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Mechanism and molecular basis for the sodium channel subtype specificity of µ‐conopeptide CnIIIC

British journal of pharmacology, 2012-10, Vol.167 (3), p.576-586

2012

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Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

The Journal of biological chemistry, 2020-01, Vol.295 (5), p.1315-1327

2020

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The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5

British journal of pharmacology, 2014-01, Vol.171 (2), p.427

2014

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International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel

Pharmacological reviews, 2015-01, Vol.67 (1), p.1-35

2015

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The Concise Guide to PHARMACOLOGY 2015/16: Voltage‐gated ion channels

British journal of pharmacology, 2015-12, Vol.172 (24), p.5904-5941

2015

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Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade

The Journal of general physiology, 2007-02, Vol.129 (2), p.161-173

2007

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Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (17), p.6704

2012

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Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways

American journal of respiratory and critical care medicine, 2016-09, Vol.194 (6), p.701-710

2016

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Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

Proceedings of the National Academy of Sciences - PNAS, 2017-03, Vol.114 (10), p.E1857-E1865

2017

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International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

Pharmacological reviews, 2005-12, Vol.57 (4), p.397

2005

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Subicular pyramidal neurons gate drug resistance in temporal lobe epilepsy

Annals of neurology, 2019-10, Vol.86 (4), p.626-640

2019

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Subtype‐selective targeting of voltage‐gated sodium channels

British journal of pharmacology, 2009-11, Vol.158 (6), p.1413-1425

2009

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Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects

Frontiers in bioscience (Landmark. Print), 2013-01, Vol.18 (2), p.572

2013

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Loss-of-Function of the Voltage-Gated Sodium Channel NaV1.5 (Channelopathies) in Patients With Irritable Bowel Syndrome

Gastroenterology (New York, N.Y. 1943), 2014-06, Vol.146 (7), p.1659-1668

2014

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Variability in the efficacy of a standardized antenatal steroid treatment was independent of maternal or fetal plasma drug levels: evidence from a sheep model of pregnancy

American journal of obstetrics and gynecology, 2020-12, Vol.223 (6), p.921.e1-921.e10

2020

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Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain

The Journal of biological chemistry, 2016-07, Vol.291 (27), p.13974-13986

2016

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Differential effects on fast and slow spindle activity, and the sleep slow oscillation in humans with carbamazepine and flunarizine to antagonize voltage-dependent Na+ and Ca2+ channel activity

Sleep (New York, N.Y.), 2013-06, Vol.36 (6), p.905-911

2013

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Naja atra venom peptide reduces pain by selectively blocking the voltage-gated sodium channel Nav1.8

The Journal of biological chemistry, 2019-05, Vol.294 (18), p.7324-7334

2019

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Inhibition of voltage‐gated Na+ currents in sensory neurones by the sea anemone toxin APETx2

British journal of pharmacology, 2012-04, Vol.165 (7), p.2167-2177

2012

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Bidirectional influence of sodium channel activation on NMDA receptor–dependent cerebrocortical neuron structural plasticity

Proceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (48), p.19840-19845

2012

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The cardiac persistent sodium current: an appealing therapeutic target?

British journal of pharmacology, 2008-03, Vol.153 (6), p.1133-1142

Saint, D A

2008

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Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7

The Journal of biological chemistry, 2020-04, Vol.295 (15), p.5067-5080

2020

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Oxaliplatin induces hyperexcitability at motor and autonomic neuromuscular junctions through effects on voltage‐gated sodium channels

British journal of pharmacology, 2005-12, Vol.146 (7), p.1027-1039

2005

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Developmental Neurotoxicity of Pyrethroid Insecticides: Critical Review and Future Research Needs

Environmental health perspectives, 2005-02, Vol.113 (2), p.123-136

2005

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Potassium softens vascular endothelium and increases nitric oxide release

Proceedings of the National Academy of Sciences - PNAS, 2009-02, Vol.106 (8), p.2829-2834

2009

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Mechanism and molecular basis for the sodium channel subtype specificity of µ‐conopeptide CnIIIC

Comprehensive engineering of the tarantula venom peptide huwentoxin-IV to inhibit the human voltage-gated sodium channel hNa v 1.7

The opioid methadone induces a local anaesthetic-like inhibition of the cardiac Na⁺ channel, Na(v)1.5

International Union of Basic and Clinical Pharmacology. XCI. structure, function, and pharmacology of acid-sensing ion channels and the epithelial Na+ channel

The Concise Guide to PHARMACOLOGY 2015/16: Voltage‐gated ion channels

Gain-of-function mutations in the MEC-4 DEG/ENaC sensory mechanotransduction channel alter gating and drug blockade

Anticancer drug oxaliplatin induces acute cooling-aggravated neuropathy via sodium channel subtype Na(V)1.6-resurgent and persistent current

Inhibition of Protease-Epithelial Sodium Channel Signaling Improves Mucociliary Function in Cystic Fibrosis Airways

Mapping of voltage sensor positions in resting and inactivated mammalian sodium channels by LRET

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels

Subicular pyramidal neurons gate drug resistance in temporal lobe epilepsy

Subtype‐selective targeting of voltage‐gated sodium channels

Scorpion beta-toxins and voltage-gated sodium channels: interactions and effects

Loss-of-Function of the Voltage-Gated Sodium Channel NaV1.5 (Channelopathies) in Patients With Irritable Bowel Syndrome

Variability in the efficacy of a standardized antenatal steroid treatment was independent of maternal or fetal plasma drug levels: evidence from a sheep model of pregnancy

Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of Pain

Differential effects on fast and slow spindle activity, and the sleep slow oscillation in humans with carbamazepine and flunarizine to antagonize voltage-dependent Na+ and Ca2+ channel activity

Naja atra venom peptide reduces pain by selectively blocking the voltage-gated sodium channel Nav1.8

Inhibition of voltage‐gated Na+ currents in sensory neurones by the sea anemone toxin APETx2

Bidirectional influence of sodium channel activation on NMDA receptor–dependent cerebrocortical neuron structural plasticity

The cardiac persistent sodium current: an appealing therapeutic target?

Manipulation of a spider peptide toxin alters its affinity for lipid bilayers and potency and selectivity for voltage-gated sodium channel subtype 1.7

Oxaliplatin induces hyperexcitability at motor and autonomic neuromuscular junctions through effects on voltage‐gated sodium channels

Developmental Neurotoxicity of Pyrethroid Insecticides: Critical Review and Future Research Needs

Potassium softens vascular endothelium and increases nitric oxide release

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