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Natural products for the treatment of type 2 diabetes mellitus: Pharmacology and mechanisms

Pharmacological research, 2018-04, Vol.130, p.451-465

2018

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MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2

Redox biology, 2018-05, Vol.15 (C), p.284-296

2018

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A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases

Frontiers in pharmacology, 2020-02, Vol.11, p.153-153

2020

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Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress

Redox biology, 2018-06, Vol.16, p.189-198

2018

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Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development

Pharmacological research, 2023-10, Vol.196, p.106925-106925, Article 106925

2023

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Dioscin alleviates alcoholic liver fibrosis by attenuating hepatic stellate cell activation via the TLR4/MyD88/NF-κB signaling pathway

Scientific reports, 2015-12, Vol.5 (1), p.18038-18038, Article 18038

2015

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MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1

Pharmacological research, 2019-08, Vol.146, p.104276, Article 104276

2019

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Potent effects of dioscin against obesity in mice

Scientific reports, 2015-01, Vol.5 (1), p.7973-7973, Article 7973

2015

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Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo

Toxicology letters, 2012-10, Vol.214 (1), p.69-80

2012

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Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation

Toxicology letters, 2018-03, Vol.284, p.37-45

2018

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Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation

Molecules (Basel, Switzerland), 2016-07, Vol.21 (7), p.952

2016

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Salvianolic acid B protects against acetaminophen hepatotoxicity by inducing Nrf2 and phase II detoxification gene expression via activation of the PI3K and PKC signaling pathways

Journal of pharmacological sciences, 2015-02, Vol.127 (2), p.203-210

2015

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Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2

Biomedicine & pharmacotherapy, 2024-05, Vol.174, p.116529-116529, Article 116529

2024

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Targeting P‐glycoprotein and SORCIN: Dihydromyricetin strengthens anti‐proliferative efficiency of adriamycin via MAPK/ERK and Ca2+‐mediated apoptosis pathways in MCF‐7/ADR and K562/ADR

Journal of cellular physiology, 2018-04, Vol.233 (4), p.3066-3079

2018

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Citrus nobiletin ameliorates experimental colitis by reducing inflammation and restoring impaired intestinal barrier function

Molecular nutrition & food research, 2015-05, Vol.59 (5), p.829-842

2015

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Potent effects of dioscin against liver fibrosis

Scientific reports, 2015-04, Vol.5 (1), p.9713-9713, Article 9713

2015

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Scutellarin exerts protective effects against atherosclerosis in rats by regulating the Hippo–FOXO3A and PI3K/AKT signaling pathways

Journal of cellular physiology, 2019-10, Vol.234 (10), p.18131-18145

2019

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Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis

Transplantation, 2014-09, Vol.98 (6), p.604

2014

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FABP4 contributes to renal interstitial fibrosis via mediating inflammation and lipid metabolism

Cell death & disease, 2019-05, Vol.10 (6), p.382-382

2019

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Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia–reperfusion injury through suppression of apoptosis and inflammation

Neurochemistry international, 2013-11, Vol.63 (5), p.522-532

2013

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Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease

Scientific reports, 2015-11, Vol.5 (1), p.16013-16013, Article 16013

2015

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EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways

Apoptosis (London), 2017-05, Vol.22 (5), p.672-680

2017

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Corrigendum to “Dioscin reduces ovariectomy-induced bone loss by enhancing osteoblastogenesis and inhibiting osteoclastogenesis” [Pharm. Res. 108 (2016) 90–101]

Pharmacological research, 2023-09, Vol.195, p.106894-106894, Article 106894

2023

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Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats

Food chemistry, 2013-12, Vol.141 (3), p.2108-2116

2013

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Neuroprotective Effect of Dioscin against Parkinson's Disease via Adjusting Dual-Specificity Phosphatase 6 (DUSP6)-Mediated Oxidative Stress

Molecules (Basel, Switzerland), 2022-05, Vol.27 (10), p.3151

2022

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Natural products for the treatment of type 2 diabetes mellitus: Pharmacology and mechanisms

MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2

A Review of the Anti-Inflammatory Effects of Rosmarinic Acid on Inflammatory Diseases

Protective effect of dioscin against doxorubicin-induced cardiotoxicity via adjusting microRNA-140-5p-mediated myocardial oxidative stress

Natural products in non-alcoholic fatty liver disease (NAFLD): Novel lead discovery for drug development

Dioscin alleviates alcoholic liver fibrosis by attenuating hepatic stellate cell activation via the TLR4/MyD88/NF-κB signaling pathway

MicroRNA-128-3p aggravates doxorubicin-induced liver injury by promoting oxidative stress via targeting Sirtuin-1

Potent effects of dioscin against obesity in mice

Dioscin, a natural steroid saponin, shows remarkable protective effect against acetaminophen-induced liver damage in vitro and in vivo

Protective effects of dioscin against fructose-induced renal damage via adjusting Sirt3-mediated oxidative stress, fibrosis, lipid metabolism and inflammation

Protective Effect of the Total Flavonoids from Rosa laevigata Michx Fruit on Renal Ischemia-Reperfusion Injury through Suppression of Oxidative Stress and Inflammation

Salvianolic acid B protects against acetaminophen hepatotoxicity by inducing Nrf2 and phase II detoxification gene expression via activation of the PI3K and PKC signaling pathways

Protective effect of esculentoside A against myocardial infarction via targeting C-X-C motif chemokine receptor 2

Targeting P‐glycoprotein and SORCIN: Dihydromyricetin strengthens anti‐proliferative efficiency of adriamycin via MAPK/ERK and Ca2+‐mediated apoptosis pathways in MCF‐7/ADR and K562/ADR

Citrus nobiletin ameliorates experimental colitis by reducing inflammation and restoring impaired intestinal barrier function

Potent effects of dioscin against liver fibrosis

Scutellarin exerts protective effects against atherosclerosis in rats by regulating the Hippo–FOXO3A and PI3K/AKT signaling pathways

Dioscin attenuates hepatic ischemia-reperfusion injury in rats through inhibition of oxidative-nitrative stress, inflammation and apoptosis

FABP4 contributes to renal interstitial fibrosis via mediating inflammation and lipid metabolism

Protective effect of flavonoid-rich extract from Rosa laevigata Michx on cerebral ischemia–reperfusion injury through suppression of apoptosis and inflammation

Inhibition of HMGB1 release via salvianolic acid B-mediated SIRT1 up-regulation protects rats against non-alcoholic fatty liver disease

EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways

Corrigendum to “Dioscin reduces ovariectomy-induced bone loss by enhancing osteoblastogenesis and inhibiting osteoclastogenesis” [Pharm. Res. 108 (2016) 90–101]

Effects of flavonoids from Rosa laevigata Michx fruit against high-fat diet-induced non-alcoholic fatty liver disease in rats

Neuroprotective Effect of Dioscin against Parkinson's Disease via Adjusting Dual-Specificity Phosphatase 6 (DUSP6)-Mediated Oxidative Stress

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