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The Allostery Model of TCR Regulation

The Journal of immunology (1950), 2017-01, Vol.198 (1), p.47-52

2017

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A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

Nature communications, 2018-03, Vol.9 (1), p.1080-16, Article 1080

2018

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Editorial: Cytoskeletal Regulation of Immune Response

Frontiers in cell and developmental biology, 2021-11, Vol.9, p.791327-791327

2021

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Small molecule AX-024 targets T cell receptor signaling by disrupting CD3ε-Nck interaction

The Journal of biological chemistry, 2020-07, Vol.295 (29), p.10076-10076

2020

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Flow cytometry detection of sustained humoral immune response (IgG + IgA) against native spike glycoprotein in asymptomatic/mild SARS-CoV-2 infection

Scientific reports, 2021-05, Vol.11 (1), p.10716-10716, Article 10716

2021

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The TCR is an allosterically regulated macromolecular machinery changing its conformation while working

Immunological reviews, 2019-09, Vol.291 (1), p.8-25

2019

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Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response

The Journal of experimental medicine, 2005-08, Vol.202 (4), p.493-503

2005

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The immunological synapse: a cause or consequence of T‐cell receptor triggering?

Immunology, 2011-08, Vol.133 (4), p.420-425

2011

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Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS‐CoV‐2 spike protein

EMBO molecular medicine, 2021-03, Vol.13 (3), p.e13549-n/a

2021

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Physiological and therapeutic relevance of T cell receptor-mediated antigen trogocytosis

Biomedical Journal, 2023-07, p.100630-100630, Article 100630

2023

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ACE2 Serum Levels as Predictor of Infectability and Outcome in COVID-19

Frontiers in immunology, 2022-03, Vol.13, p.836516-836516

2022

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Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia

Molecular cancer, 2022-02, Vol.21 (1), p.35-35, Article 35

2022

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Organization of the resting TCR in nanoscale oligomers

Immunological reviews, 2013-01, Vol.251 (1), p.13-20

2013

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An Optimized Single Nucleotide Polymorphism-Based Detection Method Suggests That Allelic Variants in the 3' Untranslated Region of RRAS2 Correlate with Treatment Response in Chronic Lymphocytic Leukemia Patients

Cancers, 2023-01, Vol.15 (3), p.644

2023

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Vaccine Type-, Age- and Past Infection-Dependence of the Humoral Response to SARS-CoV-2 Spike S Protein

Frontiers in immunology, 2022-02, Vol.13, p.809285-809285

2022

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Mice Overexpressing Wild-Type RRAS2 Are a Novel Model for Preclinical Testing of Anti-Chronic Lymphocytic Leukemia Therapies

Cancers, 2023-12, Vol.15 (24), p.5817

2023

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Conventional CD4 + T cells present bacterial antigens to induce cytotoxic and memory CD8 + T cell responses

Nature communications, 2017-11, Vol.8 (1), p.1591-11, Article 1591

2017

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T Cell Receptor Internalization from the Immunological Synapse Is Mediated by TC21 and RhoG GTPase-Dependent Phagocytosis

Immunity (Cambridge, Mass.), 2011-08, Vol.35 (2), p.208-222

2011

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MTOC translocation modulates IS formation and controls sustained T cell signaling

The Journal of cell biology, 2008-09, Vol.182 (5), p.951-962

2008

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Editorial: Nck has a knack for T cell differentiation

Journal of leukocyte biology, 2015-09, Vol.98 (3), p.297-298

2015

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Aurora A drives early signalling and vesicle dynamics during T-cell activation

Nature communications, 2016-04, Vol.7 (1), p.11389-11389, Article 11389

2016

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Antigen phagocytosis by B cells is required for a potent humoral response

EMBO reports, 2018-09, Vol.19 (9), p.n/a

2018

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Mutation of the Polyproline Sequence in CD3ε Evidences TCR Signaling Requirements for Differentiation and Function of Pro-Inflammatory Tγδ17 Cells

Frontiers in immunology, 2022-03, Vol.13, p.799919-799919

2022

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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors

Oncogene, 2023-01, Vol.42 (5), p.389-405

2023

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Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination

Frontiers in immunology, 2023-04, Vol.14, p.1157263-1157263

2023

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The Allostery Model of TCR Regulation

A non-conserved amino acid variant regulates differential signalling between human and mouse CD28

Editorial: Cytoskeletal Regulation of Immune Response

Small molecule AX-024 targets T cell receptor signaling by disrupting CD3ε-Nck interaction

Flow cytometry detection of sustained humoral immune response (IgG + IgA) against native spike glycoprotein in asymptomatic/mild SARS-CoV-2 infection

The TCR is an allosterically regulated macromolecular machinery changing its conformation while working

Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response

The immunological synapse: a cause or consequence of T‐cell receptor triggering?

Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS‐CoV‐2 spike protein

Physiological and therapeutic relevance of T cell receptor-mediated antigen trogocytosis

ACE2 Serum Levels as Predictor of Infectability and Outcome in COVID-19

Overexpression of wild type RRAS2, without oncogenic mutations, drives chronic lymphocytic leukemia

Organization of the resting TCR in nanoscale oligomers

An Optimized Single Nucleotide Polymorphism-Based Detection Method Suggests That Allelic Variants in the 3' Untranslated Region of RRAS2 Correlate with Treatment Response in Chronic Lymphocytic Leukemia Patients

Vaccine Type-, Age- and Past Infection-Dependence of the Humoral Response to SARS-CoV-2 Spike S Protein

Mice Overexpressing Wild-Type RRAS2 Are a Novel Model for Preclinical Testing of Anti-Chronic Lymphocytic Leukemia Therapies

Conventional CD4 + T cells present bacterial antigens to induce cytotoxic and memory CD8 + T cell responses

T Cell Receptor Internalization from the Immunological Synapse Is Mediated by TC21 and RhoG GTPase-Dependent Phagocytosis

MTOC translocation modulates IS formation and controls sustained T cell signaling

Editorial: Nck has a knack for T cell differentiation

Aurora A drives early signalling and vesicle dynamics during T-cell activation

Antigen phagocytosis by B cells is required for a potent humoral response

Mutation of the Polyproline Sequence in CD3ε Evidences TCR Signaling Requirements for Differentiation and Function of Pro-Inflammatory Tγδ17 Cells

Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors

Decreased breadth of the antibody response to the spike protein of SARS-CoV-2 after repeated vaccination

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