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The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems

PloS one, 2023-06, Vol.18 (6), p.e0287461-e0287461

2023

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Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition

The Journal of biological chemistry, 2019-11, Vol.294 (46), p.17642-17653

2019

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TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization

The EMBO journal, 2015-03, Vol.34 (6), p.811-827

2015

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Oligomer Formation by Amyloid-β42 in a Membrane-Mimicking Environment in Alzheimer's Disease

Molecules (Basel, Switzerland), 2022-12, Vol.27 (24), p.8804

2022

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Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

eLife, 2019-05, Vol.8

2019

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Structural Basis for Cargo Regulation of COPII Coat Assembly

Cell, 2008-08, Vol.134 (3), p.474-484

2008

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trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo

Nature communications, 2021-03, Vol.12 (1), p.1799-12, Article 1799

2021

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Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex

Cell reports (Cambridge), 2014-12, Vol.9 (5), p.1610-1617

2014

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Structure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5 Å Resolution

Structure (London), 2012-08, Vol.20 (8), p.1310-1320

2012

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Cryo-EM Structures of the Actin:Tropomyosin Filament Reveal the Mechanism for the Transition from C- to M-State

Journal of molecular biology, 2013-11, Vol.425 (22), p.4544-4555

2013

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A pseudoatomic model of the COPII cage obtained from cryo-electron microscopy and mass spectrometry

Nature structural & molecular biology, 2013-02, Vol.20 (2), p.167

2013

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The Structure of the Sec13/31 COPII Cage Bound to Sec23

Journal of molecular biology, 2012-07, Vol.420 (4-5), p.324-334

2012

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Probing intracellular vesicle trafficking and membrane remodelling by cryo-EM

Journal of structural biology, 2022-03, Vol.214 (1), p.107836-107836, Article 107836

2022

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Cryo-electron Microscopy of Adeno-associated Virus

Chemical reviews, 2022-09, Vol.122 (17), p.14018-14054

2022

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Study of the Structural Dynamics of the E. coli 70S Ribosome Using Real-Space Refinement

Cell, 2003-06, Vol.113 (6), p.789-801

2003

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Characterizing the resolution and throughput of the Apollo direct electron detector

Journal of structural biology. X, 2023-01, Vol.7 (C), p.100080-100080, Article 100080

2023

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Pathogenic TFG Mutations Underlying Hereditary Spastic Paraplegia Impair Secretory Protein Trafficking and Axon Fasciculation

Cell reports (Cambridge), 2018-08, Vol.24 (9), p.2248-2260

2018

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Reconstruction of Average Subtracted Tubular Regions (RASTR) enables structure determination of tubular filaments by cryo-EM

Journal of structural biology. X, 2020-01, Vol.4, p.100023-100023, Article 100023

2020

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Automated batch fiducial-less tilt-series alignment in Appion using Protomo

Journal of structural biology, 2015-11, Vol.192 (2), p.270-278

2015

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The 2.8 Å Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide

Molecular therapy. Methods & clinical development, 2017-06, Vol.5 (C), p.1-12

2017

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Cleavage and Structural Transitions during Maturation of Staphylococcus aureus Bacteriophage 80α and SaPI1 Capsids

Viruses, 2017-12, Vol.9 (12), p.384

2017

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Adeno-Associated Virus Receptor-Binding: Flexible Domains and Alternative Conformations through Cryo-Electron Tomography of Adeno-Associated Virus 2 (AAV2) and AAV5 Complexes

Journal of virology, 2022-07, Vol.96 (13), p.e0010622-e0010622

2022

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Appion: An integrated, database-driven pipeline to facilitate EM image processing

Journal of structural biology, 2009-04, Vol.166 (1), p.95-102

2009

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Processing apoferritin with the Appion pipeline

Journal of structural biology, 2018-10, Vol.204 (1), p.85-89

2018

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Assessing the quality of single particle reconstructions by atomic model building

Journal of structural biology, 2018-11, Vol.204 (2), p.276-282

2018

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The structure of a Type III-A CRISPR-Cas effector complex reveals conserved and idiosyncratic contacts to target RNA and crRNA among Type III-A systems

Functionally critical residues in the aminoglycoside resistance-associated methyltransferase RmtC play distinct roles in 30S substrate recognition

TFG clusters COPII-coated transport carriers and promotes early secretory pathway organization

Oligomer Formation by Amyloid-β42 in a Membrane-Mimicking Environment in Alzheimer's Disease

Structure of the gene therapy vector, adeno-associated virus with its cell receptor, AAVR

Structural Basis for Cargo Regulation of COPII Coat Assembly

trans-Translation inhibitors bind to a novel site on the ribosome and clear Neisseria gonorrhoeae in vivo

Essential structural and functional roles of the Cmr4 subunit in RNA cleavage by the Cmr CRISPR-Cas complex

Structure of AAV-DJ, a Retargeted Gene Therapy Vector: Cryo-Electron Microscopy at 4.5 Å Resolution

Cryo-EM Structures of the Actin:Tropomyosin Filament Reveal the Mechanism for the Transition from C- to M-State

A pseudoatomic model of the COPII cage obtained from cryo-electron microscopy and mass spectrometry

The Structure of the Sec13/31 COPII Cage Bound to Sec23

Probing intracellular vesicle trafficking and membrane remodelling by cryo-EM

Cryo-electron Microscopy of Adeno-associated Virus

Study of the Structural Dynamics of the E. coli 70S Ribosome Using Real-Space Refinement

Characterizing the resolution and throughput of the Apollo direct electron detector

Pathogenic TFG Mutations Underlying Hereditary Spastic Paraplegia Impair Secretory Protein Trafficking and Axon Fasciculation

Reconstruction of Average Subtracted Tubular Regions (RASTR) enables structure determination of tubular filaments by cryo-EM

Automated batch fiducial-less tilt-series alignment in Appion using Protomo

The 2.8 Å Electron Microscopy Structure of Adeno-Associated Virus-DJ Bound by a Heparinoid Pentasaccharide

Cleavage and Structural Transitions during Maturation of Staphylococcus aureus Bacteriophage 80α and SaPI1 Capsids

Adeno-Associated Virus Receptor-Binding: Flexible Domains and Alternative Conformations through Cryo-Electron Tomography of Adeno-Associated Virus 2 (AAV2) and AAV5 Complexes

Appion: An integrated, database-driven pipeline to facilitate EM image processing

Processing apoferritin with the Appion pipeline

Assessing the quality of single particle reconstructions by atomic model building

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