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Nox (NADPH Oxidase) 1, Nox4, and Nox5 Promote Vascular Permeability and Neovascularization in Retinopathy

Hypertension (Dallas, Tex. 1979), 2020-04, Vol.75 (4), p.1091-1101

2020

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Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease

Diabetologia, 2017-05, Vol.60 (5), p.927-937

2017

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Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity

Redox biology, 2020-01, Vol.28, p.101330, Article 101330

2020

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Coordination between NADPH oxidase and vascular peroxidase 1 promotes dysfunctions of endothelial progenitor cells in hypoxia-induced pulmonary hypertensive rats

European journal of pharmacology, 2019-08, Vol.857, p.172459-172459, Article 172459

2019

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Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor

Biochemistry (Easton), 2014-08, Vol.53 (31), p.5111-5120

2014

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Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice

Nature communications, 2017-12, Vol.8 (1), p.1887-16, Article 1887

2017

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Genetic Targeting or Pharmacologic Inhibition of NADPH Oxidase Nox4 Provides Renoprotection in Long-Term Diabetic Nephropathy

Journal of the American Society of Nephrology, 2014-06, Vol.25 (6), p.1237-1254

2014

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Hypoxia-Dependent Regulation of Nonphagocytic NADPH Oxidase Subunit NOX4 in the Pulmonary Vasculature

Circulation research, 2007-08, Vol.101 (3), p.258-267

2007

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Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury

Journal of molecular and cellular cardiology, 2013-11, Vol.64, p.99-107

2013

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Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies

Annals of medicine (Helsinki), 2012-06, Vol.44 (S1), p.S2-S16

2012

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Hypoxia stabilizes the H 2 O 2 -producing oxidase Nox4 in cardiomyocytes via suppressing autophagy-related lysosomal degradation

Genes to cells : devoted to molecular & cellular mechanisms, 2024-01, Vol.29 (1), p.63-72

2024

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Regulation of Nox and Duox enzymatic activity and expression

Free radical biology & medicine, 2007-08, Vol.43 (3), p.319-331

2007

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Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes

American journal of physiology. Renal physiology, 2015-06, Vol.308 (11), p.F1276-F1287

2015

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Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis

Free radical biology & medicine, 2016-08, Vol.97, p.95-108

2016

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Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

Nature reviews. Drug discovery, 2011-06, Vol.10 (6), p.453-471

2011

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Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

Circulation research, 2012-04, Vol.110 (9), p.1217-1225

2012

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NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis

Arteriosclerosis, thrombosis, and vascular biology, 2021-02, Vol.41 (2), p.683

2021

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NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway

The Journal of biological chemistry, 2017-02, Vol.292 (7), p.3029-3038

2017

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Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes

Clinical science (1979), 2013-02, Vol.124 (3), p.191

2013

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Wound Healing After Alkali Burn Injury of the Cornea Involves Nox4-Type NADPH Oxidase

Investigative ophthalmology & visual science, 2020-10, Vol.61 (12), p.20-20

2020

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NADPH oxidase-4 promotes eccentric cardiac hypertrophy in response to volume overload

Cardiovascular research, 2021-01, Vol.117 (1), p.178-187

2021

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Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils

Journal of cellular biochemistry, 2013-03, Vol.114 (3), p.532-540

2013

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Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction

Biochimica et biophysica acta, 2014-06, Vol.1843 (6), p.1063-1075

2014

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Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress

European journal of pharmacology, 2019-09, Vol.859, p.172490, Article 172490

2019

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Molecular mechanisms of hypertension: role of Nox family NADPH oxidases

Current opinion in nephrology and hypertension, 2009-03, Vol.18 (2), p.122-127

2009

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Nox (NADPH Oxidase) 1, Nox4, and Nox5 Promote Vascular Permeability and Neovascularization in Retinopathy

Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease

Differential contribution of Nox1, Nox2 and Nox4 to kidney vascular oxidative stress and endothelial dysfunction in obesity

Coordination between NADPH oxidase and vascular peroxidase 1 promotes dysfunctions of endothelial progenitor cells in hypoxia-induced pulmonary hypertensive rats

Nox4: A Hydrogen Peroxide-Generating Oxygen Sensor

Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice

Genetic Targeting or Pharmacologic Inhibition of NADPH Oxidase Nox4 Provides Renoprotection in Long-Term Diabetic Nephropathy

Hypoxia-Dependent Regulation of Nonphagocytic NADPH Oxidase Subunit NOX4 in the Pulmonary Vasculature

Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury

Oxidative stress, Noxs, and hypertension: Experimental evidence and clinical controversies

Hypoxia stabilizes the H 2 O 2 -producing oxidase Nox4 in cardiomyocytes via suppressing autophagy-related lysosomal degradation

Regulation of Nox and Duox enzymatic activity and expression

Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes

Evaluation of NADPH oxidases as drug targets in a mouse model of familial amyotrophic lateral sclerosis

Combating oxidative stress in vascular disease: NADPH oxidases as therapeutic targets

Nox4 Is a Protective Reactive Oxygen Species Generating Vascular NADPH Oxidase

NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis

NADPH Oxidase 4 (Nox4) Suppresses Mitochondrial Biogenesis and Bioenergetics in Lung Fibroblasts via a Nuclear Factor Erythroid-derived 2-like 2 (Nrf2)-dependent Pathway

Renoprotective effects of a novel Nox1/4 inhibitor in a mouse model of Type 2 diabetes

Wound Healing After Alkali Burn Injury of the Cornea Involves Nox4-Type NADPH Oxidase

NADPH oxidase-4 promotes eccentric cardiac hypertrophy in response to volume overload

Reactive oxygen species-induced activation of ERK and p38 MAPK mediates PMA-induced NETs release from human neutrophils

Mechanism of endoplasmic reticulum stress-induced vascular endothelial dysfunction

Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress

Molecular mechanisms of hypertension: role of Nox family NADPH oxidases

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