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SLC9/NHE gene family, a plasma membrane and organellar family of Na+/H+ exchangers

Molecular aspects of medicine, 2013-04, Vol.34 (2-3), p.236-251

2013

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Type 1 diabetes human enteroid studies reveal major changes in the intestinal epithelial compartment

Scientific reports, 2024-05, Vol.14 (1), p.11911-11911, Article 11911

2024

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Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrhea

Human molecular genetics, 2015-12, Vol.24 (23), p.6614-6623

2015

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The Air-Liquid Interface Reorganizes Membrane Lipids and Enhances the Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colonoid Monolayers

International journal of molecular sciences, 2023-05, Vol.24 (9), p.8273

2023

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The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity

Biochemical journal, 2015-08, Vol.470 (1), p.77-90

2015

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Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling

American Journal of Physiology: Cell Physiology, 2014-07, Vol.307 (1), p.C55-C65

2014

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NHERF2/NHERF3 Protein Heterodimerization and Macrocomplex Formation Are Required for the Inhibition of NHE3 Activity by Carbachol

The Journal of biological chemistry, 2014-07, Vol.289 (29), p.20039-20053

2014

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NHERF family and NHE3 regulation

The Journal of physiology, 2005-08, Vol.567 (1), p.3-11

2005

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Nonsynonymous single nucleotide polymorphisms of NHE3 differentially decrease NHE3 transporter activity

American Journal of Physiology: Cell Physiology, 2015-05, Vol.308 (9), p.C758-C766

2015

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Enterohemorrhagic E. coli (EHEC)-Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers

Toxins, 2018-09, Vol.10 (9), p.351

2018

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Inhibition of CFTR‐mediated intestinal chloride secretion as potential therapy for bile acid diarrhea

The FASEB journal, 2019-10, Vol.33 (10), p.10924-10934

2019

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Cyclic GMP kinase II (cGKII) inhibits NHE3 by altering its trafficking and phosphorylating NHE3 at three required sites: identification of a multifunctional phosphorylation site

The Journal of biological chemistry, 2015-01, Vol.290 (4), p.1952-1965

2015

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Calmodulin Kinase II Constitutively Binds, Phosphorylates, and Inhibits Brush Border Na+/H+ Exchanger 3 (NHE3) by a NHERF2 Protein-dependent Process

The Journal of biological chemistry, 2012-04, Vol.287 (16), p.13442-13456

2012

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NHERF2 Protein Mobility Rate Is Determined by a Unique C-terminal Domain That Is Also Necessary for Its Regulation of NHE3 Protein in OK Cells

The Journal of biological chemistry, 2013-06, Vol.288 (23), p.16960-16974

2013

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CAM Kinase IIγ Inhibits Activity and Directly Binds the C-Terminal Domain of the Intestinal Brush Border Na/H Exchanger NHE3 in a Dymanic, Ca2+ Dependent Manner

Gastroenterology (New York, N.Y. 1943), 2011, Vol.140 (5), p.S-133-S-133

2011

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256 Myosin VI is Responsible for Movement of NHE3 From the Microvillus of Polarized Caco-2-bbe Cells to the Intervillus Clefts Under Basal Conditions and With Ca2+ Stimulated Endocytosis

Gastroenterology (New York, N.Y. 1943), 2010, Vol.138 (5), p.S-47-S-47

2010

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T1871 NHE3 Activity is Dependent on Direct Phosphatidylinositide Binding at Its Proximal Cytosolic Region

Gastroenterology (New York, N.Y. 1943), 2010, Vol.138 (5), p.S-596-S-596

2010

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Fr584 MUSCARINIC AND NICOTINIC PATHWAYS SYNERGISTICALLY REGULATE CHOLINERGIC-INDUCED ANION SECRETION BY NICOTINIC-INDUCED CROSS-OVER OF CA2+ AND CAMP SIGNALING IN MOUSE JEJUNAL ENTEROIDS

Gastroenterology (New York, N.Y. 1943), 2021-05, Vol.160 (6), p.S-373-S-373

2021

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266 NHE3 IS A DRUG TARGET FOR TREATING DIARRHE; A NOVEL PEPTIDE STIMULATES NHE3 ACTIVITY, PREVENTS CAMP, CGMP AND CA2+ INHIBITION OF NHE3 AND PREVENTS CHOLERA TOXIN AND E. COLI STABLE ENTEROTOXIN FLUID SECRETION

Gastroenterology (New York, N.Y. 1943), 2021-05, Vol.160 (6), p.S-63-S-64

2021

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Kinetics and regulation of three cloned mammalian Na+/H+ exchangers stably expressed in a fibroblast cell line

The Journal of biological chemistry, 1993-12, Vol.268 (34), p.25527-25535

1993

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Separate C-terminal Domains of the Epithelial Specific Brush Border Na+/H+ Exchanger Isoform NHE3 Are Involved in Stimulation and Inhibition by Protein Kinases/Growth Factors

The Journal of biological chemistry, 1995-06, Vol.270 (23), p.13716-13725

1995

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Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger

The EMBO journal, 1991-08, Vol.10 (8), p.1957-1967

1991

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Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKC[Delta] signaling

American Journal of Physiology: Cell Physiology, 2014-07, Vol.307 (1), p.C55

2014

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Cyclic GMP Kinase II (cGKII) Inhibits NHE3 by Altering Its Trafficking and Phosphorylating NHE3 at Three Required Sites

The Journal of biological chemistry, 2015-01, Vol.290 (4), p.1952-1965

2015

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Leu143 in the Putative Fourth Membrane Spanning Domain Is Critical for Amiloride Inhibition of an Epithelial Na+/H+ Exchanger Isoform (NHE-2)

Biochemical and biophysical research communications, 1993-06, Vol.193 (2), p.532-539

1993

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SLC9/NHE gene family, a plasma membrane and organellar family of Na+/H+ exchangers

Type 1 diabetes human enteroid studies reveal major changes in the intestinal epithelial compartment

Reduced sodium/proton exchanger NHE3 activity causes congenital sodium diarrhea

The Air-Liquid Interface Reorganizes Membrane Lipids and Enhances the Recruitment of Slc26a3 to Lipid-Rich Domains in Human Colonoid Monolayers

The NHERF2 sequence adjacent and upstream of the ERM-binding domain affects NHERF2-ezrin binding and dexamethasone stimulated NHE3 activity

Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKCδ signaling

NHERF2/NHERF3 Protein Heterodimerization and Macrocomplex Formation Are Required for the Inhibition of NHE3 Activity by Carbachol

NHERF family and NHE3 regulation

Nonsynonymous single nucleotide polymorphisms of NHE3 differentially decrease NHE3 transporter activity

Enterohemorrhagic E. coli (EHEC)-Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers

Inhibition of CFTR‐mediated intestinal chloride secretion as potential therapy for bile acid diarrhea

Cyclic GMP kinase II (cGKII) inhibits NHE3 by altering its trafficking and phosphorylating NHE3 at three required sites: identification of a multifunctional phosphorylation site

Calmodulin Kinase II Constitutively Binds, Phosphorylates, and Inhibits Brush Border Na+/H+ Exchanger 3 (NHE3) by a NHERF2 Protein-dependent Process

NHERF2 Protein Mobility Rate Is Determined by a Unique C-terminal Domain That Is Also Necessary for Its Regulation of NHE3 Protein in OK Cells

CAM Kinase IIγ Inhibits Activity and Directly Binds the C-Terminal Domain of the Intestinal Brush Border Na/H Exchanger NHE3 in a Dymanic, Ca2+ Dependent Manner

256 Myosin VI is Responsible for Movement of NHE3 From the Microvillus of Polarized Caco-2-bbe Cells to the Intervillus Clefts Under Basal Conditions and With Ca2+ Stimulated Endocytosis

T1871 NHE3 Activity is Dependent on Direct Phosphatidylinositide Binding at Its Proximal Cytosolic Region

Fr584 MUSCARINIC AND NICOTINIC PATHWAYS SYNERGISTICALLY REGULATE CHOLINERGIC-INDUCED ANION SECRETION BY NICOTINIC-INDUCED CROSS-OVER OF CA2+ AND CAMP SIGNALING IN MOUSE JEJUNAL ENTEROIDS

266 NHE3 IS A DRUG TARGET FOR TREATING DIARRHE; A NOVEL PEPTIDE STIMULATES NHE3 ACTIVITY, PREVENTS CAMP, CGMP AND CA2+ INHIBITION OF NHE3 AND PREVENTS CHOLERA TOXIN AND E. COLI STABLE ENTEROTOXIN FLUID SECRETION

Kinetics and regulation of three cloned mammalian Na+/H+ exchangers stably expressed in a fibroblast cell line

Separate C-terminal Domains of the Epithelial Specific Brush Border Na+/H+ Exchanger Isoform NHE3 Are Involved in Stimulation and Inhibition by Protein Kinases/Growth Factors

Molecular cloning and expression of a cDNA encoding the rabbit ileal villus cell basolateral membrane Na+/H+ exchanger

Lysophosphatidic acid stimulation of NHE3 exocytosis in polarized epithelial cells occurs with release from NHERF2 via ERK-PLC-PKC[Delta] signaling

Cyclic GMP Kinase II (cGKII) Inhibits NHE3 by Altering Its Trafficking and Phosphorylating NHE3 at Three Required Sites

Leu143 in the Putative Fourth Membrane Spanning Domain Is Critical for Amiloride Inhibition of an Epithelial Na+/H+ Exchanger Isoform (NHE-2)

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