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APP Osaka Mutation in Familial Alzheimer's Disease-Its Discovery, Phenotypes, and Mechanism of Recessive Inheritance

International journal of molecular sciences, 2020-02, Vol.21 (4), p.1413

2020

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Nasal Rifampicin Improves Cognition in a Mouse Model of Dementia with Lewy Bodies by Reducing α-Synuclein Oligomers

International journal of molecular sciences, 2021-08, Vol.22 (16), p.8453

2021

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Oligomer-Targeting Prevention of Neurodegenerative Dementia by Intranasal Rifampicin and Resveratrol Combination - A Preclinical Study in Model Mice

Frontiers in neuroscience, 2021-12, Vol.15, p.763476-763476

2021

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Longitudinal, Quantitative Assessment of Amyloid, Neuroinflammation, and Anti-Amyloid Treatment in a Living Mouse Model of Alzheimer's Disease Enabled by Positron Emission Tomography

The Journal of neuroscience, 2007-10, Vol.27 (41), p.10957-10968

2007

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Hawaiian native herb Mamaki prevents dementia by ameliorating neuropathology and repairing neurons in four different mouse models of neurodegenerative diseases

GeroScience, 2024-04, Vol.46 (2), p.1971-1987

2024

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Fluorine-19 Magnetic Resonance Imaging for Detection of Amyloid β Oligomers Using a Keto Form of Curcumin Derivative in a Mouse Model of Alzheimer's Disease

Molecules (Basel, Switzerland), 2021-03, Vol.26 (5), p.1362

2021

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Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain

Journal of nanobiotechnology, 2023-01, Vol.21 (1), p.36-36, Article 36

2023

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Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain

The Journal of neuroscience, 2019-08, Vol.39 (34), p.6781-6797

2019

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Nasal Rifampicin Halts the Progression of Tauopathy by Inhibiting Tau Oligomer Propagation in Alzheimer Brain Extract-Injected Mice

Biomedicines, 2022-01, Vol.10 (2), p.297

2022

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Heavy Tau Burden with Subtle Amyloid β Accumulation in the Cerebral Cortex and Cerebellum in a Case of Familial Alzheimer's Disease with APP Osaka Mutation

International journal of molecular sciences, 2020-06, Vol.21 (12), p.4443

2020

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Decreased levels of PDI and P5 in oligodendrocytes in Alzheimer's disease

Neuropathology, 2017-12, Vol.37 (6), p.495-501

2017

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The domestic cat as a natural animal model of Alzheimer's disease

Acta neuropathologica communications, 2015-12, Vol.3 (1), p.78-78, Article 78

2015

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Increased GADD34 in oligodendrocytes in Alzheimer’s disease

Neuroscience letters, 2015-08, Vol.602, p.50-55

2015

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Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A2 in a spatial-specific manner

Acta neuropathologica communications, 2017-07, Vol.5 (1), p.1-17, Article 56

2017

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C9orf72 Hexanucleotide Repeat Expansion-Related Neuropathology Is Attenuated by Nasal Rifampicin in Mice

Biomedicines, 2022-05, Vol.10 (5), p.1080

2022

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Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease

PloS one, 2017-04, Vol.12 (4), p.e0174630-e0174630

2017

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Passive immunotherapy of tauopathy targeting pSer413‐tau: a pilot study in mice

Annals of clinical and translational neurology, 2015-03, Vol.2 (3), p.241-255

2015

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Intranasal rifampicin for Alzheimer's disease prevention

Alzheimer's & dementia : translational research & clinical interventions, 2018, Vol.4 (1), p.304-313

2018

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Proteomic analysis of the hippocampus in Alzheimer's disease model mice by using two-dimensional fluorescence difference in gel electrophoresis

Neuroscience letters, 2013-02, Vol.534, p.85-89

2013

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Improved Long-Term Potentiation and Memory in Young Tau-P301L Transgenic Mice before Onset of Hyperphosphorylation and Tauopathy

The Journal of neuroscience, 2006-03, Vol.26 (13), p.3514-3523

2006

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Rivastigmine Improves Appetite by Increasing the Plasma Acyl/Des-Acyl Ghrelin Ratio and Cortisol in Alzheimer Disease

Dementia and geriatric cognitive disorders extra, 2018-01, Vol.8 (1), p.77-84

2018

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Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer's disease: analysis of Osaka mutation-knockin mice

Acta neuropathologica communications, 2017-07, Vol.5 (1), p.59-59, Article 59

2017

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Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo

Journal of neuropathology and experimental neurology, , Vol.63 (3), p.255-261

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Syntaxin 5 Isoforms Syx5 and Syx5L have Distinct Effects on the Processing of β-amyloid Precursor Protein

Journal of biochemistry (Tokyo), 2009-12, Vol.146 (6), p.905-915

2009

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Mutations in the β-amyloid precursor protein in familial Alzheimer’s disease increase Aβ oligomer production in cellular models

Heliyon, 2018-01, Vol.4 (1), p.e00511-e00511, Article e00511

2018

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APP Osaka Mutation in Familial Alzheimer's Disease-Its Discovery, Phenotypes, and Mechanism of Recessive Inheritance

Nasal Rifampicin Improves Cognition in a Mouse Model of Dementia with Lewy Bodies by Reducing α-Synuclein Oligomers

Oligomer-Targeting Prevention of Neurodegenerative Dementia by Intranasal Rifampicin and Resveratrol Combination - A Preclinical Study in Model Mice

Longitudinal, Quantitative Assessment of Amyloid, Neuroinflammation, and Anti-Amyloid Treatment in a Living Mouse Model of Alzheimer's Disease Enabled by Positron Emission Tomography

Hawaiian native herb Mamaki prevents dementia by ameliorating neuropathology and repairing neurons in four different mouse models of neurodegenerative diseases

Fluorine-19 Magnetic Resonance Imaging for Detection of Amyloid β Oligomers Using a Keto Form of Curcumin Derivative in a Mouse Model of Alzheimer's Disease

Peripheral administration of nanomicelle-encapsulated anti-Aβ oligomer fragment antibody reduces various toxic Aβ species in the brain

Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain

Nasal Rifampicin Halts the Progression of Tauopathy by Inhibiting Tau Oligomer Propagation in Alzheimer Brain Extract-Injected Mice

Heavy Tau Burden with Subtle Amyloid β Accumulation in the Cerebral Cortex and Cerebellum in a Case of Familial Alzheimer's Disease with APP Osaka Mutation

Decreased levels of PDI and P5 in oligodendrocytes in Alzheimer's disease

The domestic cat as a natural animal model of Alzheimer's disease

Increased GADD34 in oligodendrocytes in Alzheimer’s disease

Oligomeric amyloid-beta induces MAPK-mediated activation of brain cytosolic and calcium-independent phospholipase A2 in a spatial-specific manner

C9orf72 Hexanucleotide Repeat Expansion-Related Neuropathology Is Attenuated by Nasal Rifampicin in Mice

Aβ levels in the jugular vein and high molecular weight Aβ oligomer levels in CSF can be used as biomarkers to indicate the anti-amyloid effect of IVIg for Alzheimer's disease

Passive immunotherapy of tauopathy targeting pSer413‐tau: a pilot study in mice

Intranasal rifampicin for Alzheimer's disease prevention

Proteomic analysis of the hippocampus in Alzheimer's disease model mice by using two-dimensional fluorescence difference in gel electrophoresis

Improved Long-Term Potentiation and Memory in Young Tau-P301L Transgenic Mice before Onset of Hyperphosphorylation and Tauopathy

Rivastigmine Improves Appetite by Increasing the Plasma Acyl/Des-Acyl Ghrelin Ratio and Cortisol in Alzheimer Disease

Mutation-induced loss of APP function causes GABAergic depletion in recessive familial Alzheimer's disease: analysis of Osaka mutation-knockin mice

Amyloid beta peptide-induced cerebral neuronal loss is mediated by caspase-3 in vivo

Syntaxin 5 Isoforms Syx5 and Syx5L have Distinct Effects on the Processing of β-amyloid Precursor Protein

Mutations in the β-amyloid precursor protein in familial Alzheimer’s disease increase Aβ oligomer production in cellular models

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