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Gene Editing Rescues In vitro T Cell Development of RAG2-Deficient Induced Pluripotent Stem Cells in an Artificial Thymic Organoid System

Journal of clinical immunology, 2021-07, Vol.41 (5), p.852-862

2021

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THEMIS: a critical TCR signal regulator for ligand discrimination

Current opinion in immunology, 2015-04, Vol.33, p.86-92

2015

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Regulation of thymocyte trafficking by Tagap, a GAP domain protein linked to human autoimmunity

Science signaling, 2018-06, Vol.11 (534)

2018

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Autoimmune-associated PTPN22 R620W Variation Reduces Phosphorylation of Lymphoid Phosphatase on an Inhibitory Tyrosine Residue

The Journal of biological chemistry, 2010-08, Vol.285 (34), p.26506-26518

2010

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Recruitment of the Actin-binding Protein HIP-55 to the Immunological Synapse Regulates T Cell Receptor Signaling and Endocytosis

The Journal of biological chemistry, 2004-04, Vol.279 (15), p.15550-15560

2004

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TCR Signal Strength and T Cell Development

Annual review of cell and developmental biology, 2016-10, Vol.32 (1), p.327-348

2016

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Protein arginine methylation in lymphocyte signaling

Current Opinion in Immunology, 2006-06, Vol.18 (3), p.321-328

2006

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Role of Fyn in the Rearrangement of Tubulin Cytoskeleton Induced through TCR

Journal of Immunology, 2006-04, Vol.176 (7), p.4201-4207

2006

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Quantitative Dynamics of Phosphoproteome: The Devil Is in the Details

Analytical chemistry (Washington), 2012-10, Vol.84 (20), p.8431-8436

2012

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Fyn and ZAP-70 Are Required for Vav Phosphorylation in T Cells Stimulated by Antigen-presenting Cells

The Journal of biological chemistry, 1998-11, Vol.273 (48), p.31932-31938

1998

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Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

Proceedings of the National Academy of Sciences - PNAS, 2016-09, Vol.113 (37), p.E5454-E5463

2016

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Fine-tuning T cell receptor signaling to control T cell development

Trends in immunology, 2014-07, Vol.35 (7), p.311-318

2014

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A THEMIS:SHP1 complex promotes T-cell survival

The EMBO journal, 2015-02, Vol.34 (3), p.393-409

2015

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Cognate MHC–TCR interaction leads to apoptosis of antigen-presenting cells

Journal of leukocyte biology, 2004-06, Vol.75 (6), p.1036-1044

2004

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An Ig Transmembrane Domain Motif Improves the Function of TCRs Transduced in Human T Cells: Implications for Immunotherapy

Journal of immunotherapy (1997), 2019-05, Vol.42 (4), p.97-109

2019

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Altered Peptide Ligands Induce Quantitatively but not Qualitatively Different Intracellular Signals in Primary Thymocytes

Proceedings of the National Academy of Sciences - PNAS, 1998-07, Vol.95 (14), p.8193-8198

1998

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The late endosomal transporter CD222 directs the spatial distribution and activity of Lck

The Journal of immunology (1950), 2014-09, Vol.193 (6), p.2718-2732

2014

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SHP1‐ing thymic selection

European journal of immunology, 2016-09, Vol.46 (9), p.2091-2094

2016

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T Cell Receptor (TCR)-induced Tyrosine Phosphorylation Dynamics Identifies THEMIS as a New TCR Signalosome Component

The Journal of biological chemistry, 2011-03, Vol.286 (9), p.7535-7547

2011

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Activation of Zap-70 Tyrosine Kinase Due to a Structural Rearrangement Induced by Tyrosine Phosphorylation and/or ITAM Binding

Biochemistry (Easton), 2000-03, Vol.39 (10), p.2784-2791

2000

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Kidins220/ARMS associates with B-Raf and the TCR, promoting sustained Erk signaling in T cells

The Journal of immunology (1950), 2013-03, Vol.190 (5), p.1927-1935

2013

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A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76

The Journal of experimental medicine, 2007-03, Vol.204 (3), p.681-691

2007

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CD28 costimulatory signal induces protein arginine methylation in T cells

The Journal of experimental medicine, 2005-08, Vol.202 (3), p.371-377

2005

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A conserved polylysine motif in CD86 cytoplasmic tail is necessary for cytoskeletal association and effective co-stimulation

Biochemical and biophysical research communications, 2012-06, Vol.423 (2), p.301-307

2012

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CD28 affects the earliest signaling events generated by TCR engagement

European journal of immunology, 1998-07, Vol.28 (7), p.2131-2142

1998

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Gene Editing Rescues In vitro T Cell Development of RAG2-Deficient Induced Pluripotent Stem Cells in an Artificial Thymic Organoid System

THEMIS: a critical TCR signal regulator for ligand discrimination

Regulation of thymocyte trafficking by Tagap, a GAP domain protein linked to human autoimmunity

Autoimmune-associated PTPN22 R620W Variation Reduces Phosphorylation of Lymphoid Phosphatase on an Inhibitory Tyrosine Residue

Recruitment of the Actin-binding Protein HIP-55 to the Immunological Synapse Regulates T Cell Receptor Signaling and Endocytosis

TCR Signal Strength and T Cell Development

Protein arginine methylation in lymphocyte signaling

Role of Fyn in the Rearrangement of Tubulin Cytoskeleton Induced through TCR

Quantitative Dynamics of Phosphoproteome: The Devil Is in the Details

Fyn and ZAP-70 Are Required for Vav Phosphorylation in T Cells Stimulated by Antigen-presenting Cells

Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination

Fine-tuning T cell receptor signaling to control T cell development

A THEMIS:SHP1 complex promotes T-cell survival

Cognate MHC–TCR interaction leads to apoptosis of antigen-presenting cells

An Ig Transmembrane Domain Motif Improves the Function of TCRs Transduced in Human T Cells: Implications for Immunotherapy

Altered Peptide Ligands Induce Quantitatively but not Qualitatively Different Intracellular Signals in Primary Thymocytes

The late endosomal transporter CD222 directs the spatial distribution and activity of Lck

SHP1‐ing thymic selection

T Cell Receptor (TCR)-induced Tyrosine Phosphorylation Dynamics Identifies THEMIS as a New TCR Signalosome Component

Activation of Zap-70 Tyrosine Kinase Due to a Structural Rearrangement Induced by Tyrosine Phosphorylation and/or ITAM Binding

Kidins220/ARMS associates with B-Raf and the TCR, promoting sustained Erk signaling in T cells

A novel pathway down-modulating T cell activation involves HPK-1-dependent recruitment of 14-3-3 proteins on SLP-76

CD28 costimulatory signal induces protein arginine methylation in T cells

A conserved polylysine motif in CD86 cytoplasmic tail is necessary for cytoskeletal association and effective co-stimulation

CD28 affects the earliest signaling events generated by TCR engagement

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