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Relationship between glycine transporter 1 inhibition as measured with positron emission tomography and changes in cognitive performances in nonhuman primates

Neuropsychopharmacology (New York, N.Y.), 2014-11, Vol.39 (12), p.2742-2749

2014

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Characterization of a CNS penetrant, selective M 1 muscarinic receptor agonist, 77‐LH‐28‐1

British journal of pharmacology, 2008-07, Vol.154 (5), p.1104-1115

2008

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Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes

Neuropharmacology, 2001-07, Vol.41 (1), p.88-96

2001

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Identification and evaluation of [11C]GSK931145 as a novel ligand for imaging the type 1 glycine transporter with positron emission tomography

Synapse (New York, N.Y.), 2010-07, Vol.64 (7), p.542-549

2010

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Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77‐LH‐28‐1

British journal of pharmacology, 2008-07, Vol.154 (5), p.1104-1115

2008

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[ 11C]GSK931145: A new pet ligand for glycine transporter 1

NeuroImage (Orlando, Fla.), 2008, Vol.41, p.T21-T21

2008

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Forearm rotation alters interosseous ligament strain distribution

The Journal of hand surgery (American ed.), 2000-11, Vol.25 (6), p.1058-1063

2000

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Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent

Bioorganic & medicinal chemistry letters, 1999-01, Vol.9 (2), p.285-290

1999

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Characterization of the binding of [125I]‐human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor

British journal of pharmacology, 2000-10, Vol.131 (4), p.683-688

2000

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Profile of SB‐204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures

British journal of pharmacology, 1997-08, Vol.121 (8), p.1679-1686

1997

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Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

Journal of medicinal chemistry, 1996-11, Vol.39 (23), p.4537-4539

1996

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Use of the radioligand [ 125I]-SB-217644 in the characterisation and solubilisation of the novel binding site for the anticonvulsant SB-204269 in rat brain membranes and cell lines

Neuropharmacology, 2000-09, Vol.39 (12), p.2457-2463

2000

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Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes

British journal of pharmacology, 1997-08, Vol.121 (8), p.1687-1691

1997

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Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity

Bioorganic & medicinal chemistry letters, 1998-10, Vol.8 (20), p.2903-2906

1998

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Characterisation of the binding of [3H]‐SB‐674042, a novel nonpeptide antagonist, to the human orexin‐1 receptor

British journal of pharmacology, 2004-01, Vol.141 (2), p.340-346

2004

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Solubilisation of A Novel Anticonvulsant Binding Site From Pig Cortical Membranes

Journal of receptors and signal transduction, 2000, Vol.20 (2-3), p.167-186

2000

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Probing the Molecular Mechanism of Interaction between 4- n -Butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the Muscarinic M 1 Receptor: Direct Pharmacological Evidence That AC-42 Is an Allosteric Agonist

Molecular pharmacology, 2006-01, Vol.69 (1), p.236-246

2006

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Conformational preference of the 6-acetyl group in novel anticonvulsant trans 4S-benzamido-benzo[b]pyran-3R-ols

Bioorganic & medicinal chemistry letters, 1997-06, Vol.7 (12), p.1573-1576

1997

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Meeting Highlights: 17th Annual Meeting of the European Neuroscience Association 4-8 September, 1994, Vienna, Austria

Expert opinion on investigational drugs, 1994-12, Vol.3 (12), p.1331-1332

Herdon, H

1994

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Changes in hypothalamic dopamine D-2 receptors during sexual maturation in male and female rats

Brain research, 1985-09, Vol.343 (1), p.151-153

1985

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Effect of testosterone on gonadotrophin-releasing hormone receptors in the castrated rat: preliminary evidence for a stimulatory effect of testosterone on gonadotrophin function in the male rat

Journal of endocrinology, 1986-03, Vol.108 (3), p.441-449

1986

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SB 201823-A, a neuronal Ca2+ antagonist is neuroprotective in two models of cerebral ischaemia

Neuropharmacology, 1993-11, Vol.32 (11), p.1249-1257

1993

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Studies on the control of gonadotrophin release in the gonadectomized male rat: evidence for a lack of involvement of the hypothalamic noradrenergic system in the long-term castrated rat

Journal of endocrinology, 1984-02, Vol.100 (2), p.235-244

1984

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N-ethylmaleimide inactivates adenylate cyclase-coupled but not presynaptic striatal d-2 receptor systems

European journal of pharmacology, 1988-09, Vol.154 (1), p.115-116

Herdon, Hugh

1988

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α- and β-adrenergic binding sites in sheep cerebral cortex: Characterisation, effects of photoperiod and treatment with estrogen/progesterone

Brain research bulletin, 1983, Vol.10 (1), p.159-161

1983

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Relationship between glycine transporter 1 inhibition as measured with positron emission tomography and changes in cognitive performances in nonhuman primates

Characterization of a CNS penetrant, selective M 1 muscarinic receptor agonist, 77‐LH‐28‐1

Pharmacological assessment of the role of the glycine transporter GlyT-1 in mediating high-affinity glycine uptake by rat cerebral cortex and cerebellum synaptosomes

Identification and evaluation of [11C]GSK931145 as a novel ligand for imaging the type 1 glycine transporter with positron emission tomography

Characterization of a CNS penetrant, selective M1 muscarinic receptor agonist, 77‐LH‐28‐1

[ 11C]GSK931145: A new pet ligand for glycine transporter 1

Forearm rotation alters interosseous ligament strain distribution

Identification of (-)-cis-6-acetyl-4S-(3-chloro-4-fluoro-benzoylamino)-3,4-dihydro-2,2-dimethyl-2H-benzo[b]pyran-3S-ol as a potential antimigraine agent

Characterization of the binding of [125I]‐human prolactin releasing peptide (PrRP) to GPR10, a novel G protein coupled receptor

Profile of SB‐204269, a mechanistically novel anticonvulsant drug, in rat models of focal and generalized epileptic seizures

Synthesis of Novel trans-4-(Substituted-benzamido)-3,4-dihydro-2H-benzo[b]pyran-3-ol Derivatives as Potential Anticonvulsant Agents with a Distinctive Binding Profile

Use of the radioligand [ 125I]-SB-217644 in the characterisation and solubilisation of the novel binding site for the anticonvulsant SB-204269 in rat brain membranes and cell lines

Characterization of the binding of [3H]‐SB‐204269, a radiolabelled form of the new anticonvulsant SB‐204269, to a novel binding site in rat brain membranes

Identification of a series of 1,2,3,4-tetrahydroisoquinolinyl- benzamides with potential anticonvulsant activity

Characterisation of the binding of [3H]‐SB‐674042, a novel nonpeptide antagonist, to the human orexin‐1 receptor

Solubilisation of A Novel Anticonvulsant Binding Site From Pig Cortical Membranes

Probing the Molecular Mechanism of Interaction between 4- n -Butyl-1-[4-(2-methylphenyl)-4-oxo-1-butyl]-piperidine (AC-42) and the Muscarinic M 1 Receptor: Direct Pharmacological Evidence That AC-42 Is an Allosteric Agonist

Conformational preference of the 6-acetyl group in novel anticonvulsant trans 4S-benzamido-benzo[b]pyran-3R-ols

Meeting Highlights: 17th Annual Meeting of the European Neuroscience Association 4-8 September, 1994, Vienna, Austria

Changes in hypothalamic dopamine D-2 receptors during sexual maturation in male and female rats

Effect of testosterone on gonadotrophin-releasing hormone receptors in the castrated rat: preliminary evidence for a stimulatory effect of testosterone on gonadotrophin function in the male rat

SB 201823-A, a neuronal Ca2+ antagonist is neuroprotective in two models of cerebral ischaemia

Studies on the control of gonadotrophin release in the gonadectomized male rat: evidence for a lack of involvement of the hypothalamic noradrenergic system in the long-term castrated rat

N-ethylmaleimide inactivates adenylate cyclase-coupled but not presynaptic striatal d-2 receptor systems

α- and β-adrenergic binding sites in sheep cerebral cortex: Characterisation, effects of photoperiod and treatment with estrogen/progesterone

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