Details

Autor(en) / Beteiligte

• Moriya, Yuki
• Kawano, Shin
• Okuda, Shujiro
• Watanabe, Yu
• Matsumoto, Masaki
• Takami, Tomoyo
• Kobayashi, Daiki
• Yamanouchi, Yoshinori
• Araki, Norie
• Yoshizawa, Akiyasu C
• Tabata, Tsuyoshi
• Iwasaki, Mio
• Sugiyama, Naoyuki
• Tanaka, Satoshi
• Goto, Susumu
• Ishihama, Yasushi

Titel

The jPOST environment: an integrated proteomics data repository and database

Ist Teil von

• Nucleic acids research, 2019-01, Vol.47 (D1), p.D1218-D1224

Ort / Verlag

England

Erscheinungsjahr

2019

Quelle

MEDLINE

Beschreibungen/Notizen

• Rapid progress is being made in mass spectrometry (MS)-based proteomics, yielding an increasing number of larger datasets with higher quality and higher throughput. To integrate proteomics datasets generated from various projects and institutions, we launched a project named jPOST (Japan ProteOme STandard Repository/Database, https://jpostdb.org/) in 2015. Its proteomics data repository, jPOSTrepo, began operations in 2016 and has accepted more than 10 TB of MS-based proteomics datasets in the past two years. In addition, we have developed a new proteomics database named jPOSTdb in which the published raw datasets in jPOSTrepo are reanalyzed using standardized protocol. jPOSTdb provides viewers showing the frequency of detected post-translational modifications, the co-occurrence of phosphorylation sites on a peptide and peptide sharing among proteoforms. jPOSTdb also provides basic statistical analysis tools to compare proteomics datasets.