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A systematic atlas of chaperome deregulation topologies across the human cancer landscape

PLoS computational biology, 2018-01, Vol.14 (1), p.e1005890-e1005890

2018

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Two-step multi-omics modelling of drug sensitivity in cancer cell lines to identify driving mechanisms

PloS one, 2020-11, Vol.15 (11), p.e0238961-e0238961

2020

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6-month mortality and readmissions of hospitalized COVID-19 patients: A nationwide cohort study of 8,679 patients in Germany

PloS one, 2021-08, Vol.16 (8), p.e0255427-e0255427

2021

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From hype to reality: data science enabling personalized medicine

BMC medicine, 2018-08, Vol.16 (1), p.150-150, Article 150

2018

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Inflammatory processes during acute respiratory distress syndrome: a complex system

Current opinion in critical care, 2018-02, Vol.24 (1), p.1-9

2018

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Noisecut: a python package for noise-tolerant classification of binary data using prior knowledge integration and max-cut solutions

BMC bioinformatics, 2024-04, Vol.25 (1), p.155-155, Article 155

2024

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A training strategy for hybrid models to break the curse of dimensionality

PloS one, 2022-09, Vol.17 (9)

2022

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Bayesian Population Physiologically-Based Pharmacokinetic (PBPK) Approach for a Physiologically Realistic Characterization of Interindividual Variability in Clinically Relevant Populations

PloS one, 2015-10, Vol.10 (10), p.e0139423-e0139423

2015

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Few inputs can reprogram biological networks

Nature (London), 2011-10, Vol.478 (7369), p.E4; discussion E4-E4

2011

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Novel architecture for gated recurrent unit autoencoder trained on time series from electronic health records enables detection of ICU patient subgroups

Scientific reports, 2023-03, Vol.13 (1), p.4053-4053, Article 4053

2023

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A hybrid modeling framework for generalizable and interpretable predictions of ICU mortality across multiple hospitals

Scientific reports, 2024-03, Vol.14 (1), p.5725-5725, Article 5725

2024

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A training strategy for hybrid models to break the curse of dimensionality

PloS one, 2022-09, Vol.17 (9), p.e0274569-e0274569

2022

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Epigenetic and Transcriptional Shifts in Human Neural Stem Cells after Reprogramming into Induced Pluripotent Stem Cells and Subsequent Redifferentiation

International journal of molecular sciences, 2024-03, Vol.25 (6), p.3214

2024

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Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity

Nature cell biology, 2012-11, Vol.14 (11), p.1139-1147

2012

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Methodological challenges in translational drug response modeling in cancer: A systematic analysis with FORESEE

PLoS computational biology, 2020-04, Vol.16 (4), p.e1007803-e1007803

2020

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Different spreading dynamics throughout Germany during the second wave of the COVID-19 pandemic: a time series study based on national surveillance data

The Lancet regional health. Europe, 2021-07, Vol.6, p.100151-100151, Article 100151

2021

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Biometric covariates and outcome in COVID-19 patients: are we looking close enough?

BMC infectious diseases, 2021-11, Vol.21 (1), p.1-1136, Article 1136

2021

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Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage

Scientific reports, 2017-07, Vol.7 (1), p.6224-13, Article 6224

2017

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Diagnostic Expert Advisor: A platform for developing machine learning models on medical time-series data

SoftwareX, 2023-07, Vol.23, p.101517, Article 101517

2023

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Dynamische Entwicklung der COVID-19-Intensivbelegung im Herbst/Winter 2021/22 in Abhängigkeit von den 7-Tage-Inzidenzen

Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2022, Vol.117 (3), p.206-208

2022

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Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care

NPJ digital medicine, 2021-02, Vol.4 (1), p.32-12, Article 32

2021

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Dynamic simulation of COVID-19 intensive care bed occupancy in fall/winter 2021/22 as a function of 7-day incidences

Medizinische Klinik, Intensivmedizin und Notfallmedizin, 2022-04, Vol.117 (3), p.206

2022

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Analysis of Chest X-ray for COVID-19 Diagnosis as a Use Case for an HPC-Enabled Data Analysis and Machine Learning Platform for Medical Diagnosis Support

Diagnostics (Basel), 2023-01, Vol.13 (3), p.391

2023

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Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells

Stem cell reports, 2021-07, Vol.16 (7), p.1749-1762

2021

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Computational Simulation of Virtual Patients Reduces Dataset Bias and Improves Machine Learning-Based Detection of ARDS from Noisy Heterogeneous ICU Datasets

IEEE open journal of engineering in medicine and biology, 2024-01, Vol.5, p.611-620

2024

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A systematic atlas of chaperome deregulation topologies across the human cancer landscape

Two-step multi-omics modelling of drug sensitivity in cancer cell lines to identify driving mechanisms

6-month mortality and readmissions of hospitalized COVID-19 patients: A nationwide cohort study of 8,679 patients in Germany

From hype to reality: data science enabling personalized medicine

Inflammatory processes during acute respiratory distress syndrome: a complex system

Noisecut: a python package for noise-tolerant classification of binary data using prior knowledge integration and max-cut solutions

A training strategy for hybrid models to break the curse of dimensionality

Bayesian Population Physiologically-Based Pharmacokinetic (PBPK) Approach for a Physiologically Realistic Characterization of Interindividual Variability in Clinically Relevant Populations

Few inputs can reprogram biological networks

Novel architecture for gated recurrent unit autoencoder trained on time series from electronic health records enables detection of ICU patient subgroups

A hybrid modeling framework for generalizable and interpretable predictions of ICU mortality across multiple hospitals

A training strategy for hybrid models to break the curse of dimensionality

Epigenetic and Transcriptional Shifts in Human Neural Stem Cells after Reprogramming into Induced Pluripotent Stem Cells and Subsequent Redifferentiation

Nanog-dependent feedback loops regulate murine embryonic stem cell heterogeneity

Methodological challenges in translational drug response modeling in cancer: A systematic analysis with FORESEE

Different spreading dynamics throughout Germany during the second wave of the COVID-19 pandemic: a time series study based on national surveillance data

Biometric covariates and outcome in COVID-19 patients: are we looking close enough?

Physiologically-based modelling in mice suggests an aggravated loss of clearance capacity after toxic liver damage

Diagnostic Expert Advisor: A platform for developing machine learning models on medical time-series data

Dynamische Entwicklung der COVID-19-Intensivbelegung im Herbst/Winter 2021/22 in Abhängigkeit von den 7-Tage-Inzidenzen

Development and validation of a reinforcement learning algorithm to dynamically optimize mechanical ventilation in critical care

Dynamic simulation of COVID-19 intensive care bed occupancy in fall/winter 2021/22 as a function of 7-day incidences

Analysis of Chest X-ray for COVID-19 Diagnosis as a Use Case for an HPC-Enabled Data Analysis and Machine Learning Platform for Medical Diagnosis Support

Lesch-Nyhan disease causes impaired energy metabolism and reduced developmental potential in midbrain dopaminergic cells

Computational Simulation of Virtual Patients Reduces Dataset Bias and Improves Machine Learning-Based Detection of ARDS from Noisy Heterogeneous ICU Datasets

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