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Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

Immunity (Cambridge, Mass.), 2014-07, Vol.41 (1), p.14-20

2014

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The role of RAGE in host pathology and crosstalk between RAGE and TLR4 in innate immune signal transduction pathways

The FASEB journal, 2020-12, Vol.34 (12), p.15659-15674

2020

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CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

Proceedings of the National Academy of Sciences - PNAS, 2015-07, Vol.112 (27), p.8391-8396

2015

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The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Nature immunology, 2010-05, Vol.11 (5), p.395-402

2010

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Targeting TLR4 Signaling to Blunt Viral-Mediated Acute Lung Injury

Frontiers in immunology, 2021-07, Vol.12, p.705080-705080

2021

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The TLR4 antagonist Eritoran protects mice from lethal influenza infection

Nature (London), 2013-05, Vol.497 (7450), p.498-502

2013

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cAMP levels regulate macrophage alternative activation marker expression

Innate immunity (London, England), 2021-02, Vol.27 (2), p.133-142

2021

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TLR4/MyD88/PI3K interactions regulate TLR4 signaling

Journal of leukocyte biology, 2009-06, Vol.85 (6), p.966-977

2009

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Microbiota-Derived Metabolites, Indole-3-aldehyde and Indole-3-acetic Acid, Differentially Modulate Innate Cytokines and Stromal Remodeling Processes Associated with Autoimmune Arthritis

International journal of molecular sciences, 2021-02, Vol.22 (4), p.2017

2021

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5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential

The Journal of biological chemistry, 2012-11, Vol.287 (47), p.39776-39788

2012

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Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain

Proceedings of the National Academy of Sciences - PNAS, 2015-04, Vol.112 (17), p.5455-5460

2015

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Sustained Generation of Nitric Oxide and Control of Mycobacterial Infection Requires Argininosuccinate Synthase 1

Cell host & microbe, 2012-09, Vol.12 (3), p.313-323

2012

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Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3

Gastroenterology (New York, N.Y. 1943), 2008-07, Vol.135 (1), p.194-204.e3

2008

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Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2

Proceedings of the National Academy of Sciences - PNAS, 2009-09, Vol.106 (39), p.16799-16804

2009

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Space and time: New considerations about the relationship between Toll-like receptors (TLRs) and type I interferons (IFNs)

Cytokine (Philadelphia, Pa.), 2015-08, Vol.74 (2), p.171-174

2015

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C5a Activates a Pro-Inflammatory Gene Expression Profile in Human Gaucher iPSC-Derived Macrophages

International journal of molecular sciences, 2021-09, Vol.22 (18), p.9912

2021

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Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection

mBio, 2019-05, Vol.10 (3)

2019

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Salmonella Typhimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively

The Journal of immunology (1950), 2015-09, Vol.195 (5), p.2461-2471

2015

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Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists

The Journal of immunology (1950), 2012-07, Vol.189 (1), p.50-60

2012

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Protection against influenza-induced Acute Lung Injury (ALI) by enhanced induction of M2a macrophages: possible role of PPARγ/RXR ligands in IL-4-induced M2a macrophage differentiation

Frontiers in immunology, 2022-08, Vol.13, p.968336

2022

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A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza

Cell reports (Cambridge), 2015-06, Vol.11 (12), p.1941-1952

2015

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M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice

mBio, 2023-10, Vol.14 (5), p.e0120823-e0120823

2023

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Inhibition of TLR4 signaling by TRAM-derived decoy peptides in vitro and in vivo

The Journal of immunology (1950), 2013-03, Vol.190 (5), p.2263-2272

2013

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Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (44), p.18054-18059

2012

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Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections

mBio, 2018-03, Vol.9 (2)

2018

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Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

The role of RAGE in host pathology and crosstalk between RAGE and TLR4 in innate immune signal transduction pathways

CD14 dependence of TLR4 endocytosis and TRIF signaling displays ligand specificity and is dissociable in endotoxin tolerance

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

Targeting TLR4 Signaling to Blunt Viral-Mediated Acute Lung Injury

The TLR4 antagonist Eritoran protects mice from lethal influenza infection

cAMP levels regulate macrophage alternative activation marker expression

TLR4/MyD88/PI3K interactions regulate TLR4 signaling

Microbiota-Derived Metabolites, Indole-3-aldehyde and Indole-3-acetic Acid, Differentially Modulate Innate Cytokines and Stromal Remodeling Processes Associated with Autoimmune Arthritis

5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential

Inhibition of TLR2 signaling by small molecule inhibitors targeting a pocket within the TLR2 TIR domain

Sustained Generation of Nitric Oxide and Control of Mycobacterial Infection Requires Argininosuccinate Synthase 1

Gliadin Induces an Increase in Intestinal Permeability and Zonulin Release by Binding to the Chemokine Receptor CXCR3

Identification of human zonulin, a physiological modulator of tight junctions, as prehaptoglobin-2

Space and time: New considerations about the relationship between Toll-like receptors (TLRs) and type I interferons (IFNs)

C5a Activates a Pro-Inflammatory Gene Expression Profile in Human Gaucher iPSC-Derived Macrophages

Influenza "Trains" the Host for Enhanced Susceptibility to Secondary Bacterial Infection

Salmonella Typhimurium Co-Opts the Host Type I IFN System To Restrict Macrophage Innate Immune Transcriptional Responses Selectively

Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists

Protection against influenza-induced Acute Lung Injury (ALI) by enhanced induction of M2a macrophages: possible role of PPARγ/RXR ligands in IL-4-induced M2a macrophage differentiation

A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza

M2a macrophages facilitate resolution of chemically-induced colitis in TLR4-SNP mice

Inhibition of TLR4 signaling by TRAM-derived decoy peptides in vitro and in vivo

Induced pluripotent stem cell model recapitulates pathologic hallmarks of Gaucher disease

Serum High-Mobility-Group Box 1 as a Biomarker and a Therapeutic Target during Respiratory Virus Infections

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