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Substance P and IL-33 administered together stimulate a marked secretion of IL-1β from human mast cells, inhibited by methoxyluteolin

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (40), p.E9381-E9390

2018

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Potential association of mast cells with coronavirus disease 2019

Annals of allergy, asthma, & immunology, 2021-03, Vol.126 (3), p.217-218

Theoharides, Theoharis C.

2021

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Substance P Promotes Wound Healing in Diabetes by Modulating Inflammation and Macrophage Phenotype

The American journal of pathology, 2015-06, Vol.185 (6), p.1638-1648

2015

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Neurokinin B Activates Arcuate Kisspeptin Neurons Through Multiple Tachykinin Receptors in the Male Mouse

Endocrinology (Philadelphia), 2013-08, Vol.154 (8), p.2750-2760

2013

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Naturally Occurring Missense MRGPRX2 Variants Display Loss of Function Phenotype for Mast Cell Degranulation in Response to Substance P, Hemokinin-1, Human β-Defensin-3, and Icatibant

The Journal of immunology (1950), 2018-07, Vol.201 (2), p.343-349

2018

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SP/NK1R system regulates carcinogenesis in prostate cancer: Shedding light on the antitumoral function of aprepitant

Biochimica et biophysica acta. Molecular cell research, 2022-05, Vol.1869 (5), p.119221-119221, Article 119221

2022

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Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (39), p.19635-19645

2019

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A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

The Journal of biological chemistry, 2021-01, Vol.296, p.100345-100345, Article 100345

2021

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Delivery of bone morphogenetic protein-2 and substance P using graphene oxide for bone regeneration

International journal of nanomedicine, 2014-01, Vol.9 Suppl 1 (1), p.107-116

2014

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Dynamin-related protein 1 differentially regulates FcεRI- and substance P-induced mast cell activation

Journal of allergy and clinical immunology, 2022-11, Vol.150 (5), p.1228-1231.e5

2022

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Correcting a widespread error: Neuroprotectant N-acetyl-L-tryptophan does not bind to the neurokinin-1 receptor

Molecular and cellular neuroscience, 2022-05, Vol.120, p.103728-103728, Article 103728

2022

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Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (22), p.e2220979120-e2220979120

2023

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Parvalbumin interneuron activity drives fast inhibition-induced vasoconstriction followed by slow substance P-mediated vasodilation

Proceedings of the National Academy of Sciences - PNAS, 2023-05, Vol.120 (18), p.e2220777120-e2220777120

2023

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Neurokinin B Stimulates GnRH Release in the Male Monkey (Macaca mulatta) and Is Colocalized with Kisspeptin in the Arcuate Nucleus

Endocrinology (Philadelphia), 2010-09, Vol.151 (9), p.4494-4503

2010

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The In Vitro Pro-inflammatory Functions of the SP/NK1R System in Prostate Cancer: a Focus on Nuclear Factor-Kappa B (NF-κB) and Its Pro-inflammatory Target Genes

Applied biochemistry and biotechnology, 2023-12, Vol.195 (12), p.7796-7807

2023

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The vasoactive effects of bradykinin, vasoactive intestinal peptide, calcitonin gene‐related peptide and neuropeptide Y depend on the perivascular tissue in porcine retinal arterioles in vitro

Acta ophthalmologica (Oxford, England), 2024-05, Vol.102 (3), p.349-356

2024

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Upregulated expression of substance P and NK1R in blood monocytes and B cells of patients with allergic rhinitis and asthma

Clinical and experimental immunology, 2022-10, Vol.210 (1), p.39-52

2022

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Substance P&dimethyloxallyl glycine‐loaded carboxymethyl chitosan/gelatin hydrogel for wound healing

Journal of biomedical materials research. Part A, 2023-03, Vol.111 (3), p.404-414

2023

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Alteration of colonic excitatory tachykininergic motility and enteric inflammation following dopaminergic nigrostriatal neurodegeneration

Journal of neuroinflammation, 2016-06, Vol.13 (1), p.146-146, Article 146

2016

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Regulation of Arcuate Neurons Coexpressing Kisspeptin, Neurokinin B, and Dynorphin by Modulators of Neurokinin 3 and κ-Opioid Receptors in Adult Male Mice

Endocrinology (Philadelphia), 2013-08, Vol.154 (8), p.2761-2771

2013

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Nacre-mimetic hydroxyapatite/chitosan/gelatin layered scaffolds modifying substance P for subchondral bone regeneration

Carbohydrate polymers, 2022-09, Vol.291, p.119575-119575, Article 119575

2022

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Substance P stimulates production of inflammatory cytokines in human disc cells

Spine (Philadelphia, Pa. 1976), 2013-10, Vol.38 (21), p.E1291-E1299

2013

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Substance P Regulates Puberty Onset and Fertility in the Female Mouse

Endocrinology (Philadelphia), 2015-06, Vol.156 (6), p.2313-2322

2015

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Kisspeptin Signaling Is Indispensable for Neurokinin B, but not Glutamate, Stimulation of Gonadotropin Secretion in Mice

Endocrinology (Philadelphia), 2012-01, Vol.153 (1), p.316-328

2012

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Rapid elucidation of agonist-driven regulation of the neurokinin 1 receptor using a GPCR phosphorylation immunoassay

European journal of pharmacology, 2024-06, Vol.973, p.176587-176587, Article 176587

2024

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Substance P and IL-33 administered together stimulate a marked secretion of IL-1β from human mast cells, inhibited by methoxyluteolin

Potential association of mast cells with coronavirus disease 2019

Substance P Promotes Wound Healing in Diabetes by Modulating Inflammation and Macrophage Phenotype

Neurokinin B Activates Arcuate Kisspeptin Neurons Through Multiple Tachykinin Receptors in the Male Mouse

Naturally Occurring Missense MRGPRX2 Variants Display Loss of Function Phenotype for Mast Cell Degranulation in Response to Substance P, Hemokinin-1, Human β-Defensin-3, and Icatibant

SP/NK1R system regulates carcinogenesis in prostate cancer: Shedding light on the antitumoral function of aprepitant

Neurokinin-1 receptor is an effective target for treating leukemia by inducing oxidative stress through mitochondrial calcium overload

A lipid-anchored neurokinin 1 receptor antagonist prolongs pain relief by a three-pronged mechanism of action targeting the receptor at the plasma membrane and in endosomes

Delivery of bone morphogenetic protein-2 and substance P using graphene oxide for bone regeneration

Dynamin-related protein 1 differentially regulates FcεRI- and substance P-induced mast cell activation

Correcting a widespread error: Neuroprotectant N-acetyl-L-tryptophan does not bind to the neurokinin-1 receptor

Therapeutic antagonism of the neurokinin 1 receptor in endosomes provides sustained pain relief

Parvalbumin interneuron activity drives fast inhibition-induced vasoconstriction followed by slow substance P-mediated vasodilation

Neurokinin B Stimulates GnRH Release in the Male Monkey (Macaca mulatta) and Is Colocalized with Kisspeptin in the Arcuate Nucleus

The In Vitro Pro-inflammatory Functions of the SP/NK1R System in Prostate Cancer: a Focus on Nuclear Factor-Kappa B (NF-κB) and Its Pro-inflammatory Target Genes

The vasoactive effects of bradykinin, vasoactive intestinal peptide, calcitonin gene‐related peptide and neuropeptide Y depend on the perivascular tissue in porcine retinal arterioles in vitro

Upregulated expression of substance P and NK1R in blood monocytes and B cells of patients with allergic rhinitis and asthma

Substance P&dimethyloxallyl glycine‐loaded carboxymethyl chitosan/gelatin hydrogel for wound healing

Alteration of colonic excitatory tachykininergic motility and enteric inflammation following dopaminergic nigrostriatal neurodegeneration

Regulation of Arcuate Neurons Coexpressing Kisspeptin, Neurokinin B, and Dynorphin by Modulators of Neurokinin 3 and κ-Opioid Receptors in Adult Male Mice

Nacre-mimetic hydroxyapatite/chitosan/gelatin layered scaffolds modifying substance P for subchondral bone regeneration

Substance P stimulates production of inflammatory cytokines in human disc cells

Substance P Regulates Puberty Onset and Fertility in the Female Mouse

Kisspeptin Signaling Is Indispensable for Neurokinin B, but not Glutamate, Stimulation of Gonadotropin Secretion in Mice

Rapid elucidation of agonist-driven regulation of the neurokinin 1 receptor using a GPCR phosphorylation immunoassay

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