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Leveraging Human Plasma‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Cytochrome P450 3A4 by Modafinil

Clinical pharmacology and therapeutics, 2022-02, Vol.111 (2), p.425-434

2022

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Exploring the Use of Serum‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Hepatic Cytochromes P450 and Organic Anion Transporting Polypeptides

Clinical pharmacology and therapeutics, 2021-07, Vol.110 (1), p.248-258

2021

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Dose‐Dependent Inhibition of OATP1B by Rifampicin in Healthy Volunteers: Comprehensive Evaluation of Candidate Biomarkers and OATP1B Probe Drugs

Clinical pharmacology and therapeutics, 2020-04, Vol.107 (4), p.1004-1013

2020

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Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein‐Mediated Drug‐Drug Interactions in Healthy Volunteers

Clinical pharmacology and therapeutics, 2021-02, Vol.109 (2), p.507-516

2021

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Plasma extracellular nanovesicle (exosome)‐derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure

British journal of clinical pharmacology, 2019-01, Vol.85 (1), p.216-226

2019

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Identifying 2SLGBTQ+ individuals experiencing homelessness using Point-in-Time counts: Evidence from the 2021 Toronto Street Needs Assessment survey

PloS one, 2024, Vol.19 (4), p.e0298252-e0298252

2024

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Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries

European journal of clinical pharmacology, 2018-07, Vol.74 (7), p.913-920

2018

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Comprehensive Whole-Genome and Candidate Gene Analysis for Response to Statin Therapy in the Treating to New Targets (TNT) Cohort

Circulation. Cardiovascular genetics, 2009-04, Vol.2 (2), p.173

2009

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Evaluation of the Association of Polymorphisms With Palbociclib‐Induced Neutropenia: Pharmacogenetic Analysis of PALOMA‐2/‐3

The oncologist (Dayton, Ohio), 2021-07, Vol.26 (7), p.e1143-e1155

2021

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Meta‐Analysis of Noncompartmental Pharmacokinetic Parameters of Ertugliflozin to Evaluate Dose Proportionality and UGT1A9 Polymorphism Effect on Exposure

Journal of clinical pharmacology, 2021-09, Vol.61 (9), p.1220-1231

2021

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Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

American journal of physiology: endocrinology and metabolism, 2001-05, Vol.280 (5), p.E745-E751

2001

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Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity

European journal of clinical pharmacology, 2019-09, Vol.75 (9), p.1211-1218

2019

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The impact of a novel medication scanner on administration errors in the hospital setting: a before and after feasibility study

BMC medical informatics and decision making, 2022-03, Vol.22 (1), p.86-86, Article 86

2022

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Healthy Toronto by Design: Promoting a healthier built environment

Canadian journal of public health, 2015-01, Vol.106 (1), p.eS5-eS8

2015

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Functional confirmation that the R1488 variant in SCN9A results in complete loss-of-function of Nav1.7

BMC medical genetics, 2018-07, Vol.19 (1), p.124-124, Article 124

2018

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Significant Support for DAO as a Schizophrenia Susceptibility Locus: Examination of Five Genes Putatively Associated with Schizophrenia

Biological psychiatry (1969), 2007-05, Vol.61 (10), p.1195-1199

2007

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No Clinical Impact of CYP3A5 Gene Polymorphisms on the Pharmacokinetics and/or Efficacy of Maraviroc in Healthy Volunteers and HIV‐1–Infected Subjects

Journal of clinical pharmacology, 2019-01, Vol.59 (1), p.139-152

2019

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P190 - The effect of CYP2C9 and CYP2C19 genotype on the pharmacokinetics of PF 04965842, A JAK1 inhibitor in clinical development

Drug metabolism and pharmacokinetics, 2020, Vol.35 (1), p.S80-S80

2020

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A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype

Annals of the rheumatic diseases, 2012-06, Vol.71 (6), p.1042-1048

2012

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Functional confirmation that the R1488 variant in SCN9A results in complete loss-of-function of Na v 1.7

BMC medical genetics, 2018-07, Vol.19 (1), p.124

2018

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Outbreak of Human Adenovirus Type 3 Infection in a Pediatric Long-Term Care Facility—Illinois, 2005

Clinical infectious diseases, 2007-08, Vol.45 (4), p.416-420

2007

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Association between neprilysin polymorphisms and sporadic Alzheimer's disease

Neuroscience letters, 2007-11, Vol.427 (2), p.103-106

2007

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Constructing Remorse: Judges' Sentencing Decisions in Child Sexual Assault Cases

Journal of language and social psychology, 2007-12, Vol.26 (4), p.343-362

2007

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Frequency and function of CETP variants among individuals of Asian ancestry

Atherosclerosis, 2009-01, Vol.202 (1), p.241-247

2009

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Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes

The American heart journal, 2006-12, Vol.152 (6), p.1116-1122

2006

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Leveraging Human Plasma‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Cytochrome P450 3A4 by Modafinil

Exploring the Use of Serum‐Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Hepatic Cytochromes P450 and Organic Anion Transporting Polypeptides

Dose‐Dependent Inhibition of OATP1B by Rifampicin in Healthy Volunteers: Comprehensive Evaluation of Candidate Biomarkers and OATP1B Probe Drugs

Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein‐Mediated Drug‐Drug Interactions in Healthy Volunteers

Plasma extracellular nanovesicle (exosome)‐derived biomarkers for drug metabolism pathways: a novel approach to characterize variability in drug exposure

Identifying 2SLGBTQ+ individuals experiencing homelessness using Point-in-Time counts: Evidence from the 2021 Toronto Street Needs Assessment survey

Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries

Comprehensive Whole-Genome and Candidate Gene Analysis for Response to Statin Therapy in the Treating to New Targets (TNT) Cohort

Evaluation of the Association of Polymorphisms With Palbociclib‐Induced Neutropenia: Pharmacogenetic Analysis of PALOMA‐2/‐3

Meta‐Analysis of Noncompartmental Pharmacokinetic Parameters of Ertugliflozin to Evaluate Dose Proportionality and UGT1A9 Polymorphism Effect on Exposure

Adipose tissue tumor necrosis factor and interleukin-6 expression in human obesity and insulin resistance

Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity

The impact of a novel medication scanner on administration errors in the hospital setting: a before and after feasibility study

Healthy Toronto by Design: Promoting a healthier built environment

Functional confirmation that the R1488 variant in SCN9A results in complete loss-of-function of Nav1.7

Significant Support for DAO as a Schizophrenia Susceptibility Locus: Examination of Five Genes Putatively Associated with Schizophrenia

No Clinical Impact of CYP3A5 Gene Polymorphisms on the Pharmacokinetics and/or Efficacy of Maraviroc in Healthy Volunteers and HIV‐1–Infected Subjects

P190 - The effect of CYP2C9 and CYP2C19 genotype on the pharmacokinetics of PF 04965842, A JAK1 inhibitor in clinical development

A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype

Functional confirmation that the R1488 variant in SCN9A results in complete loss-of-function of Na v 1.7

Outbreak of Human Adenovirus Type 3 Infection in a Pediatric Long-Term Care Facility—Illinois, 2005

Association between neprilysin polymorphisms and sporadic Alzheimer's disease

Constructing Remorse: Judges' Sentencing Decisions in Child Sexual Assault Cases

Frequency and function of CETP variants among individuals of Asian ancestry

Association of torsades de pointes with novel and known single nucleotide polymorphisms in long QT syndrome genes

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