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Epigenetic Regulation of Nutrient Transporters in Rheumatoid Arthritis Fibroblast‐like Synoviocytes

Arthritis & rheumatology (Hoboken, N.J.), 2022-07, Vol.74 (7), p.1159-1171

2022

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Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling

Immunity (Cambridge, Mass.), 2022-08, Vol.55 (8), p.1370-1385.e8

2022

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New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

Nature (London), 2018-08, Vol.560 (7717), p.198-203

2018

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Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

Immunity (Cambridge, Mass.), 2021-07, Vol.54 (7), p.1463-1477.e11

2021

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Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis

Frontiers in immunology, 2019-08, Vol.10, p.1743-1743

2019

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Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis

Immunity (Cambridge, Mass.), 2014-12, Vol.41 (6), p.1052-1063

2014

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Can Metabolic Pathways Be Therapeutic Targets in Rheumatoid Arthritis?

Journal of clinical medicine, 2019-05, Vol.8 (5), p.753

2019

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Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response

Cell reports (Cambridge), 2022-03, Vol.38 (10), p.110489-110489, Article 110489

2022

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Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes

Frontiers in immunology, 2023-07, Vol.14, p.1103231

2023

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Angiotensin II, via angiotensin receptor type 1/nuclear factor-κB activation, causes a synergistic effect on interleukin-1-β-induced inflammatory responses in cultured mesangial cells

Journal of the renin-angiotensin-aldosterone system, 2015-03, Vol.16 (1), p.23-32

2015

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Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation

Clinical science (1979), 2014-07, Vol.127 (1), p.19-31

2014

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HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated by high glucose and angiotensin II

Laboratory investigation, 2012-01, Vol.92 (1), p.32-45

2012

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Autophagy, NLRP3 inflammasome and auto-inflammatory/immune diseases

Clinical and experimental rheumatology, 2016-07, Vol.34 (4 Suppl 98), p.12

2016

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Endothelin-1, via ETA Receptor and Independently of Transforming Growth Factor-β, Increases the Connective Tissue Growth Factor in Vascular Smooth Muscle Cells

Circulation research, 2005-07, Vol.97 (2), p.125-134

2005

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Angiotensin II activates the smad pathway in vascular smooth muscle cells by a transforming growth factor-β-independent mechanism

Circulation (New York, N.Y.), 2005-05, Vol.111 (19), p.2509-2517

2005

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Synovial inflammation in osteoarthritis progression

Nature reviews. Rheumatology, 2022-05, Vol.18 (5), p.258-275

2022

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NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

Cell, 2016-02, Vol.164 (5), p.896-910

2016

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Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

Nature (London), 2015-05, Vol.521 (7550), p.94-98

2015

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Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production

Cell metabolism, 2019-06, Vol.29 (6), p.1350-1362.e7

2019

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Differential effect of quercetin on cisplatin-induced toxicity in kidney and tumor tissues

Food and chemical toxicology, 2017-09, Vol.107 (Pt A), p.226-236

2017

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Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis

Annals of the rheumatic diseases, 2018-11, Vol.77 (11), p.1636-1643

2018

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Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases

Nephrology, dialysis, transplantation, 2006-01, Vol.21 (1), p.16-20

2006

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Hypoxia-Inducible Factor-1α: The Master Regulator of Endothelial Cell Senescence in Vascular Aging

Cells (Basel, Switzerland), 2020-01, Vol.9 (1), p.195

2020

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TGF-beta signaling in vascular fibrosis

Cardiovascular research, 2007-05, Vol.74 (2), p.196-206

2007

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Epigenetic Regulation of Nutrient Transporters in Rheumatoid Arthritis Fibroblast‐like Synoviocytes

Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling

New mitochondrial DNA synthesis enables NLRP3 inflammasome activation

Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation

Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis

Interleukin-17 Receptor A Signaling in Transformed Enterocytes Promotes Early Colorectal Tumorigenesis

Can Metabolic Pathways Be Therapeutic Targets in Rheumatoid Arthritis?

Monosodium urate crystals regulate a unique JNK-dependent macrophage metabolic and inflammatory response

Role of mitochondria-bound HK2 in rheumatoid arthritis fibroblast-like synoviocytes

Angiotensin II, via angiotensin receptor type 1/nuclear factor-κB activation, causes a synergistic effect on interleukin-1-β-induced inflammatory responses in cultured mesangial cells

Autophagy-mitophagy induction attenuates cardiovascular inflammation in a murine model of Kawasaki disease vasculitis

Integrin-linked kinase plays a key role in the regulation of angiotensin II-induced renal inflammation

HSP27/HSPB1 as an adaptive podocyte antiapoptotic protein activated by high glucose and angiotensin II

Autophagy, NLRP3 inflammasome and auto-inflammatory/immune diseases

Endothelin-1, via ETA Receptor and Independently of Transforming Growth Factor-β, Increases the Connective Tissue Growth Factor in Vascular Smooth Muscle Cells

Angiotensin II activates the smad pathway in vascular smooth muscle cells by a transforming growth factor-β-independent mechanism

Synovial inflammation in osteoarthritis progression

NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria

Immunosuppressive plasma cells impede T-cell-dependent immunogenic chemotherapy

Choline Uptake and Metabolism Modulate Macrophage IL-1β and IL-18 Production

Differential effect of quercetin on cisplatin-induced toxicity in kidney and tumor tissues

Hexokinase 2 as a novel selective metabolic target for rheumatoid arthritis

Angiotensin II: a key factor in the inflammatory and fibrotic response in kidney diseases

Hypoxia-Inducible Factor-1α: The Master Regulator of Endothelial Cell Senescence in Vascular Aging

TGF-beta signaling in vascular fibrosis

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