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In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Molecular therapy, 2014-12, Vol.22 (12), p.2093-2106

2014

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Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease

Neurobiology of disease, 2015-04, Vol.76, p.46-56

2015

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Moderate increase in temperature may exacerbate neuroinflammatory processes in the brain: Human cell culture studies

Journal of neuroimmunology, 2011-04, Vol.233 (1), p.65-72

2011

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Secreted phospholipase A2 group IIA is a neurotoxin released by stimulated human glial cells

Molecular and cellular neuroscience, 2012-04, Vol.49 (4), p.430-438

2012

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Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

Nucleic acids research, 2013-11, Vol.41 (21), p.9634

2013

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An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes

Human molecular genetics, 2016-09, Vol.25 (17), p.3654-3675

2016

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Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression

Scientific reports, 2015-07, Vol.5 (1), p.12166-12166, Article 12166

2015

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Mitochondrial transcription factor A (Tfam) is a pro-inflammatory extracellular signaling molecule recognized by brain microglia

Molecular and cellular neuroscience, 2014-05, Vol.60, p.88-96

2014

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Neuronal TNFα, Not α‐Syn, Underlies PDD‐Like Disease Progression in IFNβ‐KO Mice

Annals of neurology, 2021-11, Vol.90 (5), p.789-807

2021

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A fully humanized transgenic mouse model of Huntington disease

Human molecular genetics, 2013-01, Vol.22 (1), p.18-34

2013

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HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo

Human molecular genetics, 2018-01, Vol.27 (2), p.239-253

2018

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Synthesis and biological evaluation of novel pyrazolyl-2,4-thiazolidinediones as anti-inflammatory and neuroprotective agents

Bioorganic & medicinal chemistry, 2010-03, Vol.18 (5), p.2019-2028

2010

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Secreted phospholipase A(2) group IIA is a neurotoxin released by stimulated human glial cells

Molecular and cellular neuroscience, 2012-04, Vol.49 (4), p.430-438

2012

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A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles

Human molecular genetics, 2017-03, Vol.26 (6), p.1115-1132

2017

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Synthesis and biological evaluation of novel pyrazole compounds

Bioorganic & medicinal chemistry, 2010-08, Vol.18 (15), p.5685-5696

2010

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Cultured adult porcine astrocytes and microglia express functional interferon-γ receptors and exhibit toxicity towards SH-SY5Y cells

Brain research bulletin, 2011-02, Vol.84 (3), p.244-251

2011

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696. Pre-Clinical Evaluation of Allele-Specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Molecular therapy, 2015-05, Vol.23, p.S277-S277

2015

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Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer

The New England journal of medicine, 2022-07, Vol.387 (1), p.9-20

2022

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Multidimensional tropical forest recovery

Science (American Association for the Advancement of Science), 2021-12, Vol.374 (6573), p.1370-1376

2021

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Parent Volatiles in Comet 9P/Tempel 1: Before and After Impact

Science (American Association for the Advancement of Science), 2005-10, Vol.310 (5746), p.270-274

2005

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The Peculiar Volatile Composition of Comet 8P/Tuttle: A Contact Binary of Chemically Distinct Cometesimals?

The Astrophysical journal, 2008-06, Vol.680 (1), p.L61-L64

2008

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Trasplante cardíaco y autólogo de células progenitoras hematopoyéticas en pacientes con amiloidosis AL

Archivos de cardiología de México, 2023-10, Vol.93 (4)

2023

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Nitric oxide production by Peromyscus yucatanicus (Rodentia) infected with Leishmania (Leishmania) mexicana

Memórias do Instituto Oswaldo Cruz, 2013-04, Vol.108 (2), p.172-177

2013

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Increased expression of Mcl-1 is responsible for the blockage of TRAIL-induced apoptosis mediated by EGF/ErbB1 signaling pathway

Journal of cellular biochemistry, 2003-08, Vol.89 (6), p.1177-1192

2003

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In Vivo Evaluation of Candidate Allele-specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease

Moderate increase in temperature may exacerbate neuroinflammatory processes in the brain: Human cell culture studies

Secreted phospholipase A2 group IIA is a neurotoxin released by stimulated human glial cells

Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS

An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes

Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression

Mitochondrial transcription factor A (Tfam) is a pro-inflammatory extracellular signaling molecule recognized by brain microglia

Neuronal TNFα, Not α‐Syn, Underlies PDD‐Like Disease Progression in IFNβ‐KO Mice

A fully humanized transgenic mouse model of Huntington disease

HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo

Synthesis and biological evaluation of novel pyrazolyl-2,4-thiazolidinediones as anti-inflammatory and neuroprotective agents

Secreted phospholipase A(2) group IIA is a neurotoxin released by stimulated human glial cells

A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles

Synthesis and biological evaluation of novel pyrazole compounds

Cultured adult porcine astrocytes and microglia express functional interferon-γ receptors and exhibit toxicity towards SH-SY5Y cells

696. Pre-Clinical Evaluation of Allele-Specific Mutant Huntingtin Gene Silencing Antisense Oligonucleotides

Trastuzumab Deruxtecan in Previously Treated HER2-Low Advanced Breast Cancer

Multidimensional tropical forest recovery

Parent Volatiles in Comet 9P/Tempel 1: Before and After Impact

Impaired muscle strength is associated with ultrastructure damage in myositis

The Peculiar Volatile Composition of Comet 8P/Tuttle: A Contact Binary of Chemically Distinct Cometesimals?

Trasplante cardíaco y autólogo de células progenitoras hematopoyéticas en pacientes con amiloidosis AL

Nitric oxide production by Peromyscus yucatanicus (Rodentia) infected with Leishmania (Leishmania) mexicana

Increased expression of Mcl-1 is responsible for the blockage of TRAIL-induced apoptosis mediated by EGF/ErbB1 signaling pathway

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