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Tau and neurofilament light‐chain as fluid biomarkers in spinocerebellar ataxia type 3

European journal of neurology, 2022-08, Vol.29 (8), p.2439-2452

2022

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Kynurenine pathway dysfunction in the pathophysiology and treatment of depression: Evidences from animal and human studies

Journal of psychiatric research, 2015-09, Vol.68, p.316-328

2015

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Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

Nature neuroscience, 2009-10, Vol.12 (10), p.1300-1307

2009

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Astrocyte-derived clusterin suppresses amyloid formation in vivo

Molecular neurodegeneration, 2020-11, Vol.15 (1), p.71-14, Article 71

2020

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Progranulin regulates neuronal outgrowth independent of sortilin

Molecular neurodegeneration, 2012-07, Vol.7 (1), p.33-33, Article 33

2012

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Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

Neuron (Cambridge, Mass.), 2014-09, Vol.83 (5), p.1043-1050

2014

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Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

Acta neuropathologica, 2014-10, Vol.128 (4), p.505-524

2014

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TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor

Human molecular genetics, 2016-02, Vol.25 (3), p.534-545

2016

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Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

Molecular neurodegeneration, 2020-03, Vol.15 (1), p.21-19, Article 21

2020

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Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Molecular neurodegeneration, 2019-02, Vol.14 (1), p.9-15, Article 9

2019

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Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation

Acta neuropathologica communications, 2020-12, Vol.8 (1), p.210-210, Article 210

2020

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Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila

Alzheimer's research & therapy, 2020-10, Vol.12 (1), p.132-12, Article 132

2020

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The extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivo

Brain research, 2016-09, Vol.1647, p.57-64

2016

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Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity

Acta neuropathologica communications, 2018-05, Vol.6 (1), p.42-14, Article 42

2018

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Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds

Toxicology and applied pharmacology, 2009-04, Vol.236 (2), p.142-153

2009

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Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice

The Journal of neuroscience, 2010-11, Vol.30 (46), p.15374-15382

2010

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Tau exhibits unique seeding properties in globular glial tauopathy

Acta neuropathologica communications, 2019-03, Vol.7 (1), p.36-36, Article 36

2019

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Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant

Acta neuropathologica communications, 2019-01, Vol.7 (1), p.10-10, Article 10

2019

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Efficient Neuronal Gene Transfer with AAV8 Leads to Neurotoxic Levels of Tau or Green Fluorescent Proteins

Molecular therapy, 2006-03, Vol.13 (3), p.517-527

2006

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Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia

Neuron (Cambridge, Mass.), 2023-03, Vol.111 (6), p.797-806.e6

2023

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Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model

Human molecular genetics, 2015-11, Vol.24 (21), p.6198-6212

2015

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Signal Peptide Peptidase Forms a Homodimer That Is Labeled by an Active Site-directed γ-Secretase Inhibitor

The Journal of biological chemistry, 2004-04, Vol.279 (15), p.15153-15160

2004

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Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brain

Journal of neuroscience methods, 2010-12, Vol.194 (1), p.144-153

2010

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Tau and neurofilament light‐chain as fluid biomarkers in spinocerebellar ataxia type 3

Kynurenine pathway dysfunction in the pathophysiology and treatment of depression: Evidences from animal and human studies

Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia

Astrocyte-derived clusterin suppresses amyloid formation in vivo

Progranulin regulates neuronal outgrowth independent of sortilin

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS

Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress

TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor

Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency

Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy

Clusterin ameliorates tau pathology in vivo by inhibiting fibril formation

Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36

Aß40 displays amyloidogenic properties in the non-transgenic mouse brain but does not exacerbate Aß42 toxicity in Drosophila

The extreme N-terminus of TDP-43 mediates the cytoplasmic aggregation of TDP-43 and associated toxicity in vivo

Loss of Tmem106b is unable to ameliorate frontotemporal dementia-like phenotypes in an AAV mouse model of C9ORF72-repeat induced toxicity

Paraoxonase 1 (PON1) modulates the toxicity of mixed organophosphorus compounds

Phosphorylation dynamics regulate Hsp27-mediated rescue of neuronal plasticity deficits in tau transgenic mice

Tau exhibits unique seeding properties in globular glial tauopathy

Enhanced phosphorylation of T153 in soluble tau is a defining biochemical feature of the A152T tau risk variant

Efficient Neuronal Gene Transfer with AAV8 Leads to Neurotoxic Levels of Tau or Green Fluorescent Proteins

C9ORF72 poly(GA) aggregates sequester and impair HR23 and nucleocytoplasmic transport proteins

Dorsomedial prefrontal hypoexcitability underlies lost empathy in frontotemporal dementia

Tau deposition drives neuropathological, inflammatory and behavioral abnormalities independently of neuronal loss in a novel mouse model

Signal Peptide Peptidase Forms a Homodimer That Is Labeled by an Active Site-directed γ-Secretase Inhibitor

Convection-enhanced delivery and systemic mannitol increase gene product distribution of AAV vectors 5, 8, and 9 and increase gene product in the adult mouse brain

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