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Integrated metabolic spatial‐temporal model for the prediction of ammonia detoxification during liver damage and regeneration

Hepatology (Baltimore, Md.), 2014-12, Vol.60 (6), p.2040-2051

2014

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Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration

Proceedings of the National Academy of Sciences - PNAS, 2010-06, Vol.107 (23), p.10371-10376

2010

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Chlorinated paraffins in food contact materials made of rubber from the German market

Emerging Contaminants, 2023-12, Vol.9 (4), p.100255, Article 100255

2023

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Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy

Nature cell biology, 2012-08, Vol.14 (8), p.829

2012

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Risk Assessment of Food Contact Materials II

EFSA journal, 2022-05, Vol.20 (Suppl 1), p.e200408-n/a

2022

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Optimality in the zonation of ammonia detoxification in rodent liver

Archives of toxicology, 2015-11, Vol.89 (11), p.2069-2078

2015

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Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

eLife, 2016-05, Vol.5

2016

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Characterization of chemical-induced sterile inflammation in vitro: application of the model compound ketoconazole in a human hepatic co-culture system

Archives of toxicology, 2017-02, Vol.91 (2), p.799-810

2017

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Risk assessment of food contact materials

EFSA journal, 2022-12, Vol.20 (Suppl 2), p.e200920-n/a

2022

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Transcription factors ETF, E2F, and SP‐1 are involved in cytokine‐independent proliferation of murine hepatocytes

Hepatology (Baltimore, Md.), 2010-12, Vol.52 (6), p.2127-2136

2010

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Indirect co-cultivation of HepG2 with differentiated THP-1 cells induces AHR signalling and release of pro-inflammatory cytokines

Toxicology in vitro, 2020-10, Vol.68, p.104957, Article 104957

2020

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MCCP: are medium-chain chlorinated paraffins of concern for humans?

Archives of toxicology, 2020-03, Vol.94 (3), p.955-957

2020

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Migration of styrene oligomers from food contact materials: in silico prediction of possible genotoxicity

Archives of toxicology, 2022-11, Vol.96 (11), p.3013-3032

2022

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Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases

Journal of hepatology, 2016-04, Vol.64 (4), p.860-871

2016

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A Systematic Evaluation of the Use of Physiologically Based Pharmacokinetic Modeling for Cross-Species Extrapolation

Journal of pharmaceutical sciences, 2015-01, Vol.104 (1), p.191-206

2015

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Keratinocytes as depository of ammonium-inducible glutamine synthetase: age- and anatomy-dependent distribution in human and rat skin

PloS one, 2009-02, Vol.4 (2), p.e4416

2009

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Aggregated aluminium exposure: risk assessment for the general population

Archives of toxicology, 2019-12, Vol.93 (12), p.3503-3521

2019

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Chlorinated paraffins in nut-nougat and chocolate spreads from the German market

Food control, 2023-03, Vol.145, p.109385, Article 109385

2023

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Novel indirect co-culture of immortalised hepatocytes with monocyte derived macrophages is characterised by pro-inflammatory cytokine networks

Toxicology in vitro, 2021-06, Vol.73, p.105134-105134, Article 105134

2021

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Genotoxicity assessment: opportunities, challenges and perspectives for quantitative evaluations of dose–response data

Archives of toxicology, 2023-09, Vol.97 (9), p.2303-2328

2023

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Hepatic co-cultures in vitro reveal suitable to detect Nrf2-mediated oxidative stress responses on the bladder carcinogen o-anisidine

Toxicology in vitro, 2017-04, Vol.40, p.153-160

2017

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Reconstructed human skin as model for liposome–skin interaction

Journal of controlled release, 1998-11, Vol.55 (2), p.271-279

1998

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Phosphatidylcholine dimers can be easily misinterpreted as cardiolipins in complex lipid mixtures: a matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of lipids from hepatocytes

Rapid communications in mass spectrometry, 2011-09, Vol.25 (18), p.2619-2626

2011

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The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes

BMC systems biology, 2012-11, Vol.6 (1), p.147-147

2012

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Integrated metabolic spatial‐temporal model for the prediction of ammonia detoxification during liver damage and regeneration

Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration

Chlorinated paraffins in food contact materials made of rubber from the German market

Modulation of glutamine metabolism by the PI(3)K-PKB-FOXO network regulates autophagy

Risk Assessment of Food Contact Materials II

Optimality in the zonation of ammonia detoxification in rodent liver

Hedgehog signaling is a potent regulator of liver lipid metabolism and reveals a GLI-code associated with steatosis

Characterization of chemical-induced sterile inflammation in vitro: application of the model compound ketoconazole in a human hepatic co-culture system

Risk assessment of food contact materials

Transcription factors ETF, E2F, and SP‐1 are involved in cytokine‐independent proliferation of murine hepatocytes

Indirect co-cultivation of HepG2 with differentiated THP-1 cells induces AHR signalling and release of pro-inflammatory cytokines

MCCP: are medium-chain chlorinated paraffins of concern for humans?

Migration of styrene oligomers from food contact materials: in silico prediction of possible genotoxicity

Model-guided identification of a therapeutic strategy to reduce hyperammonemia in liver diseases

A Systematic Evaluation of the Use of Physiologically Based Pharmacokinetic Modeling for Cross-Species Extrapolation

Keratinocytes as depository of ammonium-inducible glutamine synthetase: age- and anatomy-dependent distribution in human and rat skin

Aggregated aluminium exposure: risk assessment for the general population

Chlorinated paraffins in nut-nougat and chocolate spreads from the German market

Novel indirect co-culture of immortalised hepatocytes with monocyte derived macrophages is characterised by pro-inflammatory cytokine networks

Genotoxicity assessment: opportunities, challenges and perspectives for quantitative evaluations of dose–response data

Hepatic co-cultures in vitro reveal suitable to detect Nrf2-mediated oxidative stress responses on the bladder carcinogen o-anisidine

Regulatory toxicology in the twenty-first century: challenges, perspectives and possible solutions

Reconstructed human skin as model for liposome–skin interaction

Phosphatidylcholine dimers can be easily misinterpreted as cardiolipins in complex lipid mixtures: a matrix-assisted laser desorption/ionization time-of-flight mass spectrometric study of lipids from hepatocytes

The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes

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