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Early antibody therapy can induce long-lasting immunity to SHIV

Nature (London), 2017-03, Vol.543 (7646), p.559-563

2017

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Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys

Nature (London), 2018-11, Vol.563 (7731), p.360-364

2018

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Sustained virologic control in SIV⁺ macaques after antiretroviral and α₄β₇ antibody therapy

Science (American Association for the Advancement of Science), 2016-10, Vol.354 (6309), p.197-202

2016

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Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques

Nature medicine, 2016-04, Vol.22 (4), p.362-368

2016

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CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

Immunity (Cambridge, Mass.), 2017-10, Vol.47 (4), p.776-788.e5

2017

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Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

Nature (London), 2014-07, Vol.511 (7511), p.601-605

2014

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CD8+ Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy

Immunity (Cambridge, Mass.), 2016-09, Vol.45 (3), p.656-668

2016

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The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

PLoS pathogens, 2020-03, Vol.16 (3), p.e1008339-e1008339

2020

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The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections

Cell host & microbe, 2019-07, Vol.26 (1), p.73-85.e4

2019

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Brain macrophages harbor latent, infectious simian immunodeficiency virus

AIDS (London), 2019-12, Vol.33 Suppl 2 (Supplement 2), p.S181-S188

2019

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Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques

Nature communications, 2021-03, Vol.12 (1), p.1474-1474, Article 1474

2021

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Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy

Science translational medicine, 2017-08, Vol.9 (405)

2017

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Mechanisms of CD8+ T cell‐mediated suppression of HIV/SIV replication

European journal of immunology, 2018-06, Vol.48 (6), p.898-914

2018

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Chronic Immune Activation in TB/HIV Co-infection

Trends in microbiology (Regular ed.), 2020-08, Vol.28 (8), p.619-632

2020

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Long-acting capsid inhibitor protects macaques from repeat SHIV challenges

Nature (London), 2022-01, Vol.601 (7894), p.612-616

2022

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Alterations of the gut bacterial microbiota in rhesus macaques with SIV infection and on short- or long-term antiretroviral therapy

Scientific reports, 2020-11, Vol.10 (1), p.19056-19056, Article 19056

2020

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Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a Mycobacterium tuberculosis/SIV coinfection model

The Journal of clinical investigation, 2022-02, Vol.132 (3), p.1-14

2022

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Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes

PLoS pathogens, 2018-02, Vol.14 (2), p.e1006902

2018

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IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques

Nature communications, 2021-05, Vol.12 (1), p.2866-12, Article 2866

2021

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ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment

Journal of virology, 2018-02, Vol.92 (3)

2018

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Pharmacological Modulation of the Wnt/β-Catenin Pathway Inhibits Proliferation and Promotes Differentiation of Long-Lived Memory CD4 + T Cells in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques

Journal of virology, 2019-12, Vol.94 (1)

2019

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Exacerbated AIDS Progression by PD-1 Blockade during Therapeutic Vaccination in Chronically Simian Immunodeficiency Virus-Infected Rhesus Macaques after Interruption of Antiretroviral Therapy

Journal of virology, 2022-02, Vol.96 (3), p.e0178521-e0178521

2022

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An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes

The Journal of immunology (1950), 2020-06, Vol.204 (12), p.3315-3328

2020

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A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro , Ex Vivo , and In Vivo Antiviral Activity

Journal of virology, 2017-06, Vol.91 (11)

2017

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Early antibody therapy can induce long-lasting immunity to SHIV

Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys

Sustained virologic control in SIV⁺ macaques after antiretroviral and α₄β₇ antibody therapy

Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques

CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

Type I interferon responses in rhesus macaques prevent SIV infection and slow disease progression

CD8+ Lymphocytes Are Required for Maintaining Viral Suppression in SIV-Infected Macaques Treated with Short-Term Antiretroviral Therapy

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections

Brain macrophages harbor latent, infectious simian immunodeficiency virus

Persistence of viral RNA in lymph nodes in ART-suppressed SIV/SHIV-infected Rhesus Macaques

Inflammatory monocytes expressing tissue factor drive SIV and HIV coagulopathy

Mechanisms of CD8+ T cell‐mediated suppression of HIV/SIV replication

Chronic Immune Activation in TB/HIV Co-infection

Long-acting capsid inhibitor protects macaques from repeat SHIV challenges

Alterations of the gut bacterial microbiota in rhesus macaques with SIV infection and on short- or long-term antiretroviral therapy

Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a Mycobacterium tuberculosis/SIV coinfection model

Treatment with native heterodimeric IL-15 increases cytotoxic lymphocytes and reduces SHIV RNA in lymph nodes

IL-21 and IFNα therapy rescues terminally differentiated NK cells and limits SIV reservoir in ART-treated macaques

ALT-803 Transiently Reduces Simian Immunodeficiency Virus Replication in the Absence of Antiretroviral Treatment

Pharmacological Modulation of the Wnt/β-Catenin Pathway Inhibits Proliferation and Promotes Differentiation of Long-Lived Memory CD4 + T Cells in Antiretroviral Therapy-Suppressed Simian Immunodeficiency Virus-Infected Macaques

Exacerbated AIDS Progression by PD-1 Blockade during Therapeutic Vaccination in Chronically Simian Immunodeficiency Virus-Infected Rhesus Macaques after Interruption of Antiretroviral Therapy

Type I IFN signaling blockade by a PASylated antagonist during chronic SIV infection suppresses specific inflammatory pathways but does not alter T cell activation or virus replication

An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes

A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro , Ex Vivo , and In Vivo Antiviral Activity

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