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Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Cell, 2012-08, Vol.150 (5), p.987-1001

2012

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Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations

Molecular cancer research, 2015-09, Vol.13 (9), p.1325-1335

2015

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KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS

Cell, 2018-02, Vol.172 (4), p.857-868.e15

2018

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Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios as Prognostic Factors after Stereotactic Radiation Therapy for Early-Stage Non–Small-Cell Lung Cancer

Journal of thoracic oncology, 2015-02, Vol.10 (2), p.280-285

2015

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In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C

Proceedings of the National Academy of Sciences - PNAS, 2014-06, Vol.111 (24), p.8895-8900

2014

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Case Report: Resolution of radiation pneumonitis with androgens and growth hormone

Frontiers in oncology, 2022-08, Vol.12

2022

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Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis

Cell, 2006-12, Vol.127 (5), p.941-954

2006

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Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor

Angewandte Chemie (International ed.), 2014-01, Vol.53 (1), p.199-204

International ed. in English, 2014

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Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution

Science (American Association for the Advancement of Science), 2009-05, Vol.324 (5931), p.1203-1206

2009

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Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C

Cell chemical biology, 2017-08, Vol.24 (8), p.1005-1016.e3

2017

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Shell feature: a new radiomics descriptor for predicting distant failure after radiotherapy in non-small cell lung cancer and cervix cancer

Physics in medicine & biology, 2018-05, Vol.63 (9), p.095007-095007

2018

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Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8), p.2574-2586

2013

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Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling

Cell reports (Cambridge), 2016-06, Vol.16 (1), p.28-36

2016

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GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing

The Journal of clinical investigation, 2023-11, Vol.133 (21)

2023

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Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT

Journal of experimental & clinical cancer research, 2021-07, Vol.40 (1), p.220-220, Article 220

2021

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Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability

International journal of molecular sciences, 2022-06, Vol.23 (13), p.7095

2022

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The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51

PLoS biology, 2021-06, Vol.19 (6), p.e3001281-e3001281

2021

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ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis

Nature communications, 2022-03, Vol.13 (1), p.1109-1109, Article 1109

2022

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Precision Hypofractionated Radiation Therapy in Poor Performing Patients With Non-Small Cell Lung Cancer: Phase 1 Dose Escalation Trial

International journal of radiation oncology, biology, physics, 2015-09, Vol.93 (1), p.72-81

2015

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Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms

Science (American Association for the Advancement of Science), 2004-02, Vol.303 (5660), p.983-988

2004

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Rapid assessment of DCLK1 inhibitors using a peptide substrate mobility shift assay

STAR protocols, 2021-06, Vol.2 (2), p.100587-100587, Article 100587

2021

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The to and fro of Rho

Structure (London), 2021-06, Vol.29 (6), p.507-509

Westover, Kenneth D

2021

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Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II

Science (American Association for the Advancement of Science), 2004-02, Vol.303 (5660), p.1014-1016

2004

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Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin

PloS one, 2016-05, Vol.11 (5), p.e0155217-e0155217

2016

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Quantitative Analysis of Hsp90-Client Interactions Reveals Principles of Substrate Recognition

Biochemical and Structural Analysis of Common Cancer-Associated KRAS Mutations

KRAS Dimerization Impacts MEK Inhibitor Sensitivity and Oncogenic Activity of Mutant KRAS

Neutrophil–Lymphocyte and Platelet–Lymphocyte Ratios as Prognostic Factors after Stereotactic Radiation Therapy for Early-Stage Non–Small-Cell Lung Cancer

A PHGDH inhibitor reveals coordination of serine synthesis and one-carbon unit fate

In situ selectivity profiling and crystal structure of SML-8-73-1, an active site inhibitor of oncogenic K-Ras G12C

Case Report: Resolution of radiation pneumonitis with androgens and growth hormone

Structural Basis of Transcription: Role of the Trigger Loop in Substrate Specificity and Catalysis

Therapeutic Targeting of Oncogenic K-Ras by a Covalent Catalytic Site Inhibitor

Structural Basis of Transcription: Backtracked RNA Polymerase II at 3.4 Angstrom Resolution

Potent and Selective Covalent Quinazoline Inhibitors of KRAS G12C

Shell feature: a new radiomics descriptor for predicting distant failure after radiotherapy in non-small cell lung cancer and cervix cancer

Characterization of Torin2, an ATP-Competitive Inhibitor of mTOR, ATM, and ATR

Direct Targeting of β-Catenin by a Small Molecule Stimulates Proteasomal Degradation and Suppresses Oncogenic Wnt/β-Catenin Signaling

GLUT3 promotes macrophage signaling and function via RAS-mediated endocytosis in atopic dermatitis and wound healing

Inhibiting the redox function of APE1 suppresses cervical cancer metastasis via disengagement of ZEB1 from E-cadherin in EMT

Thermal Shift Assay for Small GTPase Stability Screening: Evaluation and Suitability

The nonreceptor tyrosine kinase SRMS inhibits autophagy and promotes tumor growth by phosphorylating the scaffolding protein FKBP51

ADAP1 promotes latent HIV-1 reactivation by selectively tuning KRAS-ERK-AP-1 T cell signaling-transcriptional axis

Precision Hypofractionated Radiation Therapy in Poor Performing Patients With Non-Small Cell Lung Cancer: Phase 1 Dose Escalation Trial

Structural Basis of Transcription: An RNA Polymerase II-TFIIB Cocrystal at 4.5 Angstroms

Rapid assessment of DCLK1 inhibitors using a peptide substrate mobility shift assay

The to and fro of Rho

Structural Basis of Transcription: Separation of RNA from DNA by RNA Polymerase II

Inhibition of Cell Proliferation in an NRAS Mutant Melanoma Cell Line by Combining Sorafenib and α-Mangostin

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