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Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization

PLoS genetics, 2017-03, Vol.13 (3), p.e1006646-e1006646

2017

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A statistical framework for joint eQTL analysis in multiple tissues

PLoS genetics, 2013-05, Vol.9 (5), p.e1003486-e1003486

2013

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Robust Bayesian FDR Control Using Bayes Factors, with Applications to Multi-tissue eQTL Discovery

Statistics in biosciences, 2017-06, Vol.9 (1), p.28-49

Wen, Xiaoquan

2017

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Cross-population joint analysis of eQTLs: fine mapping and functional annotation

PLoS genetics, 2015-04, Vol.11 (4), p.e1005176-e1005176

2015

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Quantify and control reproducibility in high-throughput experiments

Nature methods, 2020-12, Vol.17 (12), p.1207-1213

2020

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Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation

Nature genetics, 2018-07, Vol.50 (7), p.956-967

2018

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Exploiting the GTEx resources to decipher the mechanisms at GWAS loci

Genome Biology, 2021-01, Vol.22 (1), p.49-49, Article 49

2021

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Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

Nature communications, 2017-05, Vol.8 (1), p.15382-15382, Article 15382

2017

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Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions

eLife, 2021-05, Vol.10

2021

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High-Resolution Mapping of Crossovers Reveals Extensive Variation in Fine-Scale Recombination Patterns Among Humans

Science (American Association for the Advancement of Science), 2008-03, Vol.319 (5868), p.1395-1398

2008

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PTWAS: investigating tissue-relevant causal molecular mechanisms of complex traits using probabilistic TWAS analysis

Genome Biology, 2020-09, Vol.21 (1), p.232-232, Article 232

2020

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A map of recent positive selection in the human genome

PLoS biology, 2006-03, Vol.4 (3), p.e72-e72

2006

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Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci

Nature communications, 2022-03, Vol.13 (1), p.1644-14, Article 1644

2022

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Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx

Genome Biology, 2020-09, Vol.21 (1), p.233-233, Article 233

2020

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Imperfect gold standard gene sets yield inaccurate evaluation of causal gene identification methods

Communications biology, 2024-07, Vol.7 (1), p.873-5, Article 873

2024

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USING LINEAR PREDICTORS TO IMPUTE ALLELE FREQUENCIES FROM SUMMARY OR POOLED GENOTYPE DATA

The annals of applied statistics, 2010-09, Vol.4 (3), p.1158-1182

2010

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Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis

PLoS genetics, 2020-12, Vol.16 (12), p.e1009060-e1009060

2020

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Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients

Nature communications, 2018-10, Vol.9 (1), p.4178-10, Article 4178

2018

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Psychosocial experiences modulate asthma-associated genes through gene-environment interactions

eLife, 2021-06, Vol.10

2021

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The genetic regulatory signature of type 2 diabetes in human skeletal muscle

Nature communications, 2016-06, Vol.7 (1), p.11764-12, Article 11764

2016

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A worldwide survey of haplotype variation and linkage disequilibrium in the human genome

Nature genetics, 2006-11, Vol.38 (11), p.1251-1260

2006

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Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs

Nature communications, 2023-04, Vol.14 (1), p.2229-16, Article 2229

2023

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Analysis of transcriptional changes in the immune system associated with pubertal development in a longitudinal cohort of children with asthma

Nature communications, 2023-01, Vol.14 (1), p.230-14, Article 230

2023

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MOLECULAR QTL DISCOVERY INCORPORATING GENOMIC ANNOTATIONS USING BAYESIAN FALSE DISCOVERY RATE CONTROL

The annals of applied statistics, 2016-09, Vol.10 (3), p.1619-1638

Wen, Xiaoquan

2016

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Environmental perturbations lead to extensive directional shifts in RNA processing

PLoS genetics, 2017-10, Vol.13 (10), p.e1006995-e1006995

2017

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Integrating molecular QTL data into genome-wide genetic association analysis: Probabilistic assessment of enrichment and colocalization

A statistical framework for joint eQTL analysis in multiple tissues

Robust Bayesian FDR Control Using Bayes Factors, with Applications to Multi-tissue eQTL Discovery

Cross-population joint analysis of eQTLs: fine mapping and functional annotation

Quantify and control reproducibility in high-throughput experiments

Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation

Exploiting the GTEx resources to decipher the mechanisms at GWAS loci

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

Functional dynamic genetic effects on gene regulation are specific to particular cell types and environmental conditions

High-Resolution Mapping of Crossovers Reveals Extensive Variation in Fine-Scale Recombination Patterns Among Humans

PTWAS: investigating tissue-relevant causal molecular mechanisms of complex traits using probabilistic TWAS analysis

A map of recent positive selection in the human genome

Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci

Impact of admixture and ancestry on eQTL analysis and GWAS colocalization in GTEx

Imperfect gold standard gene sets yield inaccurate evaluation of causal gene identification methods

USING LINEAR PREDICTORS TO IMPUTE ALLELE FREQUENCIES FROM SUMMARY OR POOLED GENOTYPE DATA

Integrating comprehensive functional annotations to boost power and accuracy in gene-based association analysis

Genetic signature to provide robust risk assessment of psoriatic arthritis development in psoriasis patients

Psychosocial experiences modulate asthma-associated genes through gene-environment interactions

The genetic regulatory signature of type 2 diabetes in human skeletal muscle

A worldwide survey of haplotype variation and linkage disequilibrium in the human genome

Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs

Analysis of transcriptional changes in the immune system associated with pubertal development in a longitudinal cohort of children with asthma

MOLECULAR QTL DISCOVERY INCORPORATING GENOMIC ANNOTATIONS USING BAYESIAN FALSE DISCOVERY RATE CONTROL

Environmental perturbations lead to extensive directional shifts in RNA processing

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