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Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence

Cell reports (Cambridge), 2017-12, Vol.21 (10), p.2796-2812

2017

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Fibroblast Growth Factor Receptors Are Components of Autocrine Signaling Networks in Head and Neck Squamous Cell Carcinoma Cells

Clinical cancer research, 2011-08, Vol.17 (15), p.5016-5025

2011

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An Inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases

PloS one, 2015-05, Vol.10 (5), p.e0123600-e0123600

2015

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Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

Nature genetics, 2020-04, Vol.52 (4), p.408-417

2020

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Systematic identification of signaling pathways with potential to confer anticancer drug resistance

Science signaling, 2014-12, Vol.7 (357), p.ra121

2014

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Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC

Cancer research (Chicago, Ill.), 2015-10, Vol.75 (20), p.4398-4406

2015

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Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines

Molecular pharmacology, 2019-12, Vol.96 (6), p.862-870

2019

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Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis

The Journal of biological chemistry, 2020-01, Vol.295 (1), p.111-124

2020

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Analysis of Drug Resistance Using Kinome-Wide Functional Screens

Methods in molecular biology (Clifton, N.J.), 2017, Vol.1636, p.163

2017

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A receptor tyrosine kinase network composed of fibroblast growth factor receptors, epidermal growth factor receptor, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, and hepatocyte growth factor receptor drives growth and survival of head and neck squamous carcinoma cell lines

Molecular pharmacology, 2013-04, Vol.83 (4), p.882-893

2013

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ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer

Oncotarget, 2018-02, Vol.9 (10), p.8823-8835

2018

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Drug dependence in cancer is exploitable by optimally constructed treatment holidays

Nature ecology & evolution, 2024-01, Vol.8 (1), p.147

2024

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Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy

Bioinformatics (Oxford, England), 2014-09, Vol.30 (17), p.2393-2398

2014

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Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes

Genes & cancer, 2016-07, Vol.7 (7-8), p.218-228

2016

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Elevated extracellular K + inhibits apoptosis of corneal epithelial cells exposed to UV-B radiation

Experimental eye research, 2009-08, Vol.89 (2), p.140-151

2009

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Abstract B35: Alternate receptor tyrosine kinases provide protection from FGFR inhibition in HNSCC cells as identified by genome-wide shRNA screening

Clinical cancer research, 2012-05, Vol.18 (10_Supplement), p.B35-B35

2012

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Abstract 3387: Tyrosine kinase inhibitors induce TGF-β2 expression in head and neck squamous cell carcinoma cell lines as a mechanism of acquired resistance

Cancer research (Chicago, Ill.), 2013-04, Vol.73 (8_Supplement), p.3387-3387

2013

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An Inducible TGF-[beta]2-TGF[beta]R Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases.(transforming growth factors and head and neck squamous cell carcinomas)

PloS one, 2015-05, Vol.10 (5)

2015

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Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis

The Journal of biological chemistry, 2020-01, Vol.295 (1), p.111

2020

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Abstract 5594: ALK-driven lung cancer: Potential therapeutic strategies for treatment and prevention of drug resistance

Cancer research (Chicago, Ill.), 2012-04, Vol.72 (8_Supplement), p.5594-5594

2012

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Perceived Barriers and Benefits of Exercise Among Men with Histories of Sexual Violence: Impact of PTSD and Physical Activity Status

Journal of interpersonal violence, 2023-12, Vol.38 (23-24), p.11842-11869

2023

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Effectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel

The New England journal of medicine, 2021-12, Vol.385 (25), p.e90-e90

2021

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Sex-specific associations between self-reported physical activity and PTSD among survivors of sexual violence

Journal of behavioral medicine, 2024-04, Vol.47 (2), p.220-231

2024

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Perceived Barriers and Benefits of Exercise Among Women Survivors of Sexual Violence by Physical Activity Level and Posttraumatic Stress Disorder Status

Violence against women, 2023-06, p.10778012231182412-10778012231182412

2023

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Melanoma Therapeutic Strategies that Select against Resistance by Exploiting MYC-Driven Evolutionary Convergence

Fibroblast Growth Factor Receptors Are Components of Autocrine Signaling Networks in Head and Neck Squamous Cell Carcinoma Cells

An Inducible TGF-β2-TGFβR Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases

Using antagonistic pleiotropy to design a chemotherapy-induced evolutionary trap to target drug resistance in cancer

Systematic identification of signaling pathways with potential to confer anticancer drug resistance

Kinome RNAi Screens Reveal Synergistic Targeting of MTOR and FGFR1 Pathways for Treatment of Lung Cancer and HNSCC

Functional RNAi Screens Define Distinct Protein Kinase Vulnerabilities in EGFR-Dependent HNSCC Cell Lines

Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis

Analysis of Drug Resistance Using Kinome-Wide Functional Screens

A receptor tyrosine kinase network composed of fibroblast growth factor receptors, epidermal growth factor receptor, v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, and hepatocyte growth factor receptor drives growth and survival of head and neck squamous carcinoma cell lines

ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer

Drug dependence in cancer is exploitable by optimally constructed treatment holidays

Bioinformatics-driven discovery of rational combination for overcoming EGFR-mutant lung cancer resistance to EGFR therapy

Narrowing the focus: a toolkit to systematically connect oncogenic signaling pathways with cancer phenotypes

Elevated extracellular K + inhibits apoptosis of corneal epithelial cells exposed to UV-B radiation

Abstract B35: Alternate receptor tyrosine kinases provide protection from FGFR inhibition in HNSCC cells as identified by genome-wide shRNA screening

Abstract 3387: Tyrosine kinase inhibitors induce TGF-β2 expression in head and neck squamous cell carcinoma cell lines as a mechanism of acquired resistance

An Inducible TGF-[beta]2-TGF[beta]R Pathway Modulates the Sensitivity of HNSCC Cells to Tyrosine Kinase Inhibitors Targeting Dominant Receptor Tyrosine Kinases.(transforming growth factors and head and neck squamous cell carcinomas)

Evolved resistance to partial GAPDH inhibition results in loss of the Warburg effect and in a different state of glycolysis

Abstract 5594: ALK-driven lung cancer: Potential therapeutic strategies for treatment and prevention of drug resistance

Perceived Barriers and Benefits of Exercise Among Men with Histories of Sexual Violence: Impact of PTSD and Physical Activity Status

Genome‐Wide Association Studies of Cognitive and Motor Progression in Parkinson's Disease

Effectiveness of mRNA Covid-19 Vaccine among U.S. Health Care Personnel

Sex-specific associations between self-reported physical activity and PTSD among survivors of sexual violence

Perceived Barriers and Benefits of Exercise Among Women Survivors of Sexual Violence by Physical Activity Level and Posttraumatic Stress Disorder Status

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