposition, 2014-12, Vol.42 (12), p.2023-2032

2014

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Pharmacokinetics, Disposition, and Biotransformation of [14C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion

Clinical pharmacokinetics, 2024-02, Vol.63 (2), p.241-253

2024

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Pharmacokinetics and pharmacodynamics of nab-paclitaxel in patients with solid tumors: Disposition kinetics and pharmacology distinct from solvent-based paclitaxel

Journal of clinical pharmacology, 2014-10, Vol.54 (10), p.1097-1107

2014

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Disposition and metabolism of [14C] Sacubitril/Valsartan (formerly LCZ696) an angiotensin receptor neprilysin inhibitor, in healthy subjects

Xenobiotica, 2016-11, Vol.46 (11), p.986-1000

2016

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Treatment With Antipsychotics in Pregnancy: Changes in Drug Disposition

Clinical pharmacology and therapeutics, 2018-03, Vol.103 (3), p.477-484

2018

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Brivaracetam Disposition in Renal Impairment

Journal of clinical pharmacology, 2012-12, Vol.52 (12), p.1927-1933

2012

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A pregnancy physiologically based pharmacokinetic (p‐PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4

British journal of clinical pharmacology, 2012-11, Vol.74 (5), p.873-885

2012

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Disposition, metabolism and mass balance of [14C]apremilast following oral administration

Xenobiotica, 2011-12, Vol.41 (12), p.1063-1075

2011

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Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

Pharmaceutical research, 2012-10, Vol.29 (10), p.2860-2873

2012

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Complex disposition of methylthioninium redox forms determines efficacy in tau aggregation inhibitor therapy for Alzheimer's disease

The Journal of pharmacology and experimental therapeutics, 2015-01, Vol.352 (1), p.110-118

2015

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Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Drug metabolism and disposition, 2013-06, Vol.41 (6), p.1179-1186

2013

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Effects of Pregnancy on CYP3A and P-glycoprotein Activities as Measured by Disposition of Midazolam and Digoxin: A University of Washington Specialized Center of Research Study

Clinical pharmacology and therapeutics, 2008-08, Vol.84 (2), p.248-253

2008

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Bronchopulmonary disposition of IV cefepime/taniborbactam (2–0.5 g) administered over 2 h in healthy adult subjects

Journal of antimicrobial chemotherapy, 2023-03, Vol.78 (3), p.703-709

2023

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Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans

Drug metabolism and disposition, 2016-01, Vol.44 (1), p.28-39

2016

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Pharmacogenetics of artemether‐lumefantrine influence on nevirapine disposition: Clinically significant drug–drug interaction?

British journal of clinical pharmacology, 2019-03, Vol.85 (3), p.540-550

2019

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Characterizing the Nonlinear Pharmacokinetics and Pharmacodynamics of BI 187004, an 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitor, in Humans by a Target‐Mediated Drug Disposition Model

Journal of clinical pharmacology, 2024-08, Vol.64 (8), p.993-1005

2024

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The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans

Drug metabolism and disposition, 2008-02, Vol.36 (2), p.386-399

2008

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Imatinib Disposition and ABCB1 (MDR1, P‐Glycoprotein) Genotype

Clinical pharmacology and therapeutics, 2007-07, Vol.82 (1), p.33-40

2007

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Clinical disposition, metabolism and in vitro drug-drug interaction properties of omadacycline

Xenobiotica, 2017-08, Vol.47 (8), p.682-696

2017

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Common Polymorphisms of CYP2B6 Influence Stereoselective Bupropion Disposition

Clinical pharmacology and therapeutics, 2019-01, Vol.105 (1), p.142-152

2019

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Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans

Acta pharmacologica Sinica, 2022-02, Vol.43 (2), p.494-503

2022

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Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography

Clinical pharmacology and therapeutics, 2018-07, Vol.104 (1), p.139-147

2018

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Predicting Maternal-Fetal Disposition of Fentanyl Following Intravenous and Epidural Administration Using Physiologically Based Pharmacokinetic Modeling

Drug metabolism and disposition, 2021-11, Vol.49 (11), p.1003-1015

2021

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Phase II Conjugates of Urolithins Isolated from Human Urine and Potential Role of β -Glucuronidases in Their Disposition

Pharmacokinetics, Disposition, and Biotransformation of [ 14 C]Omecamtiv Mecarbil in Healthy Male Subjects after a Single Intravenous or Oral Dose

Disposition and metabolic profiling of [(14)C]cerlapirdine using accelerator mass spectrometry

Pharmacokinetics, Disposition, and Biotransformation of [14C]Lenacapavir, a Novel, First-in-Class, Selective Inhibitor of HIV-1 Capsid Function, in Healthy Participants Following a Single Intravenous Infusion

Pharmacokinetics and pharmacodynamics of nab-paclitaxel in patients with solid tumors: Disposition kinetics and pharmacology distinct from solvent-based paclitaxel

Disposition and metabolism of [14C] Sacubitril/Valsartan (formerly LCZ696) an angiotensin receptor neprilysin inhibitor, in healthy subjects

Treatment With Antipsychotics in Pregnancy: Changes in Drug Disposition

Brivaracetam Disposition in Renal Impairment

A pregnancy physiologically based pharmacokinetic (p‐PBPK) model for disposition of drugs metabolized by CYP1A2, CYP2D6 and CYP3A4

Disposition, metabolism and mass balance of [14C]apremilast following oral administration

Physiologically Based Modeling of Pravastatin Transporter-Mediated Hepatobiliary Disposition and Drug-Drug Interactions

Complex disposition of methylthioninium redox forms determines efficacy in tau aggregation inhibitor therapy for Alzheimer's disease

Sorafenib hepatobiliary disposition: mechanisms of hepatic uptake and disposition of generated metabolites

Effects of Pregnancy on CYP3A and P-glycoprotein Activities as Measured by Disposition of Midazolam and Digoxin: A University of Washington Specialized Center of Research Study

Bronchopulmonary disposition of IV cefepime/taniborbactam (2–0.5 g) administered over 2 h in healthy adult subjects

Absorption, Metabolism, Excretion, and the Contribution of Intestinal Metabolism to the Oral Disposition of [14C]Cobimetinib, a MEK Inhibitor, in Humans

Pharmacogenetics of artemether‐lumefantrine influence on nevirapine disposition: Clinically significant drug–drug interaction?

Characterizing the Nonlinear Pharmacokinetics and Pharmacodynamics of BI 187004, an 11β‐Hydroxysteroid Dehydrogenase Type 1 Inhibitor, in Humans by a Target‐Mediated Drug Disposition Model

The metabolism and disposition of the oral direct thrombin inhibitor, dabigatran, in humans

Imatinib Disposition and ABCB1 (MDR1, P‐Glycoprotein) Genotype

Clinical disposition, metabolism and in vitro drug-drug interaction properties of omadacycline

Common Polymorphisms of CYP2B6 Influence Stereoselective Bupropion Disposition

Metabolic disposition of the EGFR covalent inhibitor furmonertinib in humans

Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography

Predicting Maternal-Fetal Disposition of Fentanyl Following Intravenous and Epidural Administration Using Physiologically Based Pharmacokinetic Modeling

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