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Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys

Nature (London), 2018-11, Vol.563 (7731), p.360-364

2018

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Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques

Nature medicine, 2016-04, Vol.22 (4), p.362-368

2016

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CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

Immunity (Cambridge, Mass.), 2017-10, Vol.47 (4), p.776-788.e5

2017

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SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques

Journal of virology, 2020-10, Vol.94 (21)

2020

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The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

PLoS pathogens, 2020-03, Vol.16 (3), p.e1008339-e1008339

2020

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The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections

Cell host & microbe, 2019-07, Vol.26 (1), p.73-85.e4

2019

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Brain macrophages harbor latent, infectious simian immunodeficiency virus

AIDS (London), 2019-12, Vol.33 Suppl 2 (Supplement 2), p.S181-S188

2019

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Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide

Cell, 2022-01, Vol.185 (1), p.131-144.e18

2022

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Antiretroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV coinfection model

The Journal of clinical investigation, 2020-10, Vol.130 (10), p.5171-5179

2020

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Monocyte/macrophages and their role in HIV neuropathogenesis

Immunological reviews, 2013-07, Vol.254 (1), p.102-113

2013

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Lentiviral Infections Persist in Brain despite Effective Antiretroviral Therapy and Neuroimmune Activation

mBio, 2021-12, Vol.12 (6), p.e0278421-e0278421

2021

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Mechanisms of CD8+ T cell‐mediated suppression of HIV/SIV replication

European journal of immunology, 2018-06, Vol.48 (6), p.898-914

2018

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Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans

PLoS pathogens, 2019-07, Vol.15 (7), p.e1007869

2019

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Chronic Immune Activation in TB/HIV Co-infection

Trends in microbiology (Regular ed.), 2020-08, Vol.28 (8), p.619-632

2020

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Dysbiotic bacteria translocate in progressive SIV infection

Mucosal immunology, 2015-09, Vol.8 (5), p.1009-1020

2015

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Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication

The Journal of clinical investigation, 2014-06, Vol.124 (6), p.2802-2806

2014

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Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART

PLoS pathogens, 2018-02, Vol.14 (2), p.e1006871

2018

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Early antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8 + T-cells

Nature communications, 2024-01, Vol.15 (1), p.178-178, Article 178

2024

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The TLR7 agonist vesatolimod induced a modest delay in viral rebound in HIV controllers after cessation of antiretroviral therapy

Science translational medicine, 2021-06, Vol.13 (599)

2021

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An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes

The Journal of immunology (1950), 2020-06, Vol.204 (12), p.3315-3328

2020

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A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro , Ex Vivo , and In Vivo Antiviral Activity

Journal of virology, 2017-06, Vol.91 (11)

2017

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Lymph nodes harbor viral reservoirs that cause rebound of plasma viremia in SIV-infected macaques upon cessation of combined antiretroviral therapy

Virology (New York, N.Y.), 2012-02, Vol.423 (2), p.107-118

2012

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Durable Protection from Vaginal Simian-Human Immunodeficiency Virus Infection in Macaques by Tenofovir Gel and Its Relationship to Drug Levels in Tissue

Journal of Virology, 2012-01, Vol.86 (2), p.718-725

2012

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Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques

Science (American Association for the Advancement of Science), 2024-03, Vol.383 (6687), p.1104-1111

2024

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Antiretroviral Therapy Ameliorates Simian Immunodeficiency Virus–Associated Myocardial Inflammation by Dampening Interferon Signaling and Pathogen Response in the Heart

The Journal of infectious diseases, 2023-08, Vol.228 (3), p.276-280

2023

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Antibody and TLR7 agonist delay viral rebound in SHIV-infected monkeys

Early short-term treatment with neutralizing human monoclonal antibodies halts SHIV infection in infant macaques

CTLA-4+PD-1− Memory CD4+ T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques

The human IL-15 superagonist N-803 promotes migration of virus-specific CD8+ T and NK cells to B cell follicles but does not reverse latency in ART-suppressed, SHIV-infected macaques

The Landscape of Persistent Viral Genomes in ART-Treated SIV, SHIV, and HIV-2 Infections

Brain macrophages harbor latent, infectious simian immunodeficiency virus

Efficient treatment and pre-exposure prophylaxis in rhesus macaques by an HIV fusion-inhibitory lipopeptide

Antiretroviral therapy does not reduce tuberculosis reactivation in a tuberculosis-HIV coinfection model

Monocyte/macrophages and their role in HIV neuropathogenesis

Lentiviral Infections Persist in Brain despite Effective Antiretroviral Therapy and Neuroimmune Activation

Mechanisms of CD8+ T cell‐mediated suppression of HIV/SIV replication

Clonal expansion of SIV-infected cells in macaques on antiretroviral therapy is similar to that of HIV-infected cells in humans

Chronic Immune Activation in TB/HIV Co-infection

Dysbiotic bacteria translocate in progressive SIV infection

Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication

Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART

Early antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8 + T-cells

The TLR7 agonist vesatolimod induced a modest delay in viral rebound in HIV controllers after cessation of antiretroviral therapy

An SAMT-247 Microbicide Provides Potent Protection against Intravaginal Simian Immunodeficiency Virus Infection of Rhesus Macaques, whereas an Added Vaccine Component Elicits Mixed Outcomes

A Lipopeptide HIV-1/2 Fusion Inhibitor with Highly Potent In Vitro , Ex Vivo , and In Vivo Antiviral Activity

Lymph nodes harbor viral reservoirs that cause rebound of plasma viremia in SIV-infected macaques upon cessation of combined antiretroviral therapy

Durable Protection from Vaginal Simian-Human Immunodeficiency Virus Infection in Macaques by Tenofovir Gel and Its Relationship to Drug Levels in Tissue

Induction of durable remission by dual immunotherapy in SHIV-infected ART-suppressed macaques

Antiretroviral Therapy Ameliorates Simian Immunodeficiency Virus–Associated Myocardial Inflammation by Dampening Interferon Signaling and Pathogen Response in the Heart

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