Details

Autor(en) / Beteiligte

• Fernandes, Alwyn R.
• Mortimer, David
• Wall, Richard J.
• Bell, David R.
• Rose, Martin
• Carr, Melanie
• Panton, Sean
• Smith, Frankie

Titel

Mixed halogenated dioxins/furans (PXDD/Fs) and biphenyls (PXBs) in food: Occurrence and toxic equivalent exposure using specific relative potencies

Ist Teil von

• Environment international, 2014-12, Vol.73, p.104-110

Ort / Verlag

Oxford: Elsevier Ltd

Erscheinungsjahr

2014

Link zum Volltext

Quelle

ScienceDirect Journals (5 years ago - present)

Beschreibungen/Notizen

• The occurrence of nineteen mixed halogenated (bromo-chloro) dibenzo-p-dioxins, dibenzofurans (PXDD/Fs) and biphenyls (PXBs) in a range of foods (n>100) was investigated. The analytical methodology used dual activated carbon column fractionation with high resolution mass spectrometric measurement (13,500–15,000 res). Occurrence was observed in most commonly consumed foods but the most frequent detections of these environmental contaminants were made in shellfish and offal. The concentrations of the individual compounds were condensed into toxic equivalents (TEQs) using recently reported relative potency values. Although representing only a small subset of the full range of toxic PXDD/Fs and PXBs, the TEQs estimated for these compounds ranged from 0.2% to approximately 15% (depending on the food matrix) of the corresponding TEQ for the fully chlorinated analogues. This finding is of great toxicological importance as it implies that a potentially greater magnitude of TEQ could be associated with the full range of toxic PXDD/Fs and PXBs, thus making a significant contribution to dioxin-like toxicity from the diet, to human exposure. •First occurrence data for PXDD/Fs and PXBs in commonly consumed foods•Evaluation of contribution to dioxin-like toxicity from PXDD/Fs and PXBs•Estimated human exposure to PXDD/Fs and PXBs through dietary intake