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Reprogramming Substrate and Catalytic Promiscuity of Tryptophan Prenyltransferases

Journal of molecular biology, 2021-01, Vol.433 (2), p.166726, Article 166726

2021

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Structure-based protein engineering enables prenyl donor switching of a fungal aromatic prenyltransferase

Organic & biomolecular chemistry, 2018-10, Vol.16 (40), p.7461-7469

2018

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Novel approach to controlled protein crystallization through ligandation of yttrium cations

Journal of applied crystallography, 2011-08, Vol.44 (4), p.755-762

2011

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structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria

Proceedings of the National Academy of Sciences - PNAS, 2009-08, Vol.106 (34), p.14309-14314

2009

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A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis

Nature chemical biology, 2011-12, Vol.8 (2), p.154

2011

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The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation

Cellular and molecular life sciences : CMLS, 2011-09, Vol.68 (18), p.3121-3131

2011

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Exploring the Effect of Structure-Based Scaffold Hopping on the Inhibition of Coxsackievirus A24v Transduction by Pentavalent N-Acetylneuraminic Acid Conjugates

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8418

2021

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A sialic acid binding site in a human picornavirus

PLoS pathogens, 2014-10, Vol.10 (10), p.e1004401-e1004401

2014

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Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands

PLoS pathogens, 2010-01, Vol.6 (1), p.e1000723-e1000723

2010

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Structural Fine-Tuning of a Multifunctional Cytochrome P450 Monooxygenase

Journal of the American Chemical Society, 2011-02, Vol.133 (7), p.2292-2302

2011

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Structure of the extracellular portion of CD46 provides insights into its interactions with complement proteins and pathogens

PLoS pathogens, 2010-09, Vol.6 (9), p.e1001122-e1001122

2010

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Site-directed Mutagenesis Switching a Dimethylallyl Tryptophan Synthase to a Specific Tyrosine C3-Prenylating Enzyme

The Journal of biological chemistry, 2015-01, Vol.290 (3), p.1364-1373

2015

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Structural basis of head to head polyketide fusion by CorB

Chemical science (Cambridge), 2015-01, Vol.6 (11), p.6525-6536

2015

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Structure and Action of the N-oxygenase AurF from Streptomyces thioluteus

Journal of molecular biology, 2007-10, Vol.373 (1), p.65-74

2007

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Structure of the O-Acetylserine Sulfhydrylase Isoenzyme CysM from Escherichia coli

Biochemistry (Easton), 2005-06, Vol.44 (24), p.8620-8626

2005

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High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli

The FEBS journal, 2007-10, Vol.274 (20), p.5382-5389

2007

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A basidomycetous hydroxynaphthalene-prenylating enzyme exhibits promiscuity toward prenyl donors

Applied microbiology and biotechnology, 2023-08, Vol.107 (15), p.4845-4852

2023

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Complete Decoration of the Indolyl Residue in cyclo-l‑Trp‑l‑Trp with Geranyl Moieties by Using Engineered Dimethylallyl Transferases

Organic letters, 2018-11, Vol.20 (22), p.7201-7205

2018

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InVitro Reconstitution of a Cellular Phase-Transition Process that Involves the mRNA Decapping Machinery

Angewandte Chemie (International ed.), 2014-07, Vol.53 (28), p.7354-7359

International ed. in English, 2014

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Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes

The Journal of biological chemistry, 2013-01, Vol.288 (3), p.1991-2003

2013

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Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin

Journal of synchrotron radiation, 2012-05, Vol.19 (3), p.442-449

2012

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In Vitro Reconstitution of a Cellular Phase-Transition Process that Involves the mRNA Decapping Machinery

Angewandte Chemie (International ed.), 2014-07, Vol.53 (28), p.7354-7359

2014

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Structure-based protein engineering enables prenyl donor switching of a fungal aromatic prenyltransferaseElectronic supplementary information (ESI) available: Primers, NMR spectra with assignments, MS data, and determination of kinetic parameters (PDF). See DOI: 10.1039/c8ob02037j

2018-10

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Exploring divalent conjugates of 5- N -acetyl-neuraminic acid as inhibitors of coxsackievirus A24 variant (CVA24v) transduction

RSC advances, 2022-01, Vol.12 (4), p.2319-2331

2022

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Protein Crystallization in the Presence of a Metastable Liquid–Liquid Phase Separation

Crystal growth & design, 2020-12, Vol.20 (12), p.7951-7962

2020

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Reprogramming Substrate and Catalytic Promiscuity of Tryptophan Prenyltransferases

Structure-based protein engineering enables prenyl donor switching of a fungal aromatic prenyltransferase

Novel approach to controlled protein crystallization through ligandation of yttrium cations

structure of dimethylallyl tryptophan synthase reveals a common architecture of aromatic prenyltransferases in fungi and bacteria

A ketosynthase homolog uses malonyl units to form esters in cervimycin biosynthesis

The structure of the Klf4 DNA-binding domain links to self-renewal and macrophage differentiation

Exploring the Effect of Structure-Based Scaffold Hopping on the Inhibition of Coxsackievirus A24v Transduction by Pentavalent N-Acetylneuraminic Acid Conjugates

A sialic acid binding site in a human picornavirus

Structure of the HCMV UL16-MICB complex elucidates select binding of a viral immunoevasin to diverse NKG2D ligands

Structural Fine-Tuning of a Multifunctional Cytochrome P450 Monooxygenase

Structure of the extracellular portion of CD46 provides insights into its interactions with complement proteins and pathogens

Site-directed Mutagenesis Switching a Dimethylallyl Tryptophan Synthase to a Specific Tyrosine C3-Prenylating Enzyme

Structural basis of head to head polyketide fusion by CorB

Structure and Action of the N-oxygenase AurF from Streptomyces thioluteus

Structure of the O-Acetylserine Sulfhydrylase Isoenzyme CysM from Escherichia coli

High resolution structure and catalysis of O-acetylserine sulfhydrylase isozyme B from Escherichia coli

A basidomycetous hydroxynaphthalene-prenylating enzyme exhibits promiscuity toward prenyl donors

Complete Decoration of the Indolyl Residue in cyclo-l‑Trp‑l‑Trp with Geranyl Moieties by Using Engineered Dimethylallyl Transferases

InVitro Reconstitution of a Cellular Phase-Transition Process that Involves the mRNA Decapping Machinery

Structural Basis of the Interaction of MbtH-like Proteins, Putative Regulators of Nonribosomal Peptide Biosynthesis, with Adenylating Enzymes

Facilities for macromolecular crystallography at the Helmholtz-Zentrum Berlin

In Vitro Reconstitution of a Cellular Phase-Transition Process that Involves the mRNA Decapping Machinery

Structure-based protein engineering enables prenyl donor switching of a fungal aromatic prenyltransferaseElectronic supplementary information (ESI) available: Primers, NMR spectra with assignments, MS data, and determination of kinetic parameters (PDF). See DOI: 10.1039/c8ob02037j

Exploring divalent conjugates of 5- N -acetyl-neuraminic acid as inhibitors of coxsackievirus A24 variant (CVA24v) transduction

Protein Crystallization in the Presence of a Metastable Liquid–Liquid Phase Separation

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