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Sphingosine‐1‐phosphate antibodies as potential agents in the treatment of cancer and age‐related macular degeneration

British journal of pharmacology, 2011-03, Vol.162 (6), p.1225-1238

Sabbadini, Roger A.

2011

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Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway

The Journal of cell biology, 2011-05, Vol.193 (4), p.667-676

2011

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Autophagy in Oncogenic K-Ras Promotes Basal Extrusion of Epithelial Cells by Degrading S1P

Current biology, 2014-01, Vol.24 (1), p.19-28

2014

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Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer

Oncotarget, 2015-05, Vol.6 (15), p.13803-13821

2015

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Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer

Clinical cancer research, 2015-04, Vol.21 (8), p.1925-1934

2015

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Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes

Journal of neuroinflammation, 2014-02, Vol.11 (1), p.37-37

2014

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Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages

Cancer cell, 2006-03, Vol.9 (3), p.225-238

2006

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Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-β-stimulated collagen production by cardiac fibroblasts

Cardiovascular research, 2009-05, Vol.82 (2), p.303-312

2009

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Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase

PloS one, 2011-01, Vol.6 (1), p.e16571-e16571

2011

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Blockage of Lysophosphatidic Acid Signaling Improves Spinal Cord Injury Outcomes

The American journal of pathology, 2012-09, Vol.181 (3), p.978-992

2012

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Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism

PloS one, 2013-01, Vol.8 (1), p.e55255

2013

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Nervous system delivery of antilysophosphatidic acid antibody by nasal application attenuates mechanical allodynia after traumatic brain injury in rats

Pain (Amsterdam), 2017-11, Vol.158 (11), p.2181-2188

2017

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Biological Effects of Lysophosphatidic Acid in the Nervous System

International Review of Cell and Molecular Biology, 2012, Vol.296, p.273-322

2012

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Matrix-Assisted Laser Desorption Ionization Mapping of Lysophosphatidic Acid Changes after Traumatic Brain Injury and the Relationship to Cellular Pathology

The American journal of pathology, 2018-08, Vol.188 (8), p.1779-1793

2018

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Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells

Molecular oncology, 2014-10, Vol.8 (7), p.1181-1195

2014

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The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell–dependent acute allergic responses

Journal of allergy and clinical immunology, 2015-04, Vol.135 (4), p.1008-1018.e1

2015

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Acid ceramidase confers radioresistance to glioblastoma cells

Oncology reports, 2017-10, Vol.38 (4), p.1932-1940

2017

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Antibodies Against Lysophosphatidic Acid Protect Against Blast-Induced Ocular Injuries

Frontiers in neurology, 2020-12, Vol.11, p.611816-611816

2020

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Oxidized LDL‐induced angiogenesis involves sphingosine 1‐phosphate: prevention by anti‐S1P antibody

British journal of pharmacology, 2015-01, Vol.172 (1), p.106-118

2015

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Sphingosine 1-phosphate signaling through its receptor S1P 5 promotes chromosome segregation and mitotic progression

Science signaling, 2017-03, Vol.10 (472)

2017

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Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies

Journal of lipid research, 2009-11, Vol.50 (11), p.2245-2257

2009

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Defects of High-Density Lipoproteins in Coronary Artery Disease Caused by Low Sphingosine-1-Phosphate Content

Journal of the American College of Cardiology, 2015-09, Vol.66 (13), p.1470-1485

2015

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Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling

Neuron (Cambridge, Mass.), 2016-10, Vol.92 (1), p.126-142

2016

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Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization

Experimental eye research, 2009-03, Vol.88 (3), p.367-377

2009

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Sphingosine-1-phosphate (S1P) is a novel fibrotic mediator in the eye

Experimental eye research, 2008-10, Vol.87 (4), p.367-375

2008

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Sphingosine‐1‐phosphate antibodies as potential agents in the treatment of cancer and age‐related macular degeneration

Epithelial cell extrusion requires the sphingosine-1-phosphate receptor 2 pathway

Autophagy in Oncogenic K-Ras Promotes Basal Extrusion of Epithelial Cells by Degrading S1P

Neutralizing S1P inhibits intratumoral hypoxia, induces vascular remodelling and sensitizes to chemotherapy in prostate cancer

Anti-S1P Antibody as a Novel Therapeutic Strategy for VEGFR TKI-Resistant Renal Cancer

Anti-lysophosphatidic acid antibodies improve traumatic brain injury outcomes

Validation of an anti-sphingosine-1-phosphate antibody as a potential therapeutic in reducing growth, invasion, and angiogenesis in multiple tumor lineages

Sphingosine-1-phosphate and sphingosine kinase are critical for transforming growth factor-β-stimulated collagen production by cardiac fibroblasts

Intracellular S1P generation is essential for S1P-induced motility of human lung endothelial cells: role of sphingosine kinase 1 and S1P lyase

Blockage of Lysophosphatidic Acid Signaling Improves Spinal Cord Injury Outcomes

Sphingosine 1-phosphate mediates hyperalgesia via a neutrophil-dependent mechanism

Nervous system delivery of antilysophosphatidic acid antibody by nasal application attenuates mechanical allodynia after traumatic brain injury in rats

Biological Effects of Lysophosphatidic Acid in the Nervous System

Matrix-Assisted Laser Desorption Ionization Mapping of Lysophosphatidic Acid Changes after Traumatic Brain Injury and the Relationship to Cellular Pathology

Osteoblast-derived sphingosine 1-phosphate to induce proliferation and confer resistance to therapeutics to bone metastasis-derived prostate cancer cells

The sphingosine-1-phosphate/sphingosine-1-phosphate receptor 2 axis regulates early airway T-cell infiltration in murine mast cell–dependent acute allergic responses

Acid ceramidase confers radioresistance to glioblastoma cells

Antibodies Against Lysophosphatidic Acid Protect Against Blast-Induced Ocular Injuries

Oxidized LDL‐induced angiogenesis involves sphingosine 1‐phosphate: prevention by anti‐S1P antibody

Sphingosine 1-phosphate signaling through its receptor S1P 5 promotes chromosome segregation and mitotic progression

Production and characterization of monoclonal anti-sphingosine-1-phosphate antibodies

Defects of High-Density Lipoproteins in Coronary Artery Disease Caused by Low Sphingosine-1-Phosphate Content

Precise Somatotopic Thalamocortical Axon Guidance Depends on LPA-Mediated PRG-2/Radixin Signaling

Anti-sphingosine-1-phosphate monoclonal antibodies inhibit angiogenesis and sub-retinal fibrosis in a murine model of laser-induced choroidal neovascularization

Sphingosine-1-phosphate (S1P) is a novel fibrotic mediator in the eye

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