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Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome

The Journal of immunology (1950), 2015-09, Vol.195 (5), p.1939-1943

2015

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SLC19A1 transports immunoreactive cyclic dinucleotides

Nature (London), 2019-09, Vol.573 (7774), p.434-438

2019

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HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

Proceedings of the National Academy of Sciences - PNAS, 2015-02, Vol.112 (7), p.E747-E756

2015

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Antimalarial Drugs as Immune Modulators: New Mechanisms for Old Drugs

Annual review of medicine, 2017-01, Vol.68, p.317

2017

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A STING-based biosensor affords broad cyclic dinucleotide detection within single living eukaryotic cells

Nature communications, 2020-07, Vol.11 (1), p.3533-13, Article 3533

2020

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STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade

Science translational medicine, 2015-04, Vol.7 (283), p.283ra52

2015

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N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides

Infection and Immunity, 2011-02, Vol.79 (2), p.688-694

2011

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The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function

Cell, 2014-09, Vol.158 (6), p.1389-1401

2014

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Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant

PLoS genetics, 2018-08, Vol.14 (8), p.e1007574-e1007574

2018

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Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection

mBio, 2013-05, Vol.4 (3), p.e00282

2013

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High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival

PLoS genetics, 2018-04, Vol.14 (4), p.e1007301-e1007301

2018

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MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

Cell reports (Cambridge), 2023-08, Vol.42 (8), p.112805-112805, Article 112805

2023

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(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes

mBio, 2020-08, Vol.11 (4)

2020

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Nitric Oxide Synthase Stabilizes the Tetrahydrobiopterin Cofactor Radical by Controlling Its Protonation State

Journal of the American Chemical Society, 2010-08, Vol.132 (33), p.11812-11823

2010

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4-hydroxy-2-nonenal antimicrobial toxicity is neutralized by an intracellular pathogen

eLife, 2021-05, Vol.10

2021

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RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread

mBio, 2018-05, Vol.9 (3)

2018

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Flying Under the Radar: Immune Evasion by Group B Streptococcus

Cell host & microbe, 2016-07, Vol.20 (1), p.4-6

2016

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Cutting edge: Antimalarial drugs inhibit IFN-β production through blockade of cyclic GMP-AMP synthase-DNA interaction

The Journal of immunology (1950), 2015-05, Vol.194 (9), p.4089-4093

2015

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Development of a mariner-Based Transposon and Identification of Listeria monocytogenes Determinants, Including the Peptidyl-Prolyl Isomerase PrsA2, That Contribute to Its Hemolytic Phenotype

Journal of Bacteriology, 2009-06, Vol.191 (12), p.3950-3964

2009

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NO Formation by a Catalytically Self-Sufficient Bacterial Nitric Oxide Synthase from Sorangium Cellulosum

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (38), p.16221-16226

2009

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Cyclic dinucleotides at the forefront of innate immunity

Current opinion in cell biology, 2020-04, Vol.63, p.49-56

2020

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Too much of a good thing: regulated depletion of c-di-AMP in the bacterial cytoplasm

Current opinion in microbiology, 2016-04, Vol.30, p.22-29

2016

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Sustained Control of Pyruvate Carboxylase by the Essential Second Messenger Cyclic di-AMP in Bacillus subtilis

mBio, 2022-02, Vol.13 (1), p.e0360221-e0360221

2022

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c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

Science (American Association for the Advancement of Science), 2010-06, Vol.328 (5986), p.1703-1705

2010

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Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi-Goutières Syndrome

SLC19A1 transports immunoreactive cyclic dinucleotides

HD-domain phosphodiesterase mediates cooperative hydrolysis of c-di-AMP to affect bacterial growth and virulence

Antimalarial Drugs as Immune Modulators: New Mechanisms for Old Drugs

A STING-based biosensor affords broad cyclic dinucleotide detection within single living eukaryotic cells

STING agonist formulated cancer vaccines can cure established tumors resistant to PD-1 blockade

N-Ethyl-N-Nitrosourea-Induced Goldenticket Mouse Mutant Reveals an Essential Function of Sting in the In Vivo Interferon Response to Listeria monocytogenes and Cyclic Dinucleotides

The cyclic dinucleotide c-di-AMP is an allosteric regulator of metabolic enzyme function

Enhanced uptake of potassium or glycine betaine or export of cyclic-di-AMP restores osmoresistance in a high cyclic-di-AMP Lactococcus lactis mutant

Cyclic di-AMP is critical for Listeria monocytogenes growth, cell wall homeostasis, and establishment of infection

High-throughput interaction screens illuminate the role of c-di-AMP in cyanobacterial nighttime survival

MEF2A suppresses stress responses that trigger DDX41-dependent IFN production

(p)ppGpp and c-di-AMP Homeostasis Is Controlled by CbpB in Listeria monocytogenes

Endomembrane targeting of human OAS1 p46 augments antiviral activity

Nitric Oxide Synthase Stabilizes the Tetrahydrobiopterin Cofactor Radical by Controlling Its Protonation State

4-hydroxy-2-nonenal antimicrobial toxicity is neutralized by an intracellular pathogen

RECON-Dependent Inflammation in Hepatocytes Enhances Listeria monocytogenes Cell-to-Cell Spread

Flying Under the Radar: Immune Evasion by Group B Streptococcus

Cutting edge: Antimalarial drugs inhibit IFN-β production through blockade of cyclic GMP-AMP synthase-DNA interaction

Development of a mariner-Based Transposon and Identification of Listeria monocytogenes Determinants, Including the Peptidyl-Prolyl Isomerase PrsA2, That Contribute to Its Hemolytic Phenotype

NO Formation by a Catalytically Self-Sufficient Bacterial Nitric Oxide Synthase from Sorangium Cellulosum

Cyclic dinucleotides at the forefront of innate immunity

Too much of a good thing: regulated depletion of c-di-AMP in the bacterial cytoplasm

Sustained Control of Pyruvate Carboxylase by the Essential Second Messenger Cyclic di-AMP in Bacillus subtilis

c-di-AMP Secreted by Intracellular Listeria monocytogenes Activates a Host Type I Interferon Response

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