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Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options

Leukemia, 2019-05, Vol.33 (5), p.1063-1075

2019

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A loss-of-adhesion CRISPR-Cas9 screening platform to identify cell adhesion-regulatory proteins and signaling pathways

Nature communications, 2022-04, Vol.13 (1), p.2136-2136, Article 2136

2022

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The clinically active BTK inhibitor PCI-32765 targets B-cell receptor– and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia

Blood, 2012-03, Vol.119 (11), p.2590-2594

2012

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What's brewing for MALT1 in lymphoma?

Blood, 2023-12, Vol.142 (23), p.1939-1941

Spaargaren, Marcel

2023

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Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma

Leukemia, 2021-03, Vol.35 (3), p.881-886

2021

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MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance

Gastroenterology (New York, N.Y. 1943), 2019-10, Vol.157 (4), p.1153-1155.e1

2019

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MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis

Haematologica (Roma), 2020-02, Vol.105 (2), p.424-434

2020

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Heparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myeloma

The FEBS journal, 2013-05, Vol.280 (10), p.2180-2193

2013

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Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation

Haematologica (Roma), 2023-03, Vol.108 (3), p.797-810

2023

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Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations

Blood, 2021-09, Vol.138 (13), p.1194-1197

2021

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The forkhead transcription factor FOXP1 represses human plasma cell differentiation

Blood, 2015-10, Vol.126 (18), p.2098-2109

2015

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Bruton's Tyrosine Kinase and Phospholipase Cγ2 Mediate Chemokine-Controlled B Cell Migration and Homing

Immunity (Cambridge, Mass.), 2007, Vol.26 (1), p.93-104

2007

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The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma

British journal of cancer, 2019-06, Vol.120 (12), p.1137-1146

2019

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Lymphoma dissemination: the other face of lymphocyte homing

Blood, 2007-11, Vol.110 (9), p.3102-3111

2007

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The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

Journal of hematology and oncology, 2021-01, Vol.14 (1), p.11-11, Article 11

2021

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Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis

Cancer research (Chicago, Ill.), 2008-05, Vol.68 (10), p.3655-3661

2008

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Ibrutinib and idelalisib target B cell receptor- but not CXCL12/CXCR4-controlled integrin-mediated adhesion in Waldenström macroglobulinemia

Haematologica (Roma), 2016-03, Vol.101 (3), p.e111-e115

2016

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The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain

Blood cancer journal (New York), 2023-08, Vol.13 (1), p.125-125, Article 125

2023

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MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas

Blood cancer journal (New York), 2023-03, Vol.13 (1), p.37-37, Article 37

2023

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Correction to: The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

Journal of hematology and oncology, 2021-02, Vol.14 (1), p.29-29, Article 29

2021

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Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies

Oncogenesis (New York, NY), 2023-02, Vol.12 (1), p.6-6, Article 6

2023

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Illegitimate WNT Signaling Promotes Proliferation of Multiple Myeloma Cells

Proceedings of the National Academy of Sciences - PNAS, 2004-04, Vol.101 (16), p.6122-6127

2004

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Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma

PloS one, 2012-02, Vol.7 (2), p.e30359

2012

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The HGF/MET pathway as target for the treatment of multiple myeloma and B-cell lymphomas

Biochimica et biophysica acta, 2010-12, Vol.1806 (2), p.208-219

2010

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The small FOXP1 isoform predominantly expressed in activated B cell-like diffuse large B-cell lymphoma and full-length FOXP1 exert similar oncogenic and transcriptional activity in human B cells

Haematologica (Roma), 2017-03, Vol.102 (3), p.573-583

2017

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Aberrant Wnt signaling in multiple myeloma: molecular mechanisms and targeting options

A loss-of-adhesion CRISPR-Cas9 screening platform to identify cell adhesion-regulatory proteins and signaling pathways

The clinically active BTK inhibitor PCI-32765 targets B-cell receptor– and chemokine-controlled adhesion and migration in chronic lymphocytic leukemia

What's brewing for MALT1 in lymphoma?

Identification of the SRC-family tyrosine kinase HCK as a therapeutic target in mantle cell lymphoma

MET Signaling Overcomes Epidermal Growth Factor Receptor Inhibition in Normal and Colorectal Cancer Stem Cells Causing Drug Resistance

MYD88 mutations identify a molecular subgroup of diffuse large B-cell lymphoma with an unfavorable prognosis

Heparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myeloma

Inhibition of casein kinase 2 sensitizes mantle cell lymphoma to venetoclax through MCL-1 downregulation

Immune evasion in primary testicular and central nervous system lymphomas: HLA loss rather than 9p24.1/PD-L1/PD-L2 alterations

The forkhead transcription factor FOXP1 represses human plasma cell differentiation

Bruton's Tyrosine Kinase and Phospholipase Cγ2 Mediate Chemokine-Controlled B Cell Migration and Homing

The anaphase-promoting complex/cyclosome: a new promising target in diffuse large B-cell lymphoma and mantle cell lymphoma

Lymphoma dissemination: the other face of lymphocyte homing

The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

Deletion of the WNT target and cancer stem cell marker CD44 in Apc(Min/+) mice attenuates intestinal tumorigenesis

Ibrutinib and idelalisib target B cell receptor- but not CXCL12/CXCR4-controlled integrin-mediated adhesion in Waldenström macroglobulinemia

The oncogenic human B-cell lymphoma MYD88 L265P mutation genocopies activation by phosphorylation at the Toll/interleukin-1 receptor (TIR) domain

MALT1-dependent cleavage of CYLD promotes NF-κB signaling and growth of aggressive B-cell receptor-dependent lymphomas

Correction to: The CXCL12gamma chemokine immobilized by heparan sulfate on stromal niche cells controls adhesion and mediates drug resistance in multiple myeloma

Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies

Illegitimate WNT Signaling Promotes Proliferation of Multiple Myeloma Cells

Transcriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myeloma

The HGF/MET pathway as target for the treatment of multiple myeloma and B-cell lymphomas

The small FOXP1 isoform predominantly expressed in activated B cell-like diffuse large B-cell lymphoma and full-length FOXP1 exert similar oncogenic and transcriptional activity in human B cells

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