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Dabrafenib; preclinical characterization, increased efficacy when combined with trametinib, while BRAF/MEK tool combination reduced skin lesions

PloS one, 2013-07, Vol.8 (7), p.e67583-e67583

2013

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Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials

PloS one, 2012-04, Vol.7 (4), p.e35309-e35309

2012

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High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy

PloS one, 2012-06, Vol.7 (6), p.e38254-e38254

2012

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Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail

PloS one, 2013-07, Vol.8 (7), p.e69593-e69593

2013

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RASopathic skin eruptions during vemurafenib therapy

PloS one, 2013-03, Vol.8 (3), p.e58721

2013

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Inter- and intra-patient heterogeneity of response and progression to targeted therapy in metastatic melanoma

PloS one, 2014-01, Vol.9 (1), p.e85004-e85004

2014

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Targeting the metabolic microenvironment of tumors

Advances in pharmacology (1990), 2012, Vol.65, p.63

2012

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Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype

PloS one, 2012-07, Vol.7 (7), p.e40439

2012

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Activation of the PI3K/AKT pathway in Merkel cell carcinoma

PloS one, 2012-02, Vol.7 (2), p.e31255

2012

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Multiparametric analysis of cell-free DNA in melanoma patients

PloS one, 2012-11, Vol.7 (11), p.e49843-e49843

2012

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Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics

PloS one, 2014-07, Vol.9 (7), p.e101286-e101286

2014

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Comparison of testing methods for the detection of BRAF V600E mutations in malignant melanoma: pre-approval validation study of the companion diagnostic test for vemurafenib

PloS one, 2013-01, Vol.8 (1), p.e53733-e53733

2013

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Prenylation inhibition-induced cell death in melanoma: reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cells

PloS one, 2015-02, Vol.10 (2), p.e0117021-e0117021

2015

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A Novel SND1-BRAF Fusion Confers Resistance to c-Met Inhibitor PF-04217903 in GTL16 Cells though MAPK Activation

PloS one, 2012-06, Vol.7 (6), p.e39653

2012

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Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension

PloS one, 2012-06, Vol.7 (6), p.e38364

2012

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Simultaneous inhibition of the HGF/MET and Erk1/2 pathways affect uveal melanoma cell growth and migration

PloS one, 2014-02, Vol.9 (2), p.e83957-e83957

2014

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Intratumoral heterogeneity as a therapy resistance mechanism: role of melanoma subpopulations

Advances in pharmacology (1990), 2012, Vol.65, p.335

2012

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Ras and Rac1, frequently mutated in melanomas, are activated by superoxide anion, modulate Dnmt1 level and are causally related to melanocyte malignant transformation

PloS one, 2013-12, Vol.8 (12), p.e81937

2013

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Activity of the heat shock protein 90 inhibitor ganetespib in melanoma

PloS one, 2013-02, Vol.8 (2), p.e56134

2013

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Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression

PloS one, 2012-12, Vol.7 (12), p.e52753

2012

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TWEAK affects keratinocyte G2/M growth arrest and induces apoptosis through the translocation of the AIF protein to the nucleus

PloS one, 2012-03, Vol.7 (3), p.e33609-e33609

2012

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The role of LEF1 in endometrial gland formation and carcinogenesis

PloS one, 2012-07, Vol.7 (7), p.e40312

2012

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Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma

PloS one, 2015-09, Vol.10 (9), p.e0138210-e0138210

2015

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HSP90 inhibitors for cancer therapy and overcoming drug resistance

Advances in pharmacology (1990), 2012, Vol.65, p.471

2012

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Merlin is a negative regulator of human melanoma growth

PloS one, 2012-08, Vol.7 (8), p.e43295

2012

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Dabrafenib; preclinical characterization, increased efficacy when combined with trametinib, while BRAF/MEK tool combination reduced skin lesions

Routine multiplex mutational profiling of melanomas enables enrollment in genotype-driven therapeutic trials

High expression of Wee1 is associated with poor disease-free survival in malignant melanoma: potential for targeted therapy

Activation of Wnt/β-catenin signaling increases apoptosis in melanoma cells treated with trail

RASopathic skin eruptions during vemurafenib therapy

Inter- and intra-patient heterogeneity of response and progression to targeted therapy in metastatic melanoma

Targeting the metabolic microenvironment of tumors

Impact of combined mTOR and MEK inhibition in uveal melanoma is driven by tumor genotype

Activation of the PI3K/AKT pathway in Merkel cell carcinoma

Multiparametric analysis of cell-free DNA in melanoma patients

Clinical profiling of BCL-2 family members in the setting of BRAF inhibition offers a rationale for targeting de novo resistance using BH3 mimetics

Comparison of testing methods for the detection of BRAF V600E mutations in malignant melanoma: pre-approval validation study of the companion diagnostic test for vemurafenib

Prenylation inhibition-induced cell death in melanoma: reduced sensitivity in BRAF mutant/PTEN wild-type melanoma cells

A Novel SND1-BRAF Fusion Confers Resistance to c-Met Inhibitor PF-04217903 in GTL16 Cells though MAPK Activation

Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension

Simultaneous inhibition of the HGF/MET and Erk1/2 pathways affect uveal melanoma cell growth and migration

Intratumoral heterogeneity as a therapy resistance mechanism: role of melanoma subpopulations

Ras and Rac1, frequently mutated in melanomas, are activated by superoxide anion, modulate Dnmt1 level and are causally related to melanocyte malignant transformation

Activity of the heat shock protein 90 inhibitor ganetespib in melanoma

Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression

TWEAK affects keratinocyte G2/M growth arrest and induces apoptosis through the translocation of the AIF protein to the nucleus

The role of LEF1 in endometrial gland formation and carcinogenesis

Systems Analysis of Adaptive Responses to MAP Kinase Pathway Blockade in BRAF Mutant Melanoma

HSP90 inhibitors for cancer therapy and overcoming drug resistance

Merlin is a negative regulator of human melanoma growth

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