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Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging

American journal of physiology. Heart and circulatory physiology, 2017-01, Vol.312 (1), p.H1-H20

2017

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Mechanisms of Vascular Aging

Circulation research, 2018-09, Vol.123 (7), p.849-867

2018

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Hypertension-induced cognitive impairment: from pathophysiology to public health

Nature reviews. Nephrology, 2021-10, Vol.17 (10), p.639-654

2021

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Role of mitochondrial oxidative stress in hypertension

American journal of physiology. Heart and circulatory physiology, 2013-11, Vol.305 (10), p.H1417-H1427

2013

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Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults

PloS one, 2021-05, Vol.16 (5), p.e0250043-e0250043

2021

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Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline

Experimental gerontology, 2017-08, Vol.94, p.52-58

2017

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Mitochondria and Cardiovascular Aging

Circulation research, 2012-04, Vol.110 (8), p.1109-1124

2012

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Role of Vitamin D Deficiency in the Pathogenesis of Cardiovascular and Cerebrovascular Diseases

Nutrients, 2023-01, Vol.15 (2), p.334

2023

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Role of endothelial NAD + deficiency in age-related vascular dysfunction

American journal of physiology. Heart and circulatory physiology, 2019-06, Vol.316 (6), p.H1253-H1266

2019

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Cerebral microhemorrhages: mechanisms, consequences, and prevention

American journal of physiology. Heart and circulatory physiology, 2017-06, Vol.312 (6), p.H1128-H1143

2017

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Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability

The journals of gerontology. Series A, Biological sciences and medical sciences, 2019-08, Vol.74 (9), p.1417-1421

2019

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Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

Redox biology, 2019-06, Vol.24, p.101192-101192, Article 101192

2019

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Endothelial Dysfunction and Impaired Neurovascular Coupling Responses Precede Cognitive Impairment in a Mouse Model of Geriatric Sepsis

Frontiers in aging neuroscience, 2021-05, Vol.13, p.644733-644733

2021

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Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses

Scientific reports, 2021-10, Vol.11 (1), p.20994-20994, Article 20994

2021

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Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

American journal of physiology. Heart and circulatory physiology, 2010-07, Vol.299 (1), p.H18-H24

2010

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Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells

American journal of physiology. Heart and circulatory physiology, 2009-11, Vol.297 (5), p.H1876-H1881

2009

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Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study

PloS one, 2023-08, Vol.18 (8), p.e0289508-e0289508

2023

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Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype

The journals of gerontology. Series A, Biological sciences and medical sciences, 2018-06, Vol.73 (7), p.853-863

2018

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The Role of Methionine-Rich Diet in Unhealthy Cerebrovascular and Brain Aging: Mechanisms and Implications for Cognitive Impairment

Nutrients, 2023-11, Vol.15 (21), p.4662

2023

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Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase

American journal of physiology. Heart and circulatory physiology, 2014-02, Vol.306 (3), p.H299-H308

2014

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Pharmacological Strategies to Retard Cardiovascular Aging

Circulation research, 2016-05, Vol.118 (10), p.1626-1642

2016

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Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment

American journal of physiology. Heart and circulatory physiology, 2019-05, Vol.316 (5), p.H1124-H1140

2019

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Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation

GeroScience, 2018-12, Vol.40 (5-6), p.513-521

2018

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Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation

Frontiers in genetics, 2019-09, Vol.10, p.898-898

2019

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Resveratrol induces mitochondrial biogenesis in endothelial cells

American journal of physiology. Heart and circulatory physiology, 2009-07, Vol.297 (1), p.H13-H20

2009

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Functional vascular contributions to cognitive impairment and dementia: mechanisms and consequences of cerebral autoregulatory dysfunction, endothelial impairment, and neurovascular uncoupling in aging

Mechanisms of Vascular Aging

Hypertension-induced cognitive impairment: from pathophysiology to public health

Role of mitochondrial oxidative stress in hypertension

Increased cognitive workload evokes greater neurovascular coupling responses in healthy young adults

Impaired neurovascular coupling in aging and Alzheimer's disease: Contribution of astrocyte dysfunction and endothelial impairment to cognitive decline

Mitochondria and Cardiovascular Aging

Role of Vitamin D Deficiency in the Pathogenesis of Cardiovascular and Cerebrovascular Diseases

Role of endothelial NAD + deficiency in age-related vascular dysfunction

Cerebral microhemorrhages: mechanisms, consequences, and prevention

Age-Related Alterations in Gait Function in Freely Moving Male C57BL/6 Mice: Translational Relevance of Decreased Cadence and Increased Gait Variability

Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice

Endothelial Dysfunction and Impaired Neurovascular Coupling Responses Precede Cognitive Impairment in a Mouse Model of Geriatric Sepsis

Sleep deprivation impairs cognitive performance, alters task-associated cerebral blood flow and decreases cortical neurovascular coupling-related hemodynamic responses

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

Resveratrol attenuates mitochondrial oxidative stress in coronary arterial endothelial cells

Vascular mechanisms leading to progression of mild cognitive impairment to dementia after COVID-19: Protocol and methodology of a prospective longitudinal observational study

Nrf2 Deficiency Exacerbates Obesity-Induced Oxidative Stress, Neurovascular Dysfunction, Blood-Brain Barrier Disruption, Neuroinflammation, Amyloidogenic Gene Expression, and Cognitive Decline in Mice, Mimicking the Aging Phenotype

The Role of Methionine-Rich Diet in Unhealthy Cerebrovascular and Brain Aging: Mechanisms and Implications for Cognitive Impairment

Resveratrol treatment rescues neurovascular coupling in aged mice: role of improved cerebromicrovascular endothelial function and downregulation of NADPH oxidase

Pharmacological Strategies to Retard Cardiovascular Aging

Role of age-related alterations of the cerebral venous circulation in the pathogenesis of vascular cognitive impairment

Nrf2 deficiency in aged mice exacerbates cellular senescence promoting cerebrovascular inflammation

Potential Adverse Cardiovascular Effects of Treatment With Fluoxetine and Other Selective Serotonin Reuptake Inhibitors (SSRIs) in Patients With Geriatric Depression: Implications for Atherogenesis and Cerebromicrovascular Dysregulation

Resveratrol induces mitochondrial biogenesis in endothelial cells

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