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Bioactivatable Pseudotripeptidization of Cyclic Dipeptides To Increase the Affinity toward Oligopeptide Transporter 1 for Enhanced Oral Absorption: An Application to Cyclo(l‑Hyp‑l‑Ser) (JBP485)

Journal of medicinal chemistry, 2019-09, Vol.62 (17), p.7708-7721

2019

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Pharmacokinetic drug–drug interactions of JBPOS0101 mediated by cytochrome P450 3A4 and UDP‐glucuronosyltransferases

Clinical and translational science, 2024-07, Vol.17 (7), p.e13892-n/a

2024

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Lineage-specific expansions of TET/JBP genes and a new class of DNA transposons shape fungal genomic and epigenetic landscapes

Proceedings of the National Academy of Sciences - PNAS, 2014-02, Vol.111 (5), p.1676-1683

2014

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Unusual Activity of a Chlamydomonas TET/JBP Family Enzyme

Biochemistry (Easton), 2019-09, Vol.58 (35), p.3627-3629

2019

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Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (48), p.E5149-E5158

2014

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Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads

Nature protocols, 2012-02, Vol.7 (2), p.340-350

2012

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The Methylosome, a 20S Complex Containing JBP1 and pICln, Produces Dimethylarginine-Modified Sm Proteins

Molecular and Cellular Biology, 2001-12, Vol.21 (24), p.8289-8300

2001

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Distant sequence regions of JBP1 contribute to J-DNA binding

Life science alliance, 2023-09, Vol.6 (9), p.e202302150

2023

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JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes

Nucleic acids research, 2009-04, Vol.37 (5), p.1452-1462

2009

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JBP1 and JBP2 Proteins Are Fe2+/2-Oxoglutarate-dependent Dioxygenases Regulating Hydroxylation of Thymidine Residues in Trypanosome DNA

The Journal of biological chemistry, 2012-06, Vol.287 (24), p.19886-19895

2012

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JBP485 promotes tear and mucin secretion in ocular surface epithelia

Scientific reports, 2015-05, Vol.5 (1), p.10248-10248, Article 10248

2015

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Clinical Significance of Truncated Mutant ΔJBP of TET2 Gene in Patients with Acute Myeloid Leukemia

Zhongguo shi yan xue ye xue za zhi, 2021-08, Vol.29 (4), p.1011

2021

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The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1

Nucleic acids research, 2011-07, Vol.39 (13), p.5715-5728

2011

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Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea

Proceedings of the National Academy of Sciences - PNAS, 2014-12, Vol.111 (48), p.16988-16988

2014

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New functions for DNA modifications by TET-JBP

Nature structural & molecular biology, 2012-11, Vol.19 (11), p.1061-1064

2012

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Gene expression of RNAP II, JBP1 and JBP2 in Leishmania major exposed to antimonials, amphotericin B and paromomycin

Annals of parasitology, 2018, Vol.64 (3), p.181-187

2018

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Protective effect of JBP485 on concanavalin A-induced liver injury in mice

Journal of pharmacy and pharmacology, 2009-06, Vol.61 (6), p.767-774

2009

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Simultaneous determination of three dipeptides (JBP485, Gly-Sar and JBP923) in the cell lysates by liquid chromatography-tandem mass spectrometry: application to identify the function of the PEPT1 transfected cell

Biomedical chromatography, 2014-12, Vol.28 (12), p.1839-1845

2014

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Peptide Cotransporter 1 in Intestine and Organic Anion Transporters in Kidney Are Targets of Interaction between JBP485 and Lisinopril in Rats

DRUG METABOLISM AND PHARMACOKINETICS, 2012, Vol.27 (2), p.232-241

2012

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Pharmacokinetics and Mechanism of Intestinal Absorption of JBP485 in Rats

DRUG METABOLISM AND PHARMACOKINETICS, 2010-01, Vol.25 (5), p.500-507

2010

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Inhibitory Effect of Zinc on the Absorption of JBP485 via the Gastrointestinal Oligopeptide Transporter (PEPT1) in Rats

DRUG METABOLISM AND PHARMACOKINETICS, 2011-01, Vol.26 (5), p.494-502

2011

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O-Glycoside Orientation Is an Essential Aspect of Base J Recognition by the Kinetoplastid DNA-Binding Protein JBP1

Angewandte Chemie International Edition, 2007-01, Vol.46 (16), p.2839-2843

2007

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Extensive host range determination and improved efficacy of the bacteriophage JBP901 in the presence of divalent cations for control of Bacillus cereus in Cheonggukjang

Food Science and Biotechnology, 2014, 23(2), , pp.499-504

2014

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An Application Framework Based on JBPM Workflow Engine

Applied Mechanics and Materials, 2014-05, Vol.556-562 (Mechatronics Engineering, Computing and Information Technology), p.5968-5971

2014

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Holographic Dark Energy Density and JBP Parametrization

International journal of theoretical physics, 2011-09, Vol.50 (9), p.2878-2883

2011

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1 – 25 von 13.346

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Bioactivatable Pseudotripeptidization of Cyclic Dipeptides To Increase the Affinity toward Oligopeptide Transporter 1 for Enhanced Oral Absorption: An Application to Cyclo(l‑Hyp‑l‑Ser) (JBP485)

Pharmacokinetic drug–drug interactions of JBPOS0101 mediated by cytochrome P450 3A4 and UDP‐glucuronosyltransferases

Lineage-specific expansions of TET/JBP genes and a new class of DNA transposons shape fungal genomic and epigenetic landscapes

Unusual Activity of a Chlamydomonas TET/JBP Family Enzyme

Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea

Pull-down of 5-hydroxymethylcytosine DNA using JBP1-coated magnetic beads

The Methylosome, a 20S Complex Containing JBP1 and pICln, Produces Dimethylarginine-Modified Sm Proteins

Distant sequence regions of JBP1 contribute to J-DNA binding

JBP1 and JBP2 are two distinct thymidine hydroxylases involved in J biosynthesis in genomic DNA of African trypanosomes

JBP1 and JBP2 Proteins Are Fe2+/2-Oxoglutarate-dependent Dioxygenases Regulating Hydroxylation of Thymidine Residues in Trypanosome DNA

JBP485 promotes tear and mucin secretion in ocular surface epithelia

Clinical Significance of Truncated Mutant ΔJBP of TET2 Gene in Patients with Acute Myeloid Leukemia

The structural basis for recognition of base J containing DNA by a novel DNA binding domain in JBP1

Simultaneous sequencing of oxidized methylcytosines produced by TET/JBP dioxygenases in Coprinopsis cinerea

New functions for DNA modifications by TET-JBP

Gene expression of RNAP II, JBP1 and JBP2 in Leishmania major exposed to antimonials, amphotericin B and paromomycin

Protective effect of JBP485 on concanavalin A-induced liver injury in mice

Simultaneous determination of three dipeptides (JBP485, Gly-Sar and JBP923) in the cell lysates by liquid chromatography-tandem mass spectrometry: application to identify the function of the PEPT1 transfected cell

Peptide Cotransporter 1 in Intestine and Organic Anion Transporters in Kidney Are Targets of Interaction between JBP485 and Lisinopril in Rats

Pharmacokinetics and Mechanism of Intestinal Absorption of JBP485 in Rats

Inhibitory Effect of Zinc on the Absorption of JBP485 via the Gastrointestinal Oligopeptide Transporter (PEPT1) in Rats

O-Glycoside Orientation Is an Essential Aspect of Base J Recognition by the Kinetoplastid DNA-Binding Protein JBP1

Extensive host range determination and improved efficacy of the bacteriophage JBP901 in the presence of divalent cations for control of Bacillus cereus in Cheonggukjang

An Application Framework Based on JBPM Workflow Engine

Holographic Dark Energy Density and JBP Parametrization

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