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Revisiting the sigma-1 receptor as a biological target to treat affective and cognitive disorders

Neuroscience and biobehavioral reviews, 2022-01, Vol.132, p.1114-1136

2022

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Serotonin receptors in depression and anxiety: Insights from animal studies

Life sciences (1973), 2018-10, Vol.210, p.106-124

2018

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The selective 5-HT1A receptor biased agonists, F15599 and F13714, show antidepressant-like properties after a single administration in the mouse model of unpredictable chronic mild stress

Psychopharmacology, 2021-08, Vol.238 (8), p.2249-2260

2021

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Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines

Psychopharmacology, 2022-01, Vol.239 (1), p.229-242

2022

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The antidepressant-like activity of chiral xanthone derivatives may be mediated by 5-HT1A receptor and β-arrestin signalling

Journal of psychopharmacology (Oxford), 2020-12, Vol.34 (12), p.1431-1442

2020

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MK-801 and cognitive functions: Investigating the behavioral effects of a non-competitive NMDA receptor antagonist

Psychopharmacology, 2023-12, Vol.240 (12), p.2435-2457

2023

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Biased agonism in drug discovery: Is there a future for biased 5-HT1A receptor agonists in the treatment of neuropsychiatric diseases?

Pharmacology & therapeutics (Oxford), 2021-11, Vol.227, p.107872-107872, Article 107872

2021

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Beyond dopamine: Novel strategies for schizophrenia treatment

Medicinal research reviews, 2024-09, Vol.44 (5), p.2307-2330

2024

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Sex-dependent differences in animal cognition

Neuroscience and biobehavioral reviews, 2023-10, Vol.153, p.105374-105374, Article 105374

2023

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Biased agonism in drug discovery: Is there a future for biased 5-HT 1A receptor agonists in the treatment of neuropsychiatric diseases?

Pharmacology & therapeutics (Oxford), 2021-11, Vol.227, p.107872

2021

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Potential antidepressant and anxiolytic properties of new phenylpiperazine derivaties

Pharmacological reports, 2012-03, Vol.64 (2), p.503-503

2012

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Memory impairments in rodent depression models: A link with depression theories

Progress in neuro-psychopharmacology & biological psychiatry, 2023-07, Vol.125, p.110774-110774, Article 110774

2023

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The role of serotonergic, adrenergic and dopaminergic receptors in antidepressant-like effect

Pharmacological reports, 2016-04, Vol.68 (2), p.263-274

2016

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Single Administration of HBK-15—a Triple 5-HT1A, 5-HT7, and 5-HT3 Receptor Antagonist—Reverses Depressive-Like Behaviors in Mouse Model of Depression Induced by Corticosterone

Molecular neurobiology, 2018-05, Vol.55 (5), p.3931-3945

2018

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HBK-15, a Multimodal Compound, Showed an Anxiolytic-Like Effect in Rats

Neurochemical research, 2023-03, Vol.48 (3), p.839-845

2023

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Essential elements in depression and anxiety. Part I

Pharmacological reports, 2014-08, Vol.66 (4), p.534-544

2014

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The 5-HT1A receptor biased agonist, NLX-204, shows rapid-acting antidepressant-like properties and neurochemical changes in two mouse models of depression

Behavioural brain research, 2023-02, Vol.438, p.114207-114207, Article 114207

2023

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HBK‑10, A 5‑HT1A AND D2 RECEPTOR ANTAGONIST, SHOWS ANTIPSYCHOTIC‑LIKE ACTIVITY IN MICE

Acta neurobiologiae experimentalis, 2022-01, Vol.82, p.LXX

2022

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Mitogen‐activated protein kinase phosphatase‐2 deletion modifies ventral tegmental area function and connectivity and alters reward processing

The European journal of neuroscience, 2020-07, Vol.52 (2), p.2838-2852

2020

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Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system

Bioorganic & medicinal chemistry letters, 2019-11, Vol.29 (21), p.126679, Article 126679

2019

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The role of glutamatergic, GABA-ergic, and cholinergic receptors in depression and antidepressant-like effect

Pharmacological reports, 2016-04, Vol.68 (2), p.443-450

2016

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Discovery of Novel pERK1/2- or β‑Arrestin-Preferring 5‑HT1A Receptor-Biased Agonists: Diversified Therapeutic-like versus Side Effect Profile

Journal of medicinal chemistry, 2020-10, Vol.63 (19), p.10946-10971

2020

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Pitolisant protects mice chronically treated with corticosterone from some behavioral but not metabolic changes in corticosterone-induced depression model

Pharmacology, biochemistry and behavior, 2020-09, Vol.196, p.172974, Article 172974

2020

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Essential elements in depression and anxiety. Part II

Pharmacological reports, 2015-04, Vol.67 (2), p.187-194

2015

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Therapeutic potential of stilbenes in neuropsychiatric and neurological disorders: A comprehensive review of preclinical and clinical evidence

Phytotherapy research, 2024-03, Vol.38 (3), p.1400-1461

2024

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Revisiting the sigma-1 receptor as a biological target to treat affective and cognitive disorders

Serotonin receptors in depression and anxiety: Insights from animal studies

The selective 5-HT1A receptor biased agonists, F15599 and F13714, show antidepressant-like properties after a single administration in the mouse model of unpredictable chronic mild stress

Protease-activated receptor 2 activation induces behavioural changes associated with depression-like behaviour through microglial-independent modulation of inflammatory cytokines

The antidepressant-like activity of chiral xanthone derivatives may be mediated by 5-HT1A receptor and β-arrestin signalling

MK-801 and cognitive functions: Investigating the behavioral effects of a non-competitive NMDA receptor antagonist

Biased agonism in drug discovery: Is there a future for biased 5-HT1A receptor agonists in the treatment of neuropsychiatric diseases?

Beyond dopamine: Novel strategies for schizophrenia treatment

Sex-dependent differences in animal cognition

Biased agonism in drug discovery: Is there a future for biased 5-HT 1A receptor agonists in the treatment of neuropsychiatric diseases?

Potential antidepressant and anxiolytic properties of new phenylpiperazine derivaties

Memory impairments in rodent depression models: A link with depression theories

The role of serotonergic, adrenergic and dopaminergic receptors in antidepressant-like effect

Single Administration of HBK-15—a Triple 5-HT1A, 5-HT7, and 5-HT3 Receptor Antagonist—Reverses Depressive-Like Behaviors in Mouse Model of Depression Induced by Corticosterone

HBK-15, a Multimodal Compound, Showed an Anxiolytic-Like Effect in Rats

Essential elements in depression and anxiety. Part I

The 5-HT1A receptor biased agonist, NLX-204, shows rapid-acting antidepressant-like properties and neurochemical changes in two mouse models of depression

HBK‑10, A 5‑HT1A AND D2 RECEPTOR ANTAGONIST, SHOWS ANTIPSYCHOTIC‑LIKE ACTIVITY IN MICE

Mitogen‐activated protein kinase phosphatase‐2 deletion modifies ventral tegmental area function and connectivity and alters reward processing

Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system

The role of glutamatergic, GABA-ergic, and cholinergic receptors in depression and antidepressant-like effect

Discovery of Novel pERK1/2- or β‑Arrestin-Preferring 5‑HT1A Receptor-Biased Agonists: Diversified Therapeutic-like versus Side Effect Profile

Pitolisant protects mice chronically treated with corticosterone from some behavioral but not metabolic changes in corticosterone-induced depression model

Essential elements in depression and anxiety. Part II

Therapeutic potential of stilbenes in neuropsychiatric and neurological disorders: A comprehensive review of preclinical and clinical evidence

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