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Small-Molecule PROTACS: New Approaches to Protein Degradation

Angewandte Chemie (International ed.), 2016-02, Vol.55 (6), p.1966-1973

International ed. in English, 2016

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Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL

Angewandte Chemie (International ed.), 2016-01, Vol.55 (2), p.807-810

International ed. in English, 2016

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Targeting the C481S Ibrutinib-Resistance Mutation in Bruton’s Tyrosine Kinase Using PROTAC-Mediated Degradation

Biochemistry (Easton), 2018-07, Vol.57 (26), p.3564-3575

2018

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Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response

Molecular biology of the cell, 2018-06, Vol.29 (11), p.1284-1298

2018

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Niedermolekulare PROTACs: neue Wege zum Abbau von Proteinen

Angewandte Chemie, 2016-02, Vol.128 (6), p.2002-2010

2016

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Straightforward and Controlled Shape Access to Efficient Macrocyclic Imidazolylboronium Anion Receptors

Chemistry : a European journal, 2016-06, Vol.22 (26), p.8937-8942

2016

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Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties

Bioorganic & medicinal chemistry letters, 2020-02, Vol.30 (3), p.126877-126877, Article 126877

2020

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The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

Cell chemical biology, 2018-01, Vol.25 (1), p.67-77.e3

2018

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Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation

ACS chemical biology, 2017-10, Vol.12 (10), p.2570-2578

2017

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Synthesis and structure of Ag(I), Pd(II), Rh(I), Ru(II) and Au(I) NHC-complexes with a pendant Lewis acidic boronic ester moiety

Dalton transactions : an international journal of inorganic chemistry, 2015-04, Vol.44 (16), p.7139-7143

2015

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Asymmetric Rhodium-Directed anti-Markovnikov Regioselective Boracyclopentannulation

Journal of the American Chemical Society, 2012-10, Vol.134 (43), p.17892-17895

2012

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Synthesis and structure of Ag(i), Pd(ii), Rh(i), Ru(ii) and Au(i) NHC-complexes with a pendant Lewis acidic boronic ester moietyElectronic supplementary information (ESI) available: Experimental procedures, spectroscopic data, detailed calculations and CIF for complexes 5a, 5b, 6a, 7a and 7b. CCDC 864270, 880506, 880508, 1023303 and 1023304. For ESI and crystallographic data in CIF or other electronic format see DOI: 10.1039/c5dt00814j

2015-04

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Expeditious Synthesis of Isoquinolones and Isocoumarins with a Vinyl Borane as an Acetylene Equivalent

European journal of organic chemistry, 2016-08, Vol.2016 (24), p.4171-4175

2016

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Discovery of quinazoline HPK1 inhibitors with high cellular potency

Bioorganic & medicinal chemistry, 2023-09, Vol.92, p.117423-117423, Article 117423

2023

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Niedermolekulare PROTACs: neue Wege zum Abbau von Proteinen

Angewandte Chemie, 2016-02, Vol.128 (6), p.2002-2010

2016

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Investigation of the rhodium-catalyzed hydroboration of NHC-boranes: the role of alkene coordination and the origin of enantioselectivity

Dalton transactions : an international journal of inorganic chemistry, 2019-12, Vol.48 (47), p.1765-17611

2019

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Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure–Degradation Relationships

ChemMedChem, 2018-08, Vol.13 (15), p.1508-1512

2018

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Modulares PROTAC-Design zum Abbau von onkogenem BCR-ABL

Angewandte Chemie, 2016-01, Vol.128 (2), p.818-821

2016

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Chemical functionalization of electrodes for detection of gaseous nerve agents with carbon nanotube field-effect transistors

Chemical communications (Cambridge, England), 2011-01, Vol.47 (21), p.6048-6050

2011

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Modulares PROTAC‐Design zum Abbau von onkogenem BCR‐ABL

Angewandte Chemie, 2016-01, Vol.128 (2), p.818-821

2016

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ChemInform Abstract: Small‐Molecule PROTACS: New Approaches to Protein Degradation

ChemInform, 2016-03, Vol.47 (13), p.no-no

2016

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ChemInform Abstract: Expeditious Synthesis of Isoquinolones and Isocoumarins with a Vinyl Borane as an Acetylene Equivalent

ChemInform, 2016-12, Vol.47 (52), p.no-no

2016

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ChemInform Abstract: Asymmetric Rhodium-Directed anti-Markovnikov Regioselective Boracyclopentannulation

ChemInform, 2013-05, Vol.44 (20), p.no-no

2013

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ChemInform Abstract: Chemical Functionalization of Electrodes for Detection of Gaseous Nerve Agents with Carbon Nanotube Field-Effect Transistors

ChemInform, 2011-08, Vol.42 (35), p.no-no

2011

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Small-Molecule PROTACS: New Approaches to Protein Degradation

Modular PROTAC Design for the Degradation of Oncogenic BCR-ABL

Targeting the C481S Ibrutinib-Resistance Mutation in Bruton’s Tyrosine Kinase Using PROTAC-Mediated Degradation

Targeted protein unfolding uncovers a Golgi-specific transcriptional stress response

Niedermolekulare PROTACs: neue Wege zum Abbau von Proteinen

Straightforward and Controlled Shape Access to Efficient Macrocyclic Imidazolylboronium Anion Receptors

Design, synthesis and biological evaluation of Proteolysis Targeting Chimeras (PROTACs) as a BTK degraders with improved pharmacokinetic properties

The Advantages of Targeted Protein Degradation Over Inhibition: An RTK Case Study

Assessing Different E3 Ligases for Small Molecule Induced Protein Ubiquitination and Degradation

Synthesis and structure of Ag(I), Pd(II), Rh(I), Ru(II) and Au(I) NHC-complexes with a pendant Lewis acidic boronic ester moiety

Asymmetric Rhodium-Directed anti-Markovnikov Regioselective Boracyclopentannulation

Expeditious Synthesis of Isoquinolones and Isocoumarins with a Vinyl Borane as an Acetylene Equivalent

Discovery of quinazoline HPK1 inhibitors with high cellular potency

Niedermolekulare PROTACs: neue Wege zum Abbau von Proteinen

Investigation of the rhodium-catalyzed hydroboration of NHC-boranes: the role of alkene coordination and the origin of enantioselectivity

Efficient Synthesis of Immunomodulatory Drug Analogues Enables Exploration of Structure–Degradation Relationships

Modulares PROTAC-Design zum Abbau von onkogenem BCR-ABL

Chemical functionalization of electrodes for detection of gaseous nerve agents with carbon nanotube field-effect transistors

Modulares PROTAC‐Design zum Abbau von onkogenem BCR‐ABL

ChemInform Abstract: Small‐Molecule PROTACS: New Approaches to Protein Degradation

ChemInform Abstract: Expeditious Synthesis of Isoquinolones and Isocoumarins with a Vinyl Borane as an Acetylene Equivalent

ChemInform Abstract: Asymmetric Rhodium-Directed anti-Markovnikov Regioselective Boracyclopentannulation

ChemInform Abstract: Chemical Functionalization of Electrodes for Detection of Gaseous Nerve Agents with Carbon Nanotube Field-Effect Transistors

Hepatitis E Virus Seroprevalence and Associated Risk Factors in Pregnant Women Attending Antenatal Consultations in Senegal

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