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Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemia

PloS one, 2017-10, Vol.12 (10), p.e0186426-e0186426

2017

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Matrix metalloproteinase proteolysis of the myelin basic protein isoforms is a source of immunogenic peptides in autoimmune multiple sclerosis

PloS one, 2009-03, Vol.4 (3), p.e4952-e4952

2009

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Transgenic Overexpression of Tissue-Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification

Journal of the American Heart Association, 2015-12, Vol.4 (12), p.n/a

2015

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Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes

Frontiers in endocrinology (Lausanne), 2021-11, Vol.12, p.737276-737276

2021

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Preclinical characterization of recombinant human tissue kallikrein-1 as a novel treatment for type 2 diabetes mellitus

PloS one, 2014-08, Vol.9 (8), p.e103981

2014

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Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1

PloS one, 2014-09, Vol.9 (9), p.e107213-e107213

2014

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Efficient Synthetic Inhibitors of Anthrax Lethal Factor

Proceedings of the National Academy of Sciences - PNAS, 2005-07, Vol.102 (27), p.9499-9504

2005

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Inflammatory Proprotein Convertase-Matrix Metalloproteinase Proteolytic Pathway in Antigen-presenting Cells as a Step to Autoimmune Multiple Sclerosis

The Journal of biological chemistry, 2009-10, Vol.284 (44), p.30615-30626

2009

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Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Exhibits an Important Intracellular Cleavage Function and Causes Chromosome Instability

The Journal of biological chemistry, 2005-07, Vol.280 (26), p.25079-25086

2005

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Targeting Host Cell Furin Proprotein Convertases as a Therapeutic Strategy against Bacterial Toxins and Viral Pathogens

The Journal of biological chemistry, 2007-07, Vol.282 (29), p.20847-20853

2007

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O-Glycosylation Regulates Autolysis of Cellular Membrane Type-1 Matrix Metalloproteinase (MT1-MMP)

The Journal of biological chemistry, 2006-06, Vol.281 (25), p.16897-16905

2006

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Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor

Cellular immunology, 2020-12, Vol.358, p.104224-104224, Article 104224

2020

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Contribution of Fas to Diabetes Development

Proceedings of the National Academy of Sciences - PNAS, 2003-01, Vol.100 (2), p.628-632

2003

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Engineering a leucine zipper-TRAIL homotrimer with improved cytotoxicity in tumor cells

Molecular cancer therapeutics, 2009-06, Vol.8 (6), p.1515-1525

2009

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Human beta-cell precursors mature into functional insulin-producing cells in an immunoisolation device: implications for diabetes cell therapies

Transplantation, 2009-04, Vol.87 (7), p.983

2009

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Self-Transducible Bimodal PDX1-FOXP3 Protein Lifts Insulin Secretion and Curbs Autoimmunity, Boosting Tregs in Type 1 Diabetic Mice

Molecular therapy, 2018-01, Vol.26 (1), p.184-198

2018

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Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes

The Journal of immunology (1950), 2016-02, Vol.196 (4), p.1495-1506

2016

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Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development

Diabetes (New York, N.Y.), 2014-10, Vol.63 (10), p.3470-3482

2014

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Inhibition of Membrane Type-1 Matrix Metalloproteinase by Cancer Drugs Interferes with the Homing of Diabetogenic T Cells into the Pancreas

The Journal of biological chemistry, 2005-07, Vol.280 (30), p.27755-27758

2005

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Cellular Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Cleaves C3b, an Essential Component of the Complement System

The Journal of biological chemistry, 2004-11, Vol.279 (45), p.46551-46557

2004

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Interference with islet-specific homing of autoreactive T cells: an emerging therapeutic strategy for type 1 diabetes

Drug discovery today, 2010-07, Vol.15 (13), p.531-539

2010

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Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells

The Journal of experimental medicine, 2003-03, Vol.197 (5), p.643-656

2003

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Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer

Cancer research (Chicago, Ill.), 2008-06, Vol.68 (11), p.4086-4096

2008

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Matrix metalloproteinase 26 proteolysis of the NH2-terminal domain of the estrogen receptor β correlates with the survival of breast cancer patients

Cancer research (Chicago, Ill.), 2006-03, Vol.66 (5), p.2716-2724

2006

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Matrix Metalloproteinases, T Cell Homing and beta-Cell Mass in Type 1 Diabetes

Insulin and IGFs, 2009, Vol.80, p.541

Litwack, Gerald

2009

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Overexpression of tissue-nonspecific alkaline phosphatase (TNAP) in endothelial cells accelerates coronary artery disease in a mouse model of familial hypercholesterolemia

Matrix metalloproteinase proteolysis of the myelin basic protein isoforms is a source of immunogenic peptides in autoimmune multiple sclerosis

Transgenic Overexpression of Tissue-Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification

Use of Induced Pluripotent Stem Cells to Build Isogenic Systems and Investigate Type 1 Diabetes

Preclinical characterization of recombinant human tissue kallikrein-1 as a novel treatment for type 2 diabetes mellitus

Autoimmune diabetes is suppressed by treatment with recombinant human tissue Kallikrein-1

Efficient Synthetic Inhibitors of Anthrax Lethal Factor

Inflammatory Proprotein Convertase-Matrix Metalloproteinase Proteolytic Pathway in Antigen-presenting Cells as a Step to Autoimmune Multiple Sclerosis

Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Exhibits an Important Intracellular Cleavage Function and Causes Chromosome Instability

Targeting Host Cell Furin Proprotein Convertases as a Therapeutic Strategy against Bacterial Toxins and Viral Pathogens

O-Glycosylation Regulates Autolysis of Cellular Membrane Type-1 Matrix Metalloproteinase (MT1-MMP)

Towards antigen-specific Tregs for type 1 diabetes: Construction and functional assessment of pancreatic endocrine marker, HPi2-based chimeric antigen receptor

Contribution of Fas to Diabetes Development

Engineering a leucine zipper-TRAIL homotrimer with improved cytotoxicity in tumor cells

Human beta-cell precursors mature into functional insulin-producing cells in an immunoisolation device: implications for diabetes cell therapies

Self-Transducible Bimodal PDX1-FOXP3 Protein Lifts Insulin Secretion and Curbs Autoimmunity, Boosting Tregs in Type 1 Diabetic Mice

Loss of Peripheral Protection in Pancreatic Islets by Proteolysis-Driven Impairment of VTCN1 (B7-H4) Presentation Is Associated with the Development of Autoimmune Diabetes

Nardilysin-dependent proteolysis of cell-associated VTCN1 (B7-H4) marks type 1 diabetes development

Inhibition of Membrane Type-1 Matrix Metalloproteinase by Cancer Drugs Interferes with the Homing of Diabetogenic T Cells into the Pancreas

Cellular Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) Cleaves C3b, an Essential Component of the Complement System

Interference with islet-specific homing of autoreactive T cells: an emerging therapeutic strategy for type 1 diabetes

Presentation of antigen by endothelial cells and chemoattraction are required for homing of insulin-specific CD8+ T cells

Molecular signature of MT1-MMP: transactivation of the downstream universal gene network in cancer

Matrix metalloproteinase 26 proteolysis of the NH2-terminal domain of the estrogen receptor β correlates with the survival of breast cancer patients

Matrix Metalloproteinases, T Cell Homing and beta-Cell Mass in Type 1 Diabetes

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