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Single‐cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3‐ITD‐mutated AML stem/progenitor cells

Cytometry. Part A, 2015-04, Vol.87 (4), p.346-356

2015

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Mutant FLT3: A Direct Target of Sorafenib in Acute Myelogenous Leukemia

JNCI : Journal of the National Cancer Institute, 2008-02, Vol.100 (3), p.184-198

2008

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Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia

Blood, 2006-08, Vol.108 (3), p.993-1000

2006

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The “burnt-out” testicular (Azzopardi) tumor

Abdominal radiology (New York), 2019-02, Vol.44 (2), p.800-801

2019

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Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

Haematologica (Roma), 2018-05, Vol.103 (5), p.810-821

2018

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MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

Blood, 2005-11, Vol.106 (9), p.3150-3159

2005

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A “hanging” bladder stone

Abdominal radiology (New York), 2017-12, Vol.42 (12), p.2959-2961

2017

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Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

Cancer biology & therapy, 2012-08, Vol.13 (10), p.858-870

2012

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Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells

Cancer research (Chicago, Ill.), 2007-01, Vol.67 (2), p.684-694

2007

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Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells

Blood, 2006-07, Vol.108 (2), p.630-637

2006

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Blockade of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase and Murine Double Minute Synergistically Induces Apoptosis in Acute Myeloid Leukemia via BH3-Only Proteins Puma and Bim

Cancer research (Chicago, Ill.), 2010-03, Vol.70 (6), p.2424-2434

2010

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Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs

PloS one, 2015-09, Vol.10 (9), p.e0138377

2015

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The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia

Cancer research (Chicago, Ill.), 2004-11, Vol.64 (21), p.7927-7935

2004

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Role of Mesenchymal Stem Cell Galectin 3 in the AML Tumor Microenvironment

Blood, 2015-12, Vol.126 (23), p.1198-1198

2015

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2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) Directly Targets Mitochondrial Glutathione to Induce Apoptosis in Pancreatic Cancer

The Journal of biological chemistry, 2005-10, Vol.280 (43), p.36273-36282

2005

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Peroxisome proliferator-activated receptor γ and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias

Molecular cancer therapeutics, 2004-10, Vol.3 (10), p.1249-1262

2004

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PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment

Journal of molecular medicine (Berlin, Germany), 2013-12, Vol.91 (12), p.1383-1397

2013

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Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure

Molecular cancer therapeutics, 2005-12, Vol.4 (12), p.1982-1992

2005

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Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells

Molecular cancer therapeutics, 2006-02, Vol.5 (2), p.317-328

2006

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Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma

PloS one, 2007-06, Vol.2 (6), p.e559-e559

2007

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Hypoxia Activated Pro-Drug TH-302 Induces Hypoxia-Dependent Anti-leukemia Activity in vitro and in vivo

Clinical lymphoma, myeloma and leukemia, 2013-09, Vol.13, p.S377-S377

2013

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Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia

Blood, 2016-09, Vol.128 (9), p.1260-1269

2016

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BETP degradation simultaneously targets acute myelogenous leukemic stem cells and the microenvironment

The Journal of clinical investigation, 2019-05, Vol.129 (5), p.1878-1894

2019

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Single‐cell mass cytometry reveals intracellular survival/proliferative signaling in FLT3‐ITD‐mutated AML stem/progenitor cells

Mutant FLT3: A Direct Target of Sorafenib in Acute Myelogenous Leukemia

Mdm2 inhibitor Nutlin-3a induces p53-mediated apoptosis by transcription-dependent and transcription-independent mechanisms and may overcome Atm-mediated resistance to fludarabine in chronic lymphocytic leukemia

Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia

The “burnt-out” testicular (Azzopardi) tumor

Distinct protein signatures of acute myeloid leukemia bone marrow-derived stromal cells are prognostic for patient survival

MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy

A “hanging” bladder stone

Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment

Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells

Triptolide induces caspase-dependent cell death mediated via the mitochondrial pathway in leukemic cells

AML-induced osteogenic differentiation in mesenchymal stromal cells supports leukemia growth

Blockade of Mitogen-Activated Protein Kinase/Extracellular Signal-Regulated Kinase Kinase and Murine Double Minute Synergistically Induces Apoptosis in Acute Myeloid Leukemia via BH3-Only Proteins Puma and Bim

Mitochondrial Profiling of Acute Myeloid Leukemia in the Assessment of Response to Apoptosis Modulating Drugs

The synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces caspase-dependent and -independent apoptosis in acute myelogenous leukemia

Role of Mesenchymal Stem Cell Galectin 3 in the AML Tumor Microenvironment

2-Cyano-3,12-dioxooleana-1,9-dien-28-imidazolide (CDDO-Im) Directly Targets Mitochondrial Glutathione to Induce Apoptosis in Pancreatic Cancer

Peroxisome proliferator-activated receptor γ and retinoid X receptor ligands are potent inducers of differentiation and apoptosis in leukemias

PI3K inhibitor GDC-0941 enhances apoptotic effects of BH-3 mimetic ABT-737 in AML cells in the hypoxic bone marrow microenvironment

Guggulsterones induce apoptosis and differentiation in acute myeloid leukemia: identification of isomer-specific antileukemic activities of the pregnadienedione structure

Synthetic triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid induces growth arrest in HER2-overexpressing breast cancer cells

Triterpenoids display single agent anti-tumor activity in a transgenic mouse model of chronic lymphocytic leukemia and small B cell lymphoma

Hypoxia Activated Pro-Drug TH-302 Induces Hypoxia-Dependent Anti-leukemia Activity in vitro and in vivo

Atg7 suppression enhances chemotherapeutic agent sensitivity and overcomes stroma-mediated chemoresistance in acute myeloid leukemia

BETP degradation simultaneously targets acute myelogenous leukemic stem cells and the microenvironment

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