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Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2

The Journal of clinical investigation, 2019-03, Vol.129 (5), p.1845-1862

2019

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Circulating MicroRNAs as Novel Biomarkers for Platelet Activation

Circulation research, 2013-02, Vol.112 (4), p.595-600

2013

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Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic

The FASEB journal, 2004-05, Vol.18 (7), p.790-804

2004

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What can we learn from senescent platelets, their transcriptomes and proteomes?

Platelets (Edinburgh), 2023-12, Vol.34 (1), p.2200838-2200838

2023

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Newly Formed Reticulated Platelets Undermine Pharmacokinetically Short-Lived Antiplatelet Therapies

Arteriosclerosis, thrombosis, and vascular biology, 2017-05, Vol.37 (5), p.949

2017

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96-well plate-based aggregometry

Platelets (Edinburgh), 2018-10, Vol.29 (7), p.650-655

2018

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COX-2 selectivity alone does not define the cardiovascular risks associated with non-steroidal anti-inflammatory drugs

The Lancet (British edition), 2008-01, Vol.371 (9608), p.270-273

2008

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Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (43), p.17597-17602

2012

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COX-2 protects against atherosclerosis independently of local vascular prostacyclin: identification of COX-2 associated pathways implicate Rgl1 and lymphocyte networks

PloS one, 2014-06, Vol.9 (6), p.e98165

2014

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Cyclooxygenase-3 (COX-3): Filling in the Gaps toward a COX Continuum?

Proceedings of the National Academy of Sciences - PNAS, 2002-10, Vol.99 (21), p.13371-13373

2002

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Blockade of the purinergic P2Y₁₂ receptor greatly increases the platelet inhibitory actions of nitric oxide

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (39), p.15782-15787

2013

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Not all light transmission aggregation assays are created equal: qualitative differences between light transmission and 96-well plate aggregometry

Platelets (Edinburgh), 2018-10, Vol.29 (7), p.686-689

2018

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Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration

Arteriosclerosis, thrombosis, and vascular biology, 2007-12, Vol.27 (12), p.2606

2007

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LC-MS/MS confirms that COX-1 drives vascular prostacyclin whilst gene expression pattern reveals non-vascular sites of COX-2 expression

PloS one, 2013-07, Vol.8 (7), p.e69524-e69524

2013

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Nonsteroid Drug Selectivities for Cyclo-Oxygenase-1 Rather than Cyclo-Oxygenase-2 Are Associated with Human Gastrointestinal Toxicity: A Full in vitro Analysis

Proceedings of the National Academy of Sciences - PNAS, 1999-06, Vol.96 (13), p.7563-7568

1999

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Anti‐platelet therapy: cyclo‐oxygenase inhibition and the use of aspirin with particular regard to dual anti‐platelet therapy

British journal of clinical pharmacology, 2011-10, Vol.72 (4), p.619-633

2011

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Endogenous epoxygenases are modulators of monocyte/macrophage activity

PloS one, 2011-10, Vol.6 (10), p.e26591-e26591

2011

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Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia

Proceedings of the National Academy of Sciences - PNAS, 2013-09, Vol.110 (39), p.15812-15817

2013

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Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse

PloS one, 2011-05, Vol.6 (5), p.e20062

2011

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Expression and Activation of the Farnesoid X Receptor in the Vasculature

Proceedings of the National Academy of Sciences - PNAS, 2004-03, Vol.101 (10), p.3668-3673

2004

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Antiplatelet actions of statins and fibrates are mediated by PPARs

Arteriosclerosis, thrombosis, and vascular biology, 2009-05, Vol.29 (5), p.706

2009

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SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet procoagulant activity

Frontiers in cardiovascular medicine, 2023-01, Vol.9, p.1013262-1013262

2023

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Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms

Arteriosclerosis, thrombosis, and vascular biology, 2011-02, Vol.31 (2), p.384

2011

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Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage

Proceedings of the National Academy of Sciences - PNAS, 2019-08, Vol.116 (35), p.17444-17449

2019

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Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

British journal of pharmacology, 1999-11, Vol.128 (6), p.1121-1132

1999

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Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2

Circulating MicroRNAs as Novel Biomarkers for Platelet Activation

Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic

What can we learn from senescent platelets, their transcriptomes and proteomes?

Newly Formed Reticulated Platelets Undermine Pharmacokinetically Short-Lived Antiplatelet Therapies

96-well plate-based aggregometry

COX-2 selectivity alone does not define the cardiovascular risks associated with non-steroidal anti-inflammatory drugs

Cyclooxygenase-1, not cyclooxygenase-2, is responsible for physiological production of prostacyclin in the cardiovascular system

COX-2 protects against atherosclerosis independently of local vascular prostacyclin: identification of COX-2 associated pathways implicate Rgl1 and lymphocyte networks

Cyclooxygenase-3 (COX-3): Filling in the Gaps toward a COX Continuum?

Blockade of the purinergic P2Y₁₂ receptor greatly increases the platelet inhibitory actions of nitric oxide

Not all light transmission aggregation assays are created equal: qualitative differences between light transmission and 96-well plate aggregometry

Farnesoid x receptor ligands inhibit vascular smooth muscle cell inflammation and migration

LC-MS/MS confirms that COX-1 drives vascular prostacyclin whilst gene expression pattern reveals non-vascular sites of COX-2 expression

Nonsteroid Drug Selectivities for Cyclo-Oxygenase-1 Rather than Cyclo-Oxygenase-2 Are Associated with Human Gastrointestinal Toxicity: A Full in vitro Analysis

Anti‐platelet therapy: cyclo‐oxygenase inhibition and the use of aspirin with particular regard to dual anti‐platelet therapy

Endogenous epoxygenases are modulators of monocyte/macrophage activity

Hydrogen sulphide pathway contributes to the enhanced human platelet aggregation in hyperhomocysteinemia

Thrombosis is reduced by inhibition of COX-1, but unaffected by inhibition of COX-2, in an acute model of platelet activation in the mouse

Expression and Activation of the Farnesoid X Receptor in the Vasculature

Antiplatelet actions of statins and fibrates are mediated by PPARs

SARS-CoV-2 Spike protein activates TMEM16F-mediated platelet procoagulant activity

Role of shear stress in endothelial cell morphology and expression of cyclooxygenase isoforms

Histone H4 induces platelet ballooning and microparticle release during trauma hemorrhage

Cyclo‐oxygenase‐2: pharmacology, physiology, biochemistry and relevance to NSAID therapy

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