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Construction of sulfur-containing moieties in the total synthesis of natural products

Natural product reports, 2020-02, Vol.37 (2), p.246-275

2020

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Thiazole: A Review on Chemistry, Synthesis and Therapeutic Importance of its Derivatives

Current topics in medicinal chemistry, 2016-10, Vol.16 (26), p.2841

2016

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Cancer Selective Target Degradation by Folate-Caged PROTACs

Journal of the American Chemical Society, 2021-05, Vol.143 (19), p.7380-7387

2021

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Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery

European journal of medicinal chemistry, 2015-06, Vol.97, p.699-718

2015

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Synthesis, anticancer activity and mechanism of action of new thiazole derivatives

European journal of medicinal chemistry, 2018-01, Vol.144, p.874-886

2018

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Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors

International journal of biological macromolecules, 2020-11, Vol.163, p.1970-1988

2020

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Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

Journal of medicinal chemistry, 2017-11, Vol.60 (22), p.9184-9204

2017

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Synthesis, molecular modeling studies and evaluation of antifungal activity of a novel series of thiazole derivatives

European journal of medicinal chemistry, 2018-05, Vol.151, p.248-260

2018

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Regioselective Oxidative Trifluoromethylation of Imidazoheterocycles via C(sp2)–H Bond Functionalization

Journal of organic chemistry, 2015-02, Vol.80 (3), p.1332-1337

2015

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Novel 3‑Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism

Journal of medicinal chemistry, 2016-05, Vol.59 (10), p.4488-4510

2016

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Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii

European journal of medicinal chemistry, 2018-02, Vol.146, p.15-37

2018

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Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors

European journal of medicinal chemistry, 2019-11, Vol.182 (C), p.111648-111648, Article 111648

2019

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Synthesis, antimicrobial activity and advances in structure-activity relationships (SARs) of novel tri-substituted thiazole derivatives

European journal of medicinal chemistry, 2016-11, Vol.123, p.508-513

2016

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Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

Bioorganic chemistry, 2020-05, Vol.98, p.103761, Article 103761

2020

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Dialkoxybithiazole: A New Building Block for Head-to-Head Polymer Semiconductors

Journal of the American Chemical Society, 2013-02, Vol.135 (5), p.1986-1996

2013

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Substituted N‑Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery

Journal of medicinal chemistry, 2017-08, Vol.60 (16), p.7108-7122

2017

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Synthesis, antimicrobial and cytotoxic activities of some novel thiazole clubbed 1,3,4-oxadiazoles

European journal of medicinal chemistry, 2013-09, Vol.67, p.54-59

2013

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Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

Bioorganic & medicinal chemistry letters, 2013-07, Vol.23 (13), p.3741-3748

2013

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Recent Advances in Efficient and Selective Synthesis of Di-, Tri-, and Tetrasubstituted Alkenes via Pd-Catalyzed Alkenylation−Carbonyl Olefination Synergy

Accounts of chemical research, 2008-11, Vol.41 (11), p.1474-1485

2008

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Toward Ideality: The Synthesis of (+)-Kalkitoxin and (+)-Hydroxyphthioceranic Acid by Assembly-Line Synthesis

Journal of the American Chemical Society, 2015-04, Vol.137 (13), p.4398-4403

2015

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Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors

Journal of medicinal chemistry, 2015-04, Vol.58 (8), p.3548-3571

2015

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Discovery of Novel Histone Deacetylase 6 (HDAC6) Inhibitors with Enhanced Antitumor Immunity of Anti-PD-L1 Immunotherapy in Melanoma

Journal of medicinal chemistry, 2022-02, Vol.65 (3), p.2434-2457

2022

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2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation

European journal of medicinal chemistry, 2014-10, Vol.86, p.48-59

2014

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Synthesis and antiviral activity of new pyrazole and thiazole derivatives

European journal of medicinal chemistry, 2009-09, Vol.44 (9), p.3746-3753

2009

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Construction of sulfur-containing moieties in the total synthesis of natural products

Thiazole: A Review on Chemistry, Synthesis and Therapeutic Importance of its Derivatives

Cancer Selective Target Degradation by Folate-Caged PROTACs

Recent applications of 1,3-thiazole core structure in the identification of new lead compounds and drug discovery

Synthesis, anticancer activity and mechanism of action of new thiazole derivatives

Thiazolyl-pyrazoline derivatives: In vitro and in silico evaluation as potential acetylcholinesterase and carbonic anhydrase inhibitors

Discovery and Optimization of Potent, Cell-Active Pyrazole-Based Inhibitors of Lactate Dehydrogenase (LDH)

Synthesis, molecular modeling studies and evaluation of antifungal activity of a novel series of thiazole derivatives

Regioselective Oxidative Trifluoromethylation of Imidazoheterocycles via C(sp2)–H Bond Functionalization

Novel 3‑Aminothiazolquinolones: Design, Synthesis, Bioactive Evaluation, SARs, and Preliminary Antibacterial Mechanism

Discovery of 2-aminothiazolyl berberine derivatives as effectively antibacterial agents toward clinically drug-resistant Gram-negative Acinetobacter baumanii

Design, synthesis and biological evaluation of a new series of thiazolyl-pyrazolines as dual EGFR and HER2 inhibitors

Synthesis, antimicrobial activity and advances in structure-activity relationships (SARs) of novel tri-substituted thiazole derivatives

Discovery of thiazole-based-chalcones and 4-hetarylthiazoles as potent anticancer agents: Synthesis, docking study and anticancer activity

Dialkoxybithiazole: A New Building Block for Head-to-Head Polymer Semiconductors

Substituted N‑Phenyl-5-(2-(phenylamino)thiazol-4-yl)isoxazole-3-carboxamides Are Valuable Antitubercular Candidates that Evade Innate Efflux Machinery

Synthesis, antimicrobial and cytotoxic activities of some novel thiazole clubbed 1,3,4-oxadiazoles

Discovery of NVP-BYL719 a potent and selective phosphatidylinositol-3 kinase alpha inhibitor selected for clinical evaluation

Recent Advances in Efficient and Selective Synthesis of Di-, Tri-, and Tetrasubstituted Alkenes via Pd-Catalyzed Alkenylation−Carbonyl Olefination Synergy

Toward Ideality: The Synthesis of (+)-Kalkitoxin and (+)-Hydroxyphthioceranic Acid by Assembly-Line Synthesis

Discovery, Synthesis, and Biological Evaluation of Thiazoloquin(az)olin(on)es as Potent CD38 Inhibitors

Discovery of Novel Histone Deacetylase 6 (HDAC6) Inhibitors with Enhanced Antitumor Immunity of Anti-PD-L1 Immunotherapy in Melanoma

2-Pyridyl thiazoles as novel anti-Trypanosoma cruzi agents: Structural design, synthesis and pharmacological evaluation

Synthesis and antiviral activity of new pyrazole and thiazole derivatives

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