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Differential G protein activation by the long and short isoforms of the dopamine D2 receptor

British journal of pharmacology, 2024-05

2024

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Differential G protein activation by the long and short isoforms of the dopamine D 2 receptor

British journal of pharmacology, 2024-05

2024

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GproteinDb in 2024: new G protein-GPCR couplings, AlphaFold2-multimer models and interface interactions

Nucleic acids research, 2024-01, Vol.52 (D1), p.D466

2024

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Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5‑HT2A Receptor Agonists

ACS chemical neuroscience, 2023-08, Vol.14 (15), p.2727-2742

2023

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Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT 2A Receptor Agonists

ACS chemical neuroscience, 2023-08, Vol.14 (15), p.2727-2742

2023

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Structure–activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor

Basic & clinical pharmacology & toxicology, 2023-06, Vol.132 (6), p.459-471

2023

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Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2

Journal of medicinal chemistry, 2023-02, Vol.66 (4), p.3045-3057

2023

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GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources

Nucleic acids research, 2023-01, Vol.51 (D1), p.D395

2023

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Discovery of β‑Arrestin-Biased 25CN-NBOH-Derived 5‑HT2A Receptor Agonists

Journal of medicinal chemistry, 2022-09, Vol.65 (18), p.12031-12043

2022

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Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT 2A Receptor Agonists

Journal of medicinal chemistry, 2022-09, Vol.65 (18), p.12031-12043

2022

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Community guidelines for GPCR ligand bias: IUPHAR review 32

British journal of pharmacology, 2022-07, Vol.179 (14), p.3651-3674

2022

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Common coupling map advances GPCR-G protein selectivity

eLife, 2022-03, Vol.11

2022

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Ligand-directed bias of G protein signaling at the dopamine D 2 receptor

Cell chemical biology, 2022-02, Vol.29 (2), p.226

2022

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Ligand-directed bias of G protein signaling at the dopamine D2 receptor

Cell chemical biology, 2022-02, Vol.29 (2), p.226-238.e4

2022

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The G protein database, GproteinDb

Nucleic acids research, 2022-01, Vol.50 (D1), p.D518

2022

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A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro

Molecular brain, 2021-12, Vol.14 (1), p.173-173, Article 173

2021

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Molecular Determinants underlying Delta Selective Compound 2 (DS2) Activity at δ -Containing GABA A Receptors

Molecular pharmacology, 2021-07, Vol.100 (1), p.46-56

2021

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Targeting the APP-Mint2 Protein–Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid‑β Formation

Journal of the American Chemical Society, 2021-01, Vol.143 (2), p.891-901

2021

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GPCRdb in 2021: integrating GPCR sequence, structure and function

Nucleic acids research, 2021-01, Vol.49 (D1), p.D335

2021

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Delineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs

The Journal of biological chemistry, 2020-10, Vol.295 (40), p.13850-13861

2020

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Delineation of molecular determinants for FR900359 inhibition of G q/11 unlocks inhibition of Gα s

The Journal of biological chemistry, 2020-10, Vol.295 (40), p.13850

2020

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Pharmacology and function of the orphan GPR139 G protein‐coupled receptor

Basic & clinical pharmacology & toxicology, 2020-06, Vol.126 (S6), p.35-46

2020

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G protein‐coupled receptor pharmacology—The next generation

Basic & clinical pharmacology & toxicology, 2020-06, Vol.126 (S6), p.3-4

2020

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Differential G protein activation by the long and short isoforms of the dopamine D2 receptor

Differential G protein activation by the long and short isoforms of the dopamine D 2 receptor

GproteinDb in 2024: new G protein-GPCR couplings, AlphaFold2-multimer models and interface interactions

Structure–Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5‑HT2A Receptor Agonists

Structure-Activity Assessment and In-Depth Analysis of Biased Agonism in a Set of Phenylalkylamine 5-HT 2A Receptor Agonists

Structure–activity relationship of GPR15L peptide analogues and investigation of their interaction with the GPR15 receptor

Comprehensive Peptide Cyclization Examination Yields Optimized APP Scaffolds with Improved Affinity toward Mint2

GPCRdb in 2023: state-specific structure models using AlphaFold2 and new ligand resources

Discovery of β‑Arrestin-Biased 25CN-NBOH-Derived 5‑HT2A Receptor Agonists

Discovery of β-Arrestin-Biased 25CN-NBOH-Derived 5-HT 2A Receptor Agonists

Community guidelines for GPCR ligand bias: IUPHAR review 32

Effector membrane translocation biosensors reveal G protein and [beta]arrestin coupling profiles of 100 therapeutically relevant GPCRs

Common coupling map advances GPCR-G protein selectivity

Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

Ligand-directed bias of G protein signaling at the dopamine D 2 receptor

Ligand-directed bias of G protein signaling at the dopamine D2 receptor

The G protein database, GproteinDb

A novel red fluorescence dopamine biosensor selectively detects dopamine in the presence of norepinephrine in vitro

Molecular Determinants underlying Delta Selective Compound 2 (DS2) Activity at δ -Containing GABA A Receptors

Targeting the APP-Mint2 Protein–Protein Interaction with a Peptide-Based Inhibitor Reduces Amyloid‑β Formation

GPCRdb in 2021: integrating GPCR sequence, structure and function

Delineation of molecular determinants for FR900359 inhibition of Gq/11 unlocks inhibition of Gαs

Delineation of molecular determinants for FR900359 inhibition of G q/11 unlocks inhibition of Gα s

Pharmacology and function of the orphan GPR139 G protein‐coupled receptor

G protein‐coupled receptor pharmacology—The next generation

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