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Precision Oncology Medicine: The Clinical Relevance of Patient-Specific Biomarkers Used to Optimize Cancer Treatment

Journal of clinical pharmacology, 2016-12, Vol.56 (12), p.1484-1499

2016

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Resistance to second-generation androgen receptor antagonists in prostate cancer

Nature reviews. Urology, 2021-04, Vol.18 (4), p.209-226

2021

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Reviewing the role of healthy volunteer studies in drug development

Journal of translational medicine, 2018-12, Vol.16 (1), p.336-15, Article 336

2018

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Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies

Science translational medicine, 2021-01, Vol.13 (578)

2021

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Insulin potentiation therapy for cancer?

The lancet oncology, 2019-02, Vol.20 (2), p.191-192

2019

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Germline Genetics of Prostate Cancer: Prevalence of Risk Variants and Clinical Implications for Disease Management

Cancers, 2021-04, Vol.13 (9), p.2154

2021

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Antitumor Activity of NLG207 (Formerly CRLX101) in Combination with Enzalutamide in Preclinical Prostate Cancer Models

Molecular cancer therapeutics, 2021-05, Vol.20 (5), p.915-924

2021

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Combination treatment in metastatic castration-resistant prostate cancer: can we safely boost efficacy by adding radium-223?

Cancer biology & therapy, 2020-01, Vol.21 (1), p.1-3

2020

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In Silico Re‐Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure–Response Simulation

Journal of clinical pharmacology, 2023-06, Vol.63 (6), p.672-680

2023

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Examining HSD3B1 as a possible biomarker to detect prostate cancer patients who are likely to progress on ADT

Cancer biology & therapy, 2020-09, Vol.21 (9), p.782-784

2020

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A Single-arm Phase II Study Combining NLG207, a Nanoparticle Camptothecin, with Enzalutamide in Advanced Metastatic Castration-resistant Prostate Cancer Post-Enzalutamide

The oncologist (Dayton, Ohio), 2022-09, Vol.27 (9), p.718-e694

2022

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Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single‐Dose Administration Under Fasting Conditions in Prostate Cancer

The oncologist (Dayton, Ohio), 2021-09, Vol.26 (9), p.729-e1493

2021

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Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma

Journal of pharmaceutical and biomedical analysis, 2020-03, Vol.181, p.113073-113073, Article 113073

2020

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Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors

Cancer chemotherapy and pharmacology, 2020-10, Vol.86 (4), p.475-486

2020

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Expanding the use of abiraterone in prostate cancer: Is earlier always better?

Cancer biology & therapy, 2018-02, Vol.19 (2), p.97-100

2018

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A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer

Cancer chemotherapy and pharmacology, 2019-10, Vol.84 (4), p.759-770

2019

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A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug–Drug Interaction Liabilities

Pharmaceutics, 2022-09, Vol.14 (9), p.1933

2022

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The potential role of curcumin in prostate cancer: the importance of optimizing pharmacokinetics in clinical studies

Translational cancer research, 2016-11, Vol.5 (S6), p.S1107-S1110

2016

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Phase 2 Study of Seviteronel (INO-464) in Patients With Metastatic Castration-Resistant Prostate Cancer After Enzalutamide Treatment

Clinical genitourinary cancer, 2020-08, Vol.18 (4), p.258-267.e1

2020

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Pilot study of gadoxetate disodium-enhanced mri for localized and metastatic prostate cancers

Scientific reports, 2021-03, Vol.11 (1), p.5662-5662, Article 5662

2021

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Phase 1/2a study of PRL-02, a long-acting IM depot injection of abiraterone decanoate, in patients with prostate cancer including those previously treated with enzalutamide

Journal of clinical oncology, 2024-02, Vol.42 (4_suppl), p.140-140

2024

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Effect of inhaled iloprost on gas exchange in inhalation injury

Burns open : an international open access journal for burn injuries, 2017-10, Vol.1 (2), p.49-53

2017

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Anti-tumor activity of NLG207 (formerly CRLX101) in combination with enzalutamide in preclinical prostate cancer models

Molecular cancer therapeutics, 2021-02, Vol.20 (5), p.915-924

2021

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A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)

Angewandte Chemie (International ed.), 2015-04, Vol.54 (17), p.5166-5170

2015

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Precision Oncology Medicine: The Clinical Relevance of Patient-Specific Biomarkers Used to Optimize Cancer Treatment

Resistance to second-generation androgen receptor antagonists in prostate cancer

Reviewing the role of healthy volunteer studies in drug development

Whole-exome sequencing reveals germline-mutated small cell lung cancer subtype with favorable response to DNA repair-targeted therapies

Insulin potentiation therapy for cancer?

Germline Genetics of Prostate Cancer: Prevalence of Risk Variants and Clinical Implications for Disease Management

Antitumor Activity of NLG207 (Formerly CRLX101) in Combination with Enzalutamide in Preclinical Prostate Cancer Models

Combination treatment in metastatic castration-resistant prostate cancer: can we safely boost efficacy by adding radium-223?

In Silico Re‐Optimization of Atezolizumab Dosing Using Population Pharmacokinetic Simulation and Exposure–Response Simulation

Examining HSD3B1 as a possible biomarker to detect prostate cancer patients who are likely to progress on ADT

A Single-arm Phase II Study Combining NLG207, a Nanoparticle Camptothecin, with Enzalutamide in Advanced Metastatic Castration-resistant Prostate Cancer Post-Enzalutamide

Study to Compare Capsule and Liquid Formulations of Enzalutamide After Single‐Dose Administration Under Fasting Conditions in Prostate Cancer

Measurement of NLG207 (formerly CRLX101) nanoparticle-bound and released camptothecin in human plasma

Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors

Expanding the use of abiraterone in prostate cancer: Is earlier always better?

A population pharmacokinetic analysis of the oral CYP17 lyase and androgen receptor inhibitor seviteronel in patients with advanced/metastatic castration-resistant prostate cancer or breast cancer

A Metabolomics Approach for Predicting OATP1B-Type Transporter-Mediated Drug–Drug Interaction Liabilities

The potential role of curcumin in prostate cancer: the importance of optimizing pharmacokinetics in clinical studies

Phase 2 Study of Seviteronel (INO-464) in Patients With Metastatic Castration-Resistant Prostate Cancer After Enzalutamide Treatment

Pilot study of gadoxetate disodium-enhanced mri for localized and metastatic prostate cancers

Sitagliptin elevates plasma and CSF incretin levels following oral administration to nonhuman primates: relevance for neurodegenerative disorders

Phase 1/2a study of PRL-02, a long-acting IM depot injection of abiraterone decanoate, in patients with prostate cancer including those previously treated with enzalutamide

Effect of inhaled iloprost on gas exchange in inhalation injury

Anti-tumor activity of NLG207 (formerly CRLX101) in combination with enzalutamide in preclinical prostate cancer models

A Potent, Selective and Cell-Active Allosteric Inhibitor of Protein Arginine Methyltransferase 3 (PRMT3)

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