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Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network

Development (Cambridge), 2017-07, Vol.144 (13), p.2428-2444

2017

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mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogenic KRas-mutant cancer cells

Oncogene, 2015-11, Vol.34 (45), p.5607-5616

2015

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Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor‐induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression

Molecular carcinogenesis, 2017-01, Vol.56 (1), p.18-35

2017

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Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells

Neuroscience letters, 2013-02, Vol.535, p.146-151

2013

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Functional interaction between Lypd6 and nicotinic acetylcholine receptors

Journal of neurochemistry, 2016-09, Vol.138 (6), p.806-820

2016

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The MAPK pathway across different malignancies: A new perspective

Cancer, 2014-11, Vol.120 (22), p.3446-3456

2014

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Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses

Journal of cell science, 2017-01, Vol.130 (1), p.203-218

2017

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p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

Cancer letters, 2014-03, Vol.344 (2), p.174-179

2014

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Efficacy of MEK inhibition in patients with histiocytic neoplasms

Nature (London), 2019-03, Vol.567 (7749), p.521-524

2019

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IL‐17‐induced cytokine release in human bronchial epithelial cells in vitro: role of mitogen‐activated protein (MAP) kinases

British journal of pharmacology, 2001-05, Vol.133 (1), p.200-206

2001

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Targeting Alterations in the RAF-MEK Pathway

Cancer discovery, 2019-03, Vol.9 (3), p.329-341

2019

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Roles of the Ras Raf MEK ERK pathway in leukemia therapy

Leukemia, 2011-07, Vol.25 (7), p.1080-1094

2011

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The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy

Journal of hematology and oncology, 2020-08, Vol.13 (1), p.113-19, Article 113

2020

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Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload

Cell death & disease, 2020-07, Vol.11 (7), p.574, Article 574

2020

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Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

Nature medicine, 2019-04, Vol.25 (4), p.620-627

2019

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Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

Oncogene, 2007-05, Vol.26 (22), p.3291-3310

2007

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Targeting RAS-ERK signalling in cancer: promises and challenges

Nature reviews. Drug discovery, 2014-12, Vol.13 (12), p.928-942

2014

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BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition

Cancer cell, 2015-09, Vol.28 (3), p.370-383

2015

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Resistance to TRK inhibition mediated by convergent MAPK pathway activation

Nature medicine, 2019-09, Vol.25 (9), p.1422-1427

2019

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MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models

Cell research, 2018-07, Vol.28 (7), p.719-729

2018

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Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

Nature communications, 2017-09, Vol.8 (1), p.606-18, Article 606

2017

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Negative feedback regulation of the ERK1/2 MAPK pathway

Cellular and Molecular Life Sciences, 2016-12, Vol.73 (23), p.4397-4413

2016

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Dynamic regulation of VEGF-inducible genes by an ERK/ERG/p300 transcriptional network

mTORC1 upregulation via ERK-dependent gene expression change confers intrinsic resistance to MEK inhibitors in oncogenic KRas-mutant cancer cells

Lebein, a snake venom disintegrin, suppresses human colon cancer cells proliferation and tumor‐induced angiogenesis through cell cycle arrest, apoptosis induction and inhibition of VEGF expression

Protective effects of caffeic acid and caffeic acid phenethyl ester against acrolein-induced neurotoxicity in HT22 mouse hippocampal cells

Functional interaction between Lypd6 and nicotinic acetylcholine receptors

The MAPK pathway across different malignancies: A new perspective

Comparison of cancer cells in 2D vs 3D culture reveals differences in AKT-mTOR-S6K signaling and drug responses

p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

The Hippo effector YAP promotes resistance to RAF- and MEK-targeted cancer therapies

Efficacy of MEK inhibition in patients with histiocytic neoplasms

IL‐17‐induced cytokine release in human bronchial epithelial cells in vitro: role of mitogen‐activated protein (MAP) kinases

Targeting Alterations in the RAF-MEK Pathway

Roles of the Ras Raf MEK ERK pathway in leukemia therapy

The MAPK and AMPK signalings: interplay and implication in targeted cancer therapy

Pyroptosis and ferroptosis induced by mixed lineage kinase 3 (MLK3) signaling in cardiomyocytes are essential for myocardial fibrosis in response to pressure overload

PAK signalling drives acquired drug resistance to MAPK inhibitors in BRAF-mutant melanomas

Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers

Targeting the Raf-MEK-ERK mitogen-activated protein kinase cascade for the treatment of cancer

Targeting RAS-ERK signalling in cancer: promises and challenges

Combination of ERK and autophagy inhibition as a treatment approach for pancreatic cancer

BRAF Mutants Evade ERK-Dependent Feedback by Different Mechanisms that Determine Their Sensitivity to Pharmacologic Inhibition

Resistance to TRK inhibition mediated by convergent MAPK pathway activation

MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models

Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer

Negative feedback regulation of the ERK1/2 MAPK pathway

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