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Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance

Journal of the American Chemical Society, 2016-12, Vol.138 (49), p.16046-16055

2016

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Resolving Apparent Conflicts between Theoretical and Experimental Models of Phosphate Monoester Hydrolysis

Journal of the American Chemical Society, 2015-01, Vol.137 (3), p.1081-1093

2015

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Enzymatically Forming Intranuclear Peptide Assemblies for Selectively Killing Human Induced Pluripotent Stem Cells

Journal of the American Chemical Society, 2021-09, Vol.143 (38), p.15852-15862

2021

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Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins

Journal of the American Chemical Society, 2011-10, Vol.133 (42), p.16958-16969

2011

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Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers

Journal of the American Chemical Society, 2020-10, Vol.142 (40), p.17024-17038

2020

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Efficient Phosphodiester Cleaving Nanozymes Resulting from Multivalency and Local Medium Polarity Control

Journal of the American Chemical Society, 2014-01, Vol.136 (4), p.1158-1161

2014

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Enantioselective Synthesis of trans-Aryl- and -Heteroaryl-Substituted Cyclopropylboronates by Copper(I)-Catalyzed Reactions of Allylic Phosphates with a Diboron Derivative

Journal of the American Chemical Society, 2010-08, Vol.132 (33), p.11440-11442

2010

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Chiral Counteranion-Aided Asymmetric Hydrogenation of Acyclic Imines

Journal of the American Chemical Society, 2008-11, Vol.130 (44), p.14450-14451

2008

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Molecular Clip and Tweezer Introduce New Mechanisms of Enzyme Inhibition

Journal of the American Chemical Society, 2008-07, Vol.130 (30), p.9824-9828

2008

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N‑Heterocyclic Carbene–Copper-Catalyzed Group‑, Site‑, and Enantioselective Allylic Substitution with a Readily Accessible Propargyl(pinacolato)boron Reagent: Utility in Stereoselective Synthesis and Mechanistic Attributes

Journal of the American Chemical Society, 2015-07, Vol.137 (28), p.8948-8964

2015

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Highly Site- and Enantioselective Cu-Catalyzed Allylic Alkylation Reactions with Easily Accessible Vinylaluminum Reagents

Journal of the American Chemical Society, 2008-01, Vol.130 (2), p.446-447

2008

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Chemical Mechanism of the Phosphotriesterase from Sphingobium sp. Strain TCM1, an Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants

Journal of the American Chemical Society, 2016-03, Vol.138 (9), p.2921-2924

2016

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Enantioselective Synthesis of anti- and syn-Homopropargyl Alcohols via Chiral Brønsted Acid Catalyzed Asymmetric Allenylboration Reactions

Journal of the American Chemical Society, 2012-07, Vol.134 (26), p.10947-10952

2012

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DFT Computational Study of the Methanolytic Cleavage of DNA and RNA Phosphodiester Models Promoted by the Dinuclear Zn(II) Complex of 1,3-Bis(1,5,9-triazacyclododec-1-yl)propane

Journal of the American Chemical Society, 2013-11, Vol.135 (45), p.17209-17222

2013

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Copper-Catalyzed γ-Selective Allyl−Alkyl Coupling between Allylic Phosphates and Alkylboranes

Journal of the American Chemical Society, 2010-03, Vol.132 (9), p.2895-2897

2010

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Phosphate-Mediated Arginine Insertion into Lipid Membranes and Pore Formation by a Cationic Membrane Peptide from Solid-State NMR

Journal of the American Chemical Society, 2007-09, Vol.129 (37), p.11438-11446

2007

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On the Mechanism of Hydrolysis of Phosphate Monoesters Dianions in Solutions and Proteins

Journal of the American Chemical Society, 2006-11, Vol.128 (47), p.15310-15323

2006

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Phosphodiester Cleavage in Ribonuclease H Occurs via an Associative Two-Metal-Aided Catalytic Mechanism

Journal of the American Chemical Society, 2008-08, Vol.130 (33), p.10955-10962

2008

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Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation

Journal of the American Chemical Society, 2008-11, Vol.130 (47), p.16011-16020

2008

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Tripodal Tris-tacn and Tris-dpa Platforms for Assembling Phosphate-Templated Trimetallic Centers

Journal of the American Chemical Society, 2010-12, Vol.132 (49), p.17366-17369

2010

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Alkaline Phosphatase Mono- and Diesterase Reactions: Comparative Transition State Analysis

Journal of the American Chemical Society, 2006-02, Vol.128 (4), p.1293-1303

2006

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Allosteric Regulation of Phosphate Diester Transesterification Based upon a Dinuclear Zinc Catalyst Assembled via the Weak-Link Approach

Journal of the American Chemical Society, 2007-11, Vol.129 (46), p.14182-14183

2007

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Physical and Kinetic Analysis of the Cooperative Role of Metal Ions in Catalysis of Phosphodiester Cleavage by a Dinuclear Zn(II) Complex

Journal of the American Chemical Society, 2003-02, Vol.125 (7), p.1988-1993

2003

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Cleavage and Isomerization of UpU Promoted by Dinuclear Metal Ion Complexes

Journal of the American Chemical Society, 2008-04, Vol.130 (13), p.4232-4233

2008

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Dinuclear Zn(II) Complex Promotes Cleavage and Isomerization of 2-Hydroxypropyl Alkyl Phosphates by a Common Cyclic Phosphate Intermediate

Journal of the American Chemical Society, 2009-03, Vol.131 (11), p.4159-4166

2009

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Integrating Enzymatic Self-Assembly and Mitochondria Targeting for Selectively Killing Cancer Cells without Acquired Drug Resistance

Resolving Apparent Conflicts between Theoretical and Experimental Models of Phosphate Monoester Hydrolysis

Enzymatically Forming Intranuclear Peptide Assemblies for Selectively Killing Human Induced Pluripotent Stem Cells

Lysine-Specific Molecular Tweezers Are Broad-Spectrum Inhibitors of Assembly and Toxicity of Amyloid Proteins

Supramolecular Mechanism of Viral Envelope Disruption by Molecular Tweezers

Efficient Phosphodiester Cleaving Nanozymes Resulting from Multivalency and Local Medium Polarity Control

Enantioselective Synthesis of trans-Aryl- and -Heteroaryl-Substituted Cyclopropylboronates by Copper(I)-Catalyzed Reactions of Allylic Phosphates with a Diboron Derivative

Chiral Counteranion-Aided Asymmetric Hydrogenation of Acyclic Imines

Molecular Clip and Tweezer Introduce New Mechanisms of Enzyme Inhibition

N‑Heterocyclic Carbene–Copper-Catalyzed Group‑, Site‑, and Enantioselective Allylic Substitution with a Readily Accessible Propargyl(pinacolato)boron Reagent: Utility in Stereoselective Synthesis and Mechanistic Attributes

Highly Site- and Enantioselective Cu-Catalyzed Allylic Alkylation Reactions with Easily Accessible Vinylaluminum Reagents

Chemical Mechanism of the Phosphotriesterase from Sphingobium sp. Strain TCM1, an Enzyme Capable of Hydrolyzing Organophosphate Flame Retardants

Enantioselective Synthesis of anti- and syn-Homopropargyl Alcohols via Chiral Brønsted Acid Catalyzed Asymmetric Allenylboration Reactions

DFT Computational Study of the Methanolytic Cleavage of DNA and RNA Phosphodiester Models Promoted by the Dinuclear Zn(II) Complex of 1,3-Bis(1,5,9-triazacyclododec-1-yl)propane

Copper-Catalyzed γ-Selective Allyl−Alkyl Coupling between Allylic Phosphates and Alkylboranes

Phosphate-Mediated Arginine Insertion into Lipid Membranes and Pore Formation by a Cationic Membrane Peptide from Solid-State NMR

On the Mechanism of Hydrolysis of Phosphate Monoesters Dianions in Solutions and Proteins

Phosphodiester Cleavage in Ribonuclease H Occurs via an Associative Two-Metal-Aided Catalytic Mechanism

Aging of Cholinesterases Phosphylated by Tabun Proceeds through O-Dealkylation

Tripodal Tris-tacn and Tris-dpa Platforms for Assembling Phosphate-Templated Trimetallic Centers

Alkaline Phosphatase Mono- and Diesterase Reactions: Comparative Transition State Analysis

Allosteric Regulation of Phosphate Diester Transesterification Based upon a Dinuclear Zinc Catalyst Assembled via the Weak-Link Approach

Physical and Kinetic Analysis of the Cooperative Role of Metal Ions in Catalysis of Phosphodiester Cleavage by a Dinuclear Zn(II) Complex

Cleavage and Isomerization of UpU Promoted by Dinuclear Metal Ion Complexes

Dinuclear Zn(II) Complex Promotes Cleavage and Isomerization of 2-Hydroxypropyl Alkyl Phosphates by a Common Cyclic Phosphate Intermediate

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