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Mitochondrial Uncoupling and the Warburg Effect: Molecular Basis for the Reprogramming of Cancer Cell Metabolism

Cancer research (Chicago, Ill.), 2009-03, Vol.69 (6), p.2163-2166

2009

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Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

Blood, 2009-06, Vol.113 (24), p.6215-6224

2009

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Cell-surface proteomics for the identification of novel therapeutic targets in cancer

Expert review of proteomics, 2018-03, Vol.15 (3), p.259-275

2018

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Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

The Journal of clinical investigation, 2010-01, Vol.120 (1), p.142-156

2010

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Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML

Blood, 2007-04, Vol.109 (8), p.3509-3512

2007

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MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

Blood, 2005-11, Vol.106 (9), p.3150-3159

2005

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Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias

Molecular cancer therapeutics, 2006-12, Vol.5 (12), p.3113-3121

2006

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Effects of natural antioxidants in neurodegenerative disease

Nutritional neuroscience, 2012-01, Vol.15 (1), p.1-9

2012

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DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis

PloS one, 2016-03, Vol.11 (3), p.e0152538

2016

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3,3′-Diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5

Carcinogenesis (New York), 2006-04, Vol.27 (4), p.717-728

2006

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CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure

Blood, 2009-02, Vol.113 (7), p.1504-1512

2009

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Pre-Existing HSV-1 Immunity Enhances Anticancer Efficacy of a Novel Immune-Stimulating Oncolytic Virus

Viruses, 2022-10, Vol.14 (11), p.2327

2022

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Oncolytic virotherapy in hepato‐bilio‐pancreatic cancer: The key to breaking the log jam?

Cancer medicine (Malden, MA), 2020-05, Vol.9 (9), p.2943-2959

2020

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Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

Cancer biology & therapy, 2012-08, Vol.13 (10), p.858-870

2012

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Concomitant Inhibition of MDM2 and Bcl-2 Protein Function Synergistically Induce Mitochondrial Apoptosis in AML

Cell cycle (Georgetown, Tex.), 2006-12, Vol.5 (23), p.2778-2786

2006

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UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells

Blood, 2016-05, Vol.127 (21), p.2575-2586

2016

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Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells

Cancer research (Chicago, Ill.), 2007-04, Vol.67 (7), p.3210-3219

2007

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Estrogen Regulation of Cyclin D1 Gene Expression in ZR-75 Breast Cancer Cells Involves Multiple Enhancer Elements

The Journal of biological chemistry, 2001-08, Vol.276 (33), p.30853-30861

2001

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Simultaneous inhibition of PDK1/AKT and fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia

Cancer research (Chicago, Ill.), 2006-04, Vol.66 (7), p.3737-3746

2006

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A novel ring-substituted diindolylmethane, 1,1-bis[3'-(5-Methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia

Cancer research (Chicago, Ill.), 2005-04, Vol.65 (7), p.2890-2898

2005

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Targeting leukemia's “fatty tooth”

Blood, 2015-10, Vol.126 (16), p.1874-1875

2015

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Small Inhibitory RNA Duplexes for Sp1 mRNA Block Basal and Estrogen-induced Gene Expression and Cell Cycle Progression in MCF-7 Breast Cancer Cells

The Journal of biological chemistry, 2002-08, Vol.277 (32), p.28815-28822

2002

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2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) Directly Targets Mitochondrial Glutathione to Induce Apoptosis in Pancreatic Cancer

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.36273-36282

2005

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Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells

Journal of mammary gland biology and neoplasia, 2000-07, Vol.5 (3), p.295

2000

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Mitochondrial Uncoupling and the Warburg Effect: Molecular Basis for the Reprogramming of Cancer Cell Metabolism

Targeting the leukemia microenvironment by CXCR4 inhibition overcomes resistance to kinase inhibitors and chemotherapy in AML

Cell-surface proteomics for the identification of novel therapeutic targets in cancer

Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction

Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

Inhibition of CXCR4 with the novel RCP168 peptide overcomes stroma-mediated chemoresistance in chronic and acute leukemias

Effects of natural antioxidants in neurodegenerative disease

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

DMSO Represses Inflammatory Cytokine Production from Human Blood Cells and Reduces Autoimmune Arthritis

3,3′-Diindolylmethane (DIM) and its derivatives induce apoptosis in pancreatic cancer cells through endoplasmic reticulum stress-dependent upregulation of DR5

CXCR4 expression and biologic activity in acute myeloid leukemia are dependent on oxygen partial pressure

Pre-Existing HSV-1 Immunity Enhances Anticancer Efficacy of a Novel Immune-Stimulating Oncolytic Virus

Oncolytic virotherapy in hepato‐bilio‐pancreatic cancer: The key to breaking the log jam?

Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

Concomitant Inhibition of MDM2 and Bcl-2 Protein Function Synergistically Induce Mitochondrial Apoptosis in AML

UV-inactivated HSV-1 potently activates NK cell killing of leukemic cells

Mitogen-activated protein kinase kinase inhibition enhances nuclear proapoptotic function of p53 in acute myelogenous leukemia cells

Estrogen Regulation of Cyclin D1 Gene Expression in ZR-75 Breast Cancer Cells Involves Multiple Enhancer Elements

Simultaneous inhibition of PDK1/AKT and fms-like tyrosine kinase 3 signaling by a small-molecule KP372-1 induces mitochondrial dysfunction and apoptosis in acute myelogenous leukemia

A novel ring-substituted diindolylmethane, 1,1-bis[3'-(5-Methoxyindolyl)]-1-(p-t-butylphenyl) methane, inhibits extracellular signal-regulated kinase activation and induces apoptosis in acute myelogenous leukemia

Targeting leukemia's “fatty tooth”

Small Inhibitory RNA Duplexes for Sp1 mRNA Block Basal and Estrogen-induced Gene Expression and Cell Cycle Progression in MCF-7 Breast Cancer Cells

2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) Directly Targets Mitochondrial Glutathione to Induce Apoptosis in Pancreatic Cancer

Mechanisms of inhibitory aryl hydrocarbon receptor-estrogen receptor crosstalk in human breast cancer cells

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