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Roscovitine Targets, Protein Kinases and Pyridoxal Kinase[boxs]

The Journal of biological chemistry, 2005-09, Vol.280 (35), p.31208-31219

2005

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7-Bromoindirubin-3′-oxime induces caspase-independent cell death

Oncogene, 2006-10, Vol.25 (47), p.6304-6318

2006

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Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases

Biochemistry (Moscow), 2018-10, Vol.83 (10), p.1222-1230

2018

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170 A High-throughput Capable Method to Identify Allosteric Inhibitors of Protein Kinase Activation Cascades

European journal of cancer (1990), 2012-11, Vol.48, p.52-52

2012

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173 Analysis of Cellular Kinase Activity of Resistance-related EGFR Mutants Using Transmembrane-Domain (TMD) Activated Kinase Variants

European journal of cancer (1990), 2012-11, Vol.48, p.53-53

2012

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Novel CDK inhibition profiles of structurally varied 1-aza-9-oxafluorenes

Bioorganic & medicinal chemistry letters, 2005-02, Vol.15 (3), p.823-825

2005

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1251 POSTER Preclinical and Clinical Development of 4SC-203 – a Novel Multi-target Kinase Inhibitor

European journal of cancer (1990), 2011, Vol.47, p.S160-S160

2011

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Flavopiridol protects against inflammation by attenuating leukocyte-endothelial interaction via inhibition of cyclin-dependent kinase 9

Arteriosclerosis, thrombosis, and vascular biology, 2011-02, Vol.31 (2), p.280

2011

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PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration

Cancer research (Chicago, Ill.), 2000-04, Vol.60 (8), p.2178-2189

2000

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Design, Synthesis, and Biological Evaluation of 3,4-Diarylmaleimides as Angiogenesis Inhibitors

Journal of medicinal chemistry, 2006-02, Vol.49 (4), p.1271-1281

2006

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Mapping of the Sites for Ligand Binding and Receptor Dimerization at the Extracellular Domain of the Vascular Endothelial Growth Factor Receptor FLT-1

The Journal of biological chemistry, 1997-04, Vol.272 (16), p.10382-10388

1997

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Matrix compare analysis discriminates subtle structural differences in a family of novel antiproliferative agents, diaryl-3-hydroxy-2,3,3a,10a-tetrahydrobenzo[ b]cycylopenta[ e]azepine-4,10(1 H,5 H)-diones

Bioorganic & medicinal chemistry letters, 2006-04, Vol.16 (8), p.2148-2153

2006

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Structure-Aided Optimization of Kinase Inhibitors Derived from Alsterpaullone

Chembiochem : a European journal of chemical biology, 2005-03, Vol.6 (3), p.541-549

2005

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Soluble VEGFR-1 secreted by endothelial cells and monocytes is present in human serum and plasma from healthy donors

Angiogenesis (London), 2001, Vol.4 (2), p.143-154

2001

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Diversity-Oriented Synthesis of Pochonins and Biological Evaluation against a Panelof Kinases

Chemistry : a European journal, 2006, Vol.12 (34)

2006

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Anthraquinones and Betaenone Derivatives from the Sponge-Associated Fungus Microsphaeropsis Species: Novel Inhibitors of Protein Kinases

Journal of natural products (Washington, D.C.), 2000-06, Vol.63 (6), p.739-745

2000

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The Drosophila melanogaster l(2)gl gene encodes a protein homologous to the cadherin cell-adhesion molecule family

Developmental biology, 1989-06, Vol.133 (2), p.425-436

1989

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Over-expression of protein kinase C-α enhances platelet-derived growth factor- and phorbol ester- but not calcium ionophore-induced formation of prostaglandins in NIH 3T3 fibroblasts

FEBS letters, 1993-04, Vol.321 (1), p.11-14

1993

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Over-expression of human phospholipase C-gamma 2 enhances platelet-derived growth factor-induced mobilization of intracellular Ca2+ and the release of arachidonic acid and prostaglandins in NIH 3T3 fibroblasts

FEBS letters, 1992-08, Vol.308 (2), p.125-129

1992

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Inducible expression of human phospholipase C- gamma 2 and its activation by platelet-derived growth factor B-chain homodimer and platelet-derived growth factor A-chain homodimer in transfected NIH 3T3 fibroblasts

European journal of biochemistry, 1992-01, Vol.203 (3), p.663-639

1992

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Inducible expression of human phospholipase C‐γ2 and its activation by platelet‐derived growth factor B‐chain homodimer and platelet‐derived growth factor A‐chain homodimer in transfected NIH 3T3 fibroblasts

European journal of biochemistry, 1992-02, Vol.203 (3), p.633-639

1992

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Inducible expression of human phospholipase C-gamma 2 and its activation by platelet-derived growth factor B-chain homodimer and platelet-derived growth factor A-chain homodimer in transfected NIH 3T3 fibroblasts

European journal of biochemistry, 1992-02, Vol.203 (3), p.633-639

1992

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Robot Screening: A New Dimension in Target-Oriented Drug Discovery

Relevance of Tumor Models for Anticancer Drug Development, 1999, Vol.54, p.249-260

1999

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Behavioral adaptation caused by predictive warning systems – The case of congestion tail warnings

Transportation research. Part F, Traffic psychology and behaviour, 2014-09, Vol.26, p.49-61

2014

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Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease

Cell chemical biology, 2017-08, Vol.24 (8), p.1029-1039.e7

2017

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Roscovitine Targets, Protein Kinases and Pyridoxal Kinase[boxs]

7-Bromoindirubin-3′-oxime induces caspase-independent cell death

Hydrophobic Derivatives of Glycopeptide Antibiotics as Inhibitors of Protein Kinases

170 A High-throughput Capable Method to Identify Allosteric Inhibitors of Protein Kinase Activation Cascades

173 Analysis of Cellular Kinase Activity of Resistance-related EGFR Mutants Using Transmembrane-Domain (TMD) Activated Kinase Variants

Novel CDK inhibition profiles of structurally varied 1-aza-9-oxafluorenes

1251 POSTER Preclinical and Clinical Development of 4SC-203 – a Novel Multi-target Kinase Inhibitor

Flavopiridol protects against inflammation by attenuating leukocyte-endothelial interaction via inhibition of cyclin-dependent kinase 9

PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration

Design, Synthesis, and Biological Evaluation of 3,4-Diarylmaleimides as Angiogenesis Inhibitors

Mapping of the Sites for Ligand Binding and Receptor Dimerization at the Extracellular Domain of the Vascular Endothelial Growth Factor Receptor FLT-1

Matrix compare analysis discriminates subtle structural differences in a family of novel antiproliferative agents, diaryl-3-hydroxy-2,3,3a,10a-tetrahydrobenzo[ b]cycylopenta[ e]azepine-4,10(1 H,5 H)-diones

Structure-Aided Optimization of Kinase Inhibitors Derived from Alsterpaullone

Soluble VEGFR-1 secreted by endothelial cells and monocytes is present in human serum and plasma from healthy donors

Diversity-Oriented Synthesis of Pochonins and Biological Evaluation against a Panelof Kinases

Anthraquinones and Betaenone Derivatives from the Sponge-Associated Fungus Microsphaeropsis Species: Novel Inhibitors of Protein Kinases

The Drosophila melanogaster l(2)gl gene encodes a protein homologous to the cadherin cell-adhesion molecule family

Over-expression of protein kinase C-α enhances platelet-derived growth factor- and phorbol ester- but not calcium ionophore-induced formation of prostaglandins in NIH 3T3 fibroblasts

Over-expression of human phospholipase C-gamma 2 enhances platelet-derived growth factor-induced mobilization of intracellular Ca2+ and the release of arachidonic acid and prostaglandins in NIH 3T3 fibroblasts

Inducible expression of human phospholipase C- gamma 2 and its activation by platelet-derived growth factor B-chain homodimer and platelet-derived growth factor A-chain homodimer in transfected NIH 3T3 fibroblasts

Inducible expression of human phospholipase C‐γ2 and its activation by platelet‐derived growth factor B‐chain homodimer and platelet‐derived growth factor A‐chain homodimer in transfected NIH 3T3 fibroblasts

Inducible expression of human phospholipase C-gamma 2 and its activation by platelet-derived growth factor B-chain homodimer and platelet-derived growth factor A-chain homodimer in transfected NIH 3T3 fibroblasts

Robot Screening: A New Dimension in Target-Oriented Drug Discovery

Behavioral adaptation caused by predictive warning systems – The case of congestion tail warnings

Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-α Inhibition for Cancer and Autoimmune Disease

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