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Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations

Arthritis & rheumatology (Hoboken, N.J.), 2016-06, Vol.68 (6), p.1442-1453

2016

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Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases

Frontiers in immunology, 2016-02, Vol.7, p.36-36

2016

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Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

Proceedings of the National Academy of Sciences - PNAS, 2010-09, Vol.107 (36), p.15838-15843

2010

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A dinucleotide deletion in CD24 confers protection against autoimmune diseases

PLoS genetics, 2007-04, Vol.3 (4), p.e49-e49

2007

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Complete Complement Components C4A and C4B Deficiencies in Human Kidney Diseases and Systemic Lupus Erythematosus

The Journal of immunology (1950), 2004-08, Vol.173 (4), p.2803-2814

2004

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Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus

Proceedings of the National Academy of Sciences - PNAS, 2007-03, Vol.104 (10), p.3961-3966

2007

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Genetic Sophistication of Human Complement Components C4A and C4B and RP-C4-CYP21-TNX (RCCX) Modules in the Major Histocompatibility Complex

American journal of human genetics, 2002-10, Vol.71 (4), p.823-837

2002

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Determining the One, Two, Three, or Four Long and Short Loci of Human Complement C4 in a Major Histocompatibility Complex Haplotype Encoding C4A or C4B Proteins

American journal of human genetics, 2002-10, Vol.71 (4), p.810-822

2002

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T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis

Clinical immunology (Orlando, Fla.), 2008-07, Vol.128 (1), p.1-7

2008

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Sensitive and Specific Real-Time Polymerase Chain Reaction Assays to Accurately Determine Copy Number Variations (CNVs) of Human Complement C4A, C4B, C4-Long, C4-Short, and RCCX Modules: Elucidation of C4 CNVs in 50 Consanguineous Subjects with Defined HLA Genotypes

Journal of Immunology, 2007-09, Vol.179 (5), p.3012-3025

2007

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Great genotypic and phenotypic diversities associated with copy-number variations of complement C4 and RP-C4-CYP21-TNX (RCCX) modules: A comparison of Asian-Indian and European American populations

Molecular immunology, 2009-04, Vol.46 (7), p.1289-1303

2009

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Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients

Pediatric diabetes, 2012-08, Vol.13 (5), p.408-418

2012

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Sex, MHC and complement C4 in autoimmune diseases

Trends in immunology, 2004-12, Vol.25 (12), p.694-699

2004

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Biomarker discovery in human SLE nephritis

Bulletin of the NYU Hospital for Joint Diseases, 2007-09, Vol.65 (3), p.187-193

2007

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Diversity in Intrinsic Strengths of the Human Complement System: Serum C4 Protein Concentrations Correlate with C4 Gene Size and Polygenic Variations, Hemolytic Activities, and Body Mass Index

The Journal of immunology (1950), 2003-09, Vol.171 (5), p.2734-2745

2003

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Deficiencies of human complement component C4A and C4B and heterozygosity in length variants of RP-C4-CYP21-TNX (RCCX) modules in caucasians. The load of RCCX genetic diversity on major histocompatibility complex-associated disease

The Journal of experimental medicine, 2000-06, Vol.191 (12), p.2183-2196

2000

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Frequency of Carriers of 8.1 Ancestral Haplotype and its Fragments in Two Caucasian Populations

Immunological investigations, 2007-01, Vol.36 (3), p.307-319

2007

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Genetic basis of tobacco smoking: strong association of a specific major histocompatibility complex haplotype on chromosome 6 with smoking behavior

International immunology, 2004-10, Vol.16 (10), p.1507-1514

2004

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Complement component C4 gene intron 9 as a phylogenetic marker for primates: long terminal repeats of the endogenous retrovirus ERV-K(C4) are a molecular clock of evolution

Immunogenetics (New York), 1995, Vol.42 (1), p.41-52

1995

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The intricate role of complement component C4 in human systemic lupus erythematosus

Current directions in autoimmunity, 2004, Vol.7, p.98-132

2004

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Of mice and men: the relevance of the mouse to the study of human SLE

Immunologic research, 2001-01, Vol.24 (2), p.211-224

2001

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The Molecular Basis of Complete Complement C4A and C4B Deficiencies in a Systemic Lupus Erythematosus Patient with Homozygous C4A and C4B Mutant Genes

The Journal of immunology (1950), 2002-08, Vol.169 (3), p.1570-1578

2002

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Association of a functional IRF7 variant with systemic lupus erythematosus

Arthritis and rheumatism, 2011-03, Vol.63 (3), p.749-754

2011

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Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations

Early Components of the Complement Classical Activation Pathway in Human Systemic Autoimmune Diseases

Sex-specific association of X-linked Toll-like receptor 7 (TLR7) with male systemic lupus erythematosus

Gene Copy-Number Variation and Associated Polymorphisms of Complement Component C4 in Human Systemic Lupus Erythematosus (SLE): Low Copy Number Is a Risk Factor for and High Copy Number Is a Protective Factor against SLE Susceptibility in European Americans

A dinucleotide deletion in CD24 confers protection against autoimmune diseases

Complete Complement Components C4A and C4B Deficiencies in Human Kidney Diseases and Systemic Lupus Erythematosus

Association of a common complement receptor 2 haplotype with increased risk of systemic lupus erythematosus

Genetic Sophistication of Human Complement Components C4A and C4B and RP-C4-CYP21-TNX (RCCX) Modules in the Major Histocompatibility Complex

The HLA 8.1 ancestral haplotype is strongly linked to the C allele of -429T>C promoter polymorphism of receptor of the advanced glycation endproduct (RAGE) gene. Haplotype-independent association of the -429C allele with high hemoglobinA1C levels in diabetic patients

Determining the One, Two, Three, or Four Long and Short Loci of Human Complement C4 in a Major Histocompatibility Complex Haplotype Encoding C4A or C4B Proteins

T cells and in situ cryoglobulin deposition in the pathogenesis of lupus nephritis

Sensitive and Specific Real-Time Polymerase Chain Reaction Assays to Accurately Determine Copy Number Variations (CNVs) of Human Complement C4A, C4B, C4-Long, C4-Short, and RCCX Modules: Elucidation of C4 CNVs in 50 Consanguineous Subjects with Defined HLA Genotypes

Great genotypic and phenotypic diversities associated with copy-number variations of complement C4 and RP-C4-CYP21-TNX (RCCX) modules: A comparison of Asian-Indian and European American populations

Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients

Sex, MHC and complement C4 in autoimmune diseases

Biomarker discovery in human SLE nephritis

Diversity in Intrinsic Strengths of the Human Complement System: Serum C4 Protein Concentrations Correlate with C4 Gene Size and Polygenic Variations, Hemolytic Activities, and Body Mass Index

Deficiencies of human complement component C4A and C4B and heterozygosity in length variants of RP-C4-CYP21-TNX (RCCX) modules in caucasians. The load of RCCX genetic diversity on major histocompatibility complex-associated disease

Frequency of Carriers of 8.1 Ancestral Haplotype and its Fragments in Two Caucasian Populations

Genetic basis of tobacco smoking: strong association of a specific major histocompatibility complex haplotype on chromosome 6 with smoking behavior

Complement component C4 gene intron 9 as a phylogenetic marker for primates: long terminal repeats of the endogenous retrovirus ERV-K(C4) are a molecular clock of evolution

The intricate role of complement component C4 in human systemic lupus erythematosus

Of mice and men: the relevance of the mouse to the study of human SLE

The Molecular Basis of Complete Complement C4A and C4B Deficiencies in a Systemic Lupus Erythematosus Patient with Homozygous C4A and C4B Mutant Genes

Association of a functional IRF7 variant with systemic lupus erythematosus

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