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TIMP3 and TIMP1 are risk genes for bicuspid aortic valve and aortopathy in Turner syndrome

PLoS genetics, 2018-10, Vol.14 (10), p.e1007692-e1007692

2018

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Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion

Nucleic acids research, 2013-11, Vol.41 (21), p.9688-9704

2013

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Loss of TIMP3 by promoter methylation of Sp1 binding site promotes oral cancer metastasis

Cell death & disease, 2019-10, Vol.10 (11), p.793-17, Article 793

2019

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Loss of TIMP3, but not TIMP4, exacerbates thoracic and abdominal aortic aneurysm

Journal of molecular and cellular cardiology, 2023-11, Vol.184, p.61-74

2023

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Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

Proceedings of the National Academy of Sciences - PNAS, 2010-04, Vol.107 (16), p.7401-7406

2010

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TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors of Metalloproteinases

Cell reports (Cambridge), 2012-09, Vol.2 (3), p.568-579

2012

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Omeprazole prevents stress induced gastric ulcer by direct inhibition of MMP-2/TIMP-3 interactions

Free radical biology & medicine, 2022-03, Vol.181, p.221-234

2022

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TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1

Scientific reports, 2020-07, Vol.10 (1), p.12067-12067, Article 12067

2020

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Post-translational regulation and proteolytic activity of the metalloproteinase ADAMTS8

The Journal of biological chemistry, 2021-11, Vol.297 (5), p.101323-101323, Article 101323

2021

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Pregnancy-associated Inflammatory Myofibroblastic Tumors of the Uterus Are Clinically Distinct and Highly Enriched for TIMP3-ALK and THBS1-ALK Fusions

The American journal of surgical pathology, 2020-07, Vol.44 (7), p.970-981

2020

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Tendon stem/progenitor cells regulate inflammation in tendon healing via JNK and STAT3 signaling

The FASEB journal, 2017-09, Vol.31 (9), p.3991-3998

2017

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Hypertension Promotes the Proliferation and Migration of ccRCC Cells by Downregulation of TIMP3 in Tumor Endothelial Cells through the miR-21-5p/TGFBR2/P38/EGR1 Axis

Molecular cancer research, 2023-01, Vol.21 (1), p.62-75

2023

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Targeting miR-21 to treat psoriasis

Science translational medicine, 2014-02, Vol.6 (225), p.225re1

2014

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MiR-21 enhances melanoma invasiveness via inhibition of tissue inhibitor of metalloproteinases 3 expression: in vivo effects of MiR-21 inhibitor

PloS one, 2015-01, Vol.10 (1), p.e0115919-e0115919

2015

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Sex Distributions in Non-ABCA4 Autosomal Macular Dystrophies

Investigative ophthalmology & visual science, 2024-05, Vol.65 (5), p.9-9

2024

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Early-Onset TIMP3-Related Retinopathy Associated With Impaired Signal Peptide

JAMA ophthalmology, 2022-07, Vol.140 (7), p.730

2022

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Review: Mechanisms of TIMP-3 accumulation and pathogenesis in Sorsby fundus dystrophy

Molecular vision, 2024, Vol.30, p.74-91

2024

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IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages

Free radical biology & medicine, 2013-01, Vol.54, p.1-16

2013

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CircCSNK1G3 up‐regulates miR‐181b to promote growth and metastasis via TIMP3‐mediated epithelial to mesenchymal transitions in renal cell carcinoma

Journal of cellular and molecular medicine, 2022-03, Vol.26 (6), p.1729-1741

2022

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The Angiogenic Factor PlGF Mediates a Neuroimmune Interaction in the Spleen to Allow the Onset of Hypertension

Immunity (Cambridge, Mass.), 2014-11, Vol.41 (5), p.737-752

2014

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N 6 -methyladenosine ALKBH5 promotes non-small cell lung cancer progress by regulating TIMP3 stability

Gene, 2020-03, Vol.731, p.144348

2020

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Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis

European journal of pharmacology, 2015-03, Vol.750, p.141-150

2015

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The expression and localization of selected matrix metalloproteinases (MMP-2, -7 and -9) and their tissue inhibitors (TIMP-2 and -3) in follicular cysts of sows

Theriogenology, 2022-06, Vol.185, p.109-120

2022

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Elevated ratio of MMP2/MMP9 activity is associated with poor response to chemotherapy in osteosarcoma

BMC cancer, 2016-03, Vol.16 (222), p.223-223, Article 223

2016

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The Angiogenic Effect of microRNA-21 Targeting TIMP3 through the Regulation of MMP2 and MMP9

PloS one, 2016-02, Vol.11 (2), p.e0149537-e0149537

2016

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TIMP3 and TIMP1 are risk genes for bicuspid aortic valve and aortopathy in Turner syndrome

Both mature miR-17-5p and passenger strand miR-17-3p target TIMP3 and induce prostate tumor growth and invasion

Loss of TIMP3 by promoter methylation of Sp1 binding site promotes oral cancer metastasis

Loss of TIMP3, but not TIMP4, exacerbates thoracic and abdominal aortic aneurysm

Genetic variants near TIMP3 and high-density lipoprotein-associated loci influence susceptibility to age-related macular degeneration

TET1 Suppresses Cancer Invasion by Activating the Tissue Inhibitors of Metalloproteinases

Omeprazole prevents stress induced gastric ulcer by direct inhibition of MMP-2/TIMP-3 interactions

TIMP-3 facilitates binding of target metalloproteinases to the endocytic receptor LRP-1 and promotes scavenging of MMP-1

Post-translational regulation and proteolytic activity of the metalloproteinase ADAMTS8

Pregnancy-associated Inflammatory Myofibroblastic Tumors of the Uterus Are Clinically Distinct and Highly Enriched for TIMP3-ALK and THBS1-ALK Fusions

Tendon stem/progenitor cells regulate inflammation in tendon healing via JNK and STAT3 signaling

Hypertension Promotes the Proliferation and Migration of ccRCC Cells by Downregulation of TIMP3 in Tumor Endothelial Cells through the miR-21-5p/TGFBR2/P38/EGR1 Axis

Targeting miR-21 to treat psoriasis

MiR-21 enhances melanoma invasiveness via inhibition of tissue inhibitor of metalloproteinases 3 expression: in vivo effects of MiR-21 inhibitor

Sex Distributions in Non-ABCA4 Autosomal Macular Dystrophies

Early-Onset TIMP3-Related Retinopathy Associated With Impaired Signal Peptide

Review: Mechanisms of TIMP-3 accumulation and pathogenesis in Sorsby fundus dystrophy

IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages

CircCSNK1G3 up‐regulates miR‐181b to promote growth and metastasis via TIMP3‐mediated epithelial to mesenchymal transitions in renal cell carcinoma

The Angiogenic Factor PlGF Mediates a Neuroimmune Interaction in the Spleen to Allow the Onset of Hypertension

N 6 -methyladenosine ALKBH5 promotes non-small cell lung cancer progress by regulating TIMP3 stability

Evaluation of the anti-inflammatory, anti-catabolic and pro-anabolic effects of E-caryophyllene, myrcene and limonene in a cell model of osteoarthritis

The expression and localization of selected matrix metalloproteinases (MMP-2, -7 and -9) and their tissue inhibitors (TIMP-2 and -3) in follicular cysts of sows

Elevated ratio of MMP2/MMP9 activity is associated with poor response to chemotherapy in osteosarcoma

The Angiogenic Effect of microRNA-21 Targeting TIMP3 through the Regulation of MMP2 and MMP9

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