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Solubility in Pharmaceutical Chemistry

1, 2020

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Optimizing solubility: Kinetic versus thermodynamic solubility temptations and risks

European journal of pharmaceutical sciences, 2012-10, Vol.47 (3), p.589-595

2012

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Trends in Active Pharmaceutical Ingredient Salt Selection based on Analysis of the Orange Book Database

Journal of medicinal chemistry, 2007-12, Vol.50 (26), p.6665-6672

2007

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Approaches to increase mechanistic understanding and aid in the selection of precipitation inhibitors for supersaturating formulations – a PEARRL review

Journal of pharmacy and pharmacology, 2019-04, Vol.71 (4), p.483-509

2019

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Detection of trace crystallinity in an amorphous system using Raman microscopy and chemometric analysis

European journal of pharmaceutical sciences, 2011-01, Vol.42 (1), p.45-54

2011

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Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies

Pharmaceutics, 2019-11, Vol.11 (11), p.577

2019

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Selection of solid-state forms: challenges, opportunities, lessons learned and adventures from recent years

Journal of pharmacy and pharmacology, 2015-06, Vol.67 (6), p.755-756

Saal, Christoph

2015

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Selection of solid state forms for new chemical entities: challenges, opportunities and lessons

Acta crystallographica. Section A, Foundations and advances, 2016-08, Vol.72 (a1), p.s118-s118

Saal, Christoph

2016

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N-Nitrosamines Impurities in Pharmaceuticals The Abrupt Challenges that Resulted, the Evolving Science, and the Regulatory Framework

Journal of pharmaceutical sciences, 2023-05, Vol.112 (5), p.1161-1162

2023

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Atropisomerism – A Neglected Way to Escape Out of Solubility Flatlands

Journal of pharmaceutical sciences, 2022-01, Vol.111 (1), p.206-213

2022

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N-Nitrosamines Impurities in Pharmaceuticals the Abrupt Challenges They Bring and Approaches to Tackle the Risk

Journal of pharmaceutical sciences, 2022-10, Vol.111 (10), p.2651-2651

2022

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Miniaturized screening and performance prediction of tailored subcutaneous extended-release formulations for preclinical in vivo studies

European journal of pharmaceutical sciences, 2024-05, Vol.196, p.106733-106733, Article 106733

2024

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A comparison of USP 2 and µDISS Profiler™ apparatus for studying dissolution phenomena of ibuprofen and its salts

European journal of pharmaceutical sciences, 2024-02, Vol.193, p.106684-106684, Article 106684

2024

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Rational Selection of Bio-Enabling Oral Drug Formulations – A PEARRL Commentary

Journal of pharmaceutical sciences, 2021-05, Vol.110 (5), p.1921-1930

2021

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Calculation of drug-polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating pharmaceutical formulations

European journal of pharmaceutical sciences, 2019-04, Vol.132, p.142-156

2019

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Jennifer Dressman - 40 years of Oral Drug Absorption

Journal of pharmaceutical sciences, 2022-01, Vol.111 (1), p.14-17

2022

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The Landscape of Potential Small and Drug Substance Related Nitrosamines in Pharmaceuticals

Journal of pharmaceutical sciences, 2023-05, Vol.112 (5), p.1287-1304

2023

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Avoiding N-nitrosodimethylamine formation in metformin pharmaceuticals by limiting dimethylamine and nitrite

International journal of pharmaceutics, 2022-05, Vol.620, p.121740-121740, Article 121740

2022

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Industrial Pharmaceutics

European journal of pharmaceutical sciences, 2016-05, Vol.87, p.1-2

2016

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Lipophilicity and hydrophobicity considerations in bio‐enabling oral formulations approaches – a PEARRL review

Journal of pharmacy and pharmacology, 2019-04, Vol.71 (4), p.464-482

2019

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Comparison of Nephelometric, UV-Spectroscopic, and HPLC Methods for High-Throughput Determination of Aqueous Drug Solubility in Microtiter Plates

Analytical chemistry (Washington), 2009-04, Vol.81 (8), p.3165-3172

2009

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Incorporation of HPMCAS during loading of glibenclamide onto mesoporous silica improves dissolution and inhibits precipitation

European journal of pharmaceutical sciences, 2020-01, Vol.141, p.105113, Article 105113

2020

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Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Isavuconazonium Sulfate

Journal of pharmaceutical sciences, 2024-02, Vol.113 (2), p.386-395

2024

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NDMA analytics in metformin products: Comparison of methods and pitfalls

European journal of pharmaceutical sciences, 2022-01, Vol.168, p.106026-106026, Article 106026

2022

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Absolute Configuration of Pharmaceutical Research Compounds Determined by X‐ray Powder Diffraction

Angewandte Chemie (International ed.), 2018-07, Vol.57 (29), p.9150-9153

International ed. in English, 2018

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Solubility in Pharmaceutical Chemistry

Optimizing solubility: Kinetic versus thermodynamic solubility temptations and risks

Trends in Active Pharmaceutical Ingredient Salt Selection based on Analysis of the Orange Book Database

Approaches to increase mechanistic understanding and aid in the selection of precipitation inhibitors for supersaturating formulations – a PEARRL review

Detection of trace crystallinity in an amorphous system using Raman microscopy and chemometric analysis

Opportunities for Successful Stabilization of Poor Glass-Forming Drugs: A Stability-Based Comparison of Mesoporous Silica Versus Hot Melt Extrusion Technologies

Selection of solid-state forms: challenges, opportunities, lessons learned and adventures from recent years

Selection of solid state forms for new chemical entities: challenges, opportunities and lessons

N-Nitrosamines Impurities in Pharmaceuticals The Abrupt Challenges that Resulted, the Evolving Science, and the Regulatory Framework

Atropisomerism – A Neglected Way to Escape Out of Solubility Flatlands

N-Nitrosamines Impurities in Pharmaceuticals the Abrupt Challenges They Bring and Approaches to Tackle the Risk

Miniaturized screening and performance prediction of tailored subcutaneous extended-release formulations for preclinical in vivo studies

A comparison of USP 2 and µDISS Profiler™ apparatus for studying dissolution phenomena of ibuprofen and its salts

Rational Selection of Bio-Enabling Oral Drug Formulations – A PEARRL Commentary

Calculation of drug-polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating pharmaceutical formulations

Jennifer Dressman - 40 years of Oral Drug Absorption

The Landscape of Potential Small and Drug Substance Related Nitrosamines in Pharmaceuticals

Avoiding N-nitrosodimethylamine formation in metformin pharmaceuticals by limiting dimethylamine and nitrite

Industrial Pharmaceutics

Lipophilicity and hydrophobicity considerations in bio‐enabling oral formulations approaches – a PEARRL review

Comparison of Nephelometric, UV-Spectroscopic, and HPLC Methods for High-Throughput Determination of Aqueous Drug Solubility in Microtiter Plates

Incorporation of HPMCAS during loading of glibenclamide onto mesoporous silica improves dissolution and inhibits precipitation

Biowaiver Monograph for Immediate-Release Solid Oral Dosage Forms: Isavuconazonium Sulfate

NDMA analytics in metformin products: Comparison of methods and pitfalls

Absolute Configuration of Pharmaceutical Research Compounds Determined by X‐ray Powder Diffraction

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